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| 1 | A new breakthrough:ESD using a newly developed grasping type scissor forceps for early gastrointestinal tract neoplasms显示文摘Endoscopic submucosal dissection(ESD) has allowed the achievement of histologically curative en bloc resection of gastrointestinal neoplasms regardless of size,permitting the resection of previously non-resectable tumors.The ESD technique for treatment of early gastric cancer has spread rapidly in Japan and a few other Asian countries due to its excellent eradication rate compared to endoscopic mucosal resection.Although numerous electrosurgical knives have been developed for ESD,technical difficulties and high complication rates(bleeding and perforation) have limited their use worldwide.We developed the grasping type scissor forceps(GSF) to resolve such ESD-related problems.Our animal and preliminary clinical studies showed that ESD using GSF is a safe(no intraoperative complication) and technically efficient(curative en bloc resection rate 92%) method for dissection of early gastrointestinal tumors.The use of GSF is a promising option for performing ESD on early stage GI tract tumors both safely and effectively. | Kazuya Akahoshi Hidefumi Akahane | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，3： | 17 |
| 2 | Endoscopic submucosal dissection of a rectal carcinoid tumor using grasping type scissors forceps显示文摘Endoscopic submucosal dissection (ESD) with a knife is a technically demanding procedure associated with a high complication rate. The shortcomings of this method are the inability to fix the knife to the target lesion, and compression of the lesion. These can lead to major complications such as perforation and bleeding. To reduce the risk of complications related to ESD, we developed a new grasping type scissors forceps (GSF), which can grasp and incise the targeted tissue using electrosurgical current. Colonoscopy on a 55-year-old woman revealed a 10-mm rectal submucosal nodule. The histological diagnosis of the specimen obtained by biopsy was carcinoid tumor. Endoscopic ultrasonography demonstrated a hypoechoic solid tumor limited to the submucosa without lymph node involvement. It was safely and accurately resected without unexpected incision by ESD using a GSF. No delayed hemorrhage or perforation occurred. Histological examination confirmed the carcinoid tumor was completely excised with negative resection margin. | Kazuya Akahoshi Yasuaki Motomura Masaru Kubokawa Noriaki Matsui Manami Oda Risa Okamoto Shingo Endo Naomi Higuchi Yumi Kashiwabara Masafumi Oya Hidefumi Akahane Haruo Akiba | 2009 | World Journal of Gastroenterology2009，15，17： | 4 |
| 3 | An unusual enteropathy-associated T-cell lymphoma with MYC translocation arising in a Japanese patient:A case report显示文摘Enteropathy-associated T-cell lymphoma(EATL) is a rare peripheral T-cell lymphoma classified into 2 types,with or without celiac disease,based on histology.Type 2 EATL is less commonly associated with celiac disease,in which cells are characterized by being monomorphic and small-to medium-sized.Cells are characterized by CD8 and CD56 expression and c-MYC oncogene locus gain.We present an atypical case of type 2 EATL in the jejunum,with human T-lymphotropic virus-1 that was CD4-CD8+ CD56-CD30-CD25-TIA-1+ and granzyme B+ on immunohistological staining.It also displayed translocation of chromosome 8p24(c-MYC),as determined by fluorescent in situ hybridization.Mucosal spreading and intraepithelial invasion by lymphoma with villous atrophy were detected adjacent to the mucosal layer.The lymphoma may be derived from intraepithelial CD8+ T cells,similar to celiac disease. | Kenji Okumura Masahiko Ikebe Tatsuro Shimokama Morishige Takeshita Nao Kinjo Keishi Sugimachi Hidefumi Higashi | 2012 | World Journal of Gastroenterology2012，18，19： | 3 |
| 4 | Mass acquisition of human periodontal ligament stem cells显示文摘The periodontal ligament(PDL)is an essential fibrous tissue for tooth retention in the alveolar bone socket.PDL tissue further functions to cushion occlusal force,maintain alveolar bone height,allow orthodontic tooth movement,and connect tooth roots with bone.Severe periodontitis,deep caries,and trauma cause irreversible damage to this tissue,eventually leading to tooth loss through the destruction of tooth retention.Many patients suffer from these diseases worldwide,and its prevalence increases with age.To address this issue,regenerative medicine for damaged PDL tissue as well as the surrounding tissues has been extensively investigated regarding the potential and effectiveness of stem cells,scaffolds,and cytokines as well as their combined applications.In particular,PDL stem cells(PDLSCs)have been well studied.In this review,I discuss comprehensive studies on PDLSCs performed in vivo and contemporary reports focusing on the acquisition of large numbers of PDLSCs for therapeutic applications because of the very small number of PDLSCs available in vivo. | Hidefumi Maeda | 2020 | World Journal of Stem Cells2020，12，9： | 3 |
| 5 | Elevated Serum Periostin Levels in Patients with Bone Metastases from Breast but not Lung Cancer显示文摘 | Hidefumi Sasaki Chih-Yi Yu Meiru Dai Carmen Tam Massimo Loda Daniel Auclair Lan Bo Chen Anthony Elias | 2003 | Breast Cancer Research and Treatment2003，，3： | 2 |
| 6 | Percutaneous radiofrequency ablation of clinical stage I non–small cell lung cancer显示文摘 | Takao Hiraki Hideo Gobara Hidefumi Mimura Yusuke Matsui Shinichi Toyooka Susumu Kanazawa | 2011 | The Journal of Thoracic and Cardiovascular Surgery2011，，1： | 2 |
| 7 | Protection against infections by oral lactoferrin: Evaluation in animal models显示文摘 | Susumu Teraguchi Hiroyuki Wakabayashi Hidefumi Kuwata | 2004 | BioMetals2004，17，： | 1 |
| 8 | Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion显示文摘 | Kazuo Washida Masafumi Ihara Keiko Nishio Youshi Fujita Takakuni Maki Mahito Yamada Jun Takahashi Xiaofeng Wu Takeshi Kihara Hidefumi Ito Hidekazu Tomimoto Ryosuke Takahashi | 2010 | Stroke2010，，8： | 1 |
| 9 | Two-degree-of-freedom PID controllers显示文摘 | MITUHIKO Araki HIDEFUMI Taguchi | 2003 | International Journal of Control Automation and Systems2003，1，4： | 1 |
| 10 | An autonomous rice transplanter guided by global positioning system and inertial measurement unit显示文摘 | Nagasaka Yoshisada Saito Hidefumi Tamaki Katsuhiko | 2009 | Journal of Field Robotics2009，26，67： | 1 |
| 11 | Influence of emulsion and powder size on the stability of encapsulated dlimonene by spray drying显示文摘 | Apinan Soottitantawat Fanny Bigeard Hidefumi Yoshii | | 0，，01： | 1 |
| 12 | Prognosis of recurrent non?small cell lung cancer following completeresection显示文摘 | Hidefumi Sasaki Ayumi Suzuki Tsutomu Tatematsu Masayuki Shitara Yu Hikosaka Katsuhiro Okuda Satoru Moriyama Motoki Yano Yoshitaka Fujii | 2014 | Oncology Letters2014，，4： | 1 |
| 13 | Surgical treatment for urthral recurrence after ileal neobladder reeomstruetion in patients with bladder cancer 显示文摘 | Kenji Y Hiroyuki N Hidefumi K | 2006 | BJU international2006，98，： | 1 |
| 14 | AComparative Study of Urban Environment in East Asia: Stage Model of Urban EnvironmentalEvolution显示文摘 | Xuemei Bai Hidefumi Imurab | 2000 | International Review for Environmental Strategies2000，，1： | 1 |
| 15 | Endoscopic submucosal dissection by using a grasping-type scissors forceps: a preliminary clinical study (with video)显示文摘 | Kazuya Akahoshi Kuniomi Honda Hidefumi Akahane Haruo Akiba Noriaki Matsui Yasuaki Motomura Masaru Kubokawa Shingo Endo Naomi Higuchi Masafumi Oya | 2008 | Gastrointestinal Endoscopy2008，，7： | 1 |
| 16 | Noncovalent modification of the heine-pocket of apomyoglobin by a 1,10-phenanthroline derivative显示文摘 | HIDEFUMI M HIDEAKI Y | 2006 | Bioorganic & Medicinal Chemistry Letters2006，16，： | 1 |
| 17 | Quantifying the cool island intensity of urban parks using ASTER and IKONOS data显示文摘 | Xin Cao Akio Onishi Jin Chen Hidefumi Imura | 2010 | Landscape and Urban Planning2010，，4： | 1 |
| 18 | Powdery encapsulation of d-limonene by kneading with mixed powders of β-cyclodextrin and maltodextrin at low water content显示文摘 | Takeshi Furuta Hidefumi Yoshii Takashi Kobayashi | 1994 | Biosci Biotech Biochem1994，58，： | 1 |
| 19 | Production of fine powder from silk by radiation 显示文摘 | Hidefumi Takeshite | 2001 | Macromolecu lar Materials and Engineering2001，283，1： | 1 |
| 20 | Two-degree-of-freedom PID controllers显示文摘 | Mituhiko A Hidefumi T | 2003 | Int J of Control Automation and Systems2003，1，4： | 1 |
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