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    题名 作者 年代 出处 被引量
1Enhanced nutrients removal from municipal wastewater through biological phosphorus removal followed by partial nitritation/anammox显示文摘Yandong Yang Liang Zhang Hedong Shao Shujun Zhang PengchaoGu Yongzhen Peng 2017Frontiers of Environmental Science & Engineering2017,11,2:10
2Neuronal reprogramming in treating spinal cord injury显示文摘Spinal cord injury represents a devastating central nervous system injury that could impair the mobility and sensory function of afflicted patients.The hallmarks of spinal cord injury include neuroinflammation,axonal degeneration,neuronal loss,and reactive gliosis.Furthermore,the formation of a glial scar at the injury site elicits an inhibitory environment for potential neuroregeneration.Besides axonal regeneration,a significant challenge in treating spinal cord injury is to replenish the neurons lost during the pathological process.However,despite decades of research efforts,current strategies including stem cell transplantation have not resulted in a successful clinical therapy.Furthermore,stem cell transplantation faces serious hurdles such as immunorejection of the transplanted cells and ethical issues.In vivo neuronal reprogramming is a recently developed technology and leading a major breakthrough in regenerative medicine.This innovative technology converts endogenous glial cells into functional neurons for injury repair in the central nervous system.The feasibility of in vivo neuronal reprogramming has been demonstrated successfully in models of different neurological disorders including spinal cord injury by numerous laboratories.Several reprogramming factors,mainly the pro-neural transcription factors,have been utilized to reprogram endogenous glial cells into functional neurons with distinct phenotypes.So far,the literature on in vivo neuronal reprogramming in the model of spinal cord injury is still small.In this review,we summarize a limited number of such reports and discuss several questions that we think are important for applying in vivo neuronal reprogramming in the research field of spinal cord injury as well as other central nervous system disorders.Xuanyu Chen Hedong Li 2022Neural Regeneration Research2022,17,7:6
3Applications of online monitoring technology for tailings dam on digital mine显示文摘Considering its structural features, geometric shapes, service mode, environmental media, mechanical behavior, etc, the special nature and complexity of tailings dam were summarized. The technical approach to safety management for tailings dam was proposed, which is the on-line automated monitoring and early warning information. The results show that a strong theoretical basis can be provided for security monitoring and security management of tailings dam. Online automated monitoring system for tailings dam has full implementation of the information. It is applied widely in Lingnan gold mine, Xiadian gold mine and Hedong gold mine in Zhaoyuan, Shandong Province, and achieves good effect.YU Guang-ming1, SONG Chuan-wang1, ZOU Jing-bo1, WU Yan-xia1, PAN Yong-zhan1, LI Liang1, LI Ran1, WANG Pei-shou2, WANG Yan-lei2 1. School of Civil Engineering, Qingdao Technological University, Qingdao 266033, China 2. Hedong Goldmine, Zhaojin Mining Industry Company, Zhaoyuan 265400, China 2011中国有色金属学会会刊:英文版2011,21,S3:5
4Improved Mechanical Properties of Textile Reinforced Concrete Thin Plate显示文摘Textile reinforced concrete (TRC) is especially suitable for the thin-walled and light-weight structural elements with a high load-bearing capacity. For this thin element, the concrete cover thickness is an important factor in affecting the mechanical and anti-crack performance. Therefore, the influences of the surface treatment of the textile and mixing polypropylene fiber into the concrete on the properties of the components with different cover thickness were experimentally studied with four-point bending tests. The experimental results show that for the components with the same cover thickness, sticking sand on epoxy resin-impregnated textile and adding short fiber into the concrete are helpful to improve their mechanical performance. The 2-3 mm cover thickness is enough to meet the anchorage requirements of the reinforcement fiber and the component has good crack pattern and mechanical behavior at this condition. Comparison between the calculated and the experimental values of flexural capacity reveals satisfactory agreement. Finally, based on the calculation model of the crack spacing of reinforced concrete structures, the crack extension of this thin-wall component was qualitatively analyzed and the same results with the experimental were obtained.尹世平 徐世烺 LI Hedong 2013Journal of Wuhan University of Technology(Materials Science)2013,28,1:4
5MicroRNAs as potential therapeutics for treating spinal cord injury显示文摘MicroRNAs are a class of recently discovered,small non-coding RNAs that have been shown to play essential roles in a vast majority of biological processes.Very little is known about the role of microRNAs during spinal cord injury.This review summarizes the changes in expression levels of microRNAs after spinal cord injury.These aberrant changes suggest that microRNAs play an important role in inflammation,oxidative stress,apoptosis,glial scar formation and axonal regeneration.Given their small size and specificity of action,microRNAs could be potential therapeutics for treating spinal cord injury in the future.There are rapidly developing techniques for manipulating microRNA levels in animals;we review different chemical modification and delivery strategies.These may provide platforms for designing efficient microRNA delivery protocols for use in the clinic.Hualin Yan Peiwei Hong Mei Jiang Hedong Li 2012Neural Regeneration Research2012,7,17:3
6Electrical Conductivity,Oil Absorption and Electric Heating of Carbon Black-modified Carbon Nanofibers显示文摘Carbon-black-modified carbon nanofibers were prepared by electrospinning,and the effects of the carbon black content and processing temperature on the physical and chemical properties of the resulting composites were investigated.The results showed that the conductivity of carbon-black-modified nanofibers increased with the carbon black content.The addition of carbon black in a 20%mass ratio increased the conductivity of the composite(0.75 S/cm)by 230%compared with the undoped nano-fiber(2.47 S/cm),while the adulteration with 5%CB allowed the preservation of the mechanical properties of the composites.The fabricated carbon-black/carbon-nanocomposite fibers exhibited excellent oil absorption and electrothermal conversion performance.Furthermore,the conductivity and oil absorption capacity increased with increasing carbonization temperature.With a carbonization temperature of 1000℃(5%carbon black),the voltage was 31 V,the current was 0.66 A,and the surface temperature of the composite reached 234.1℃.The overall enhancement in physical properties upon the addition of even low amounts of carbon black makes these composites advantageous for future industrial applications.HUANG Hedong GUO Zeyu YANG Pengyan CHEN Peng Wu Jie 2021Chemical Research in Chinese Universities2021,37,3:2
7Tensile and flexural properties of ultra high toughness cemontious composite显示文摘Hedong Li Shilang Xu Christopher K. Y. Leung 2009Journal of Wuhan University of Technology - Mater Sci Ed2009,,4:2
8Preparation of soluble p-aminobenzoyl chitosan ester by Schiff's base and antibacterial activity of the derivatives显示文摘Wang Jiangtao Wang Hedong 2011International Journal of Biological Macromolecules2011,48,3:1
9An un- structured grid, finite-volume, three-dimensional, primitive equations ocean model: Application to coastalocean and estuaries显示文摘Chen Changsheng Liu Hedong Robert C B 2003Journal of Atmospheric and Oceanic Technology2003,20,:1
10Stress transfer and fracture propagation in different kinds of adhesive joints显示文摘Zhishen Wu Hong Yuan Hedong Niu 2002Journal of Engineering Mechanics2002,128,5:1
11An Unstructured Grid,Finite-Volume,Three-Dimensional,Primitive Equations Ocean Model:Application to Coastal Ocean and Estuaries显示文摘CHANGSHENG CHEN HEDONG LIU ROBERT C 2003J of Atmospheric and Oceanic Technology2003,20,:1
12Tensile and flexural properties of ultra high toughness cemontious composite显示文摘Hedong Li Shilang Xu Christopher K. Y. Leung 2009Journal of Wuhan University of Technology - Mater Sci Ed2009,,4:1
13Improved mechanical properties of textile reinforced concrete thin plate显示文摘Shiping Yin Shilang Xu Hedong Li 2013Journal of Wuhan University of Technology-Mater Sci Ed2013,,1:1
14Numerical analysis of debonding mecha- nisms in FRP-strengthen RC beams显示文摘NIU Hedong WU Zhishen 2005Computer-Aided Civil and Infrastructure Engineering2005,,20:1
15Simultaneous determination of Repaglinide and Irbesartan in biological plasmas using micellar enhanced excitation-emission matrix fluorescence coupled with ATLD method显示文摘A highly sensitive and selective 3D excitation-emission fluorescence method has been proposed to rapidly quantify the combined antidiabetics Repaglinide(Re) and Irbesartan(Ir) in rat and human plasmas with the aid of second-order calibration method based on alternating trilinear decomposition(ATLD) method. Re and Ir with weak fluorescence can be endowed with strong fluorescent property by changing the microenvironment in samples and improving the fluorescence quantum yield by using an appropriate micellar enhanced surfactant. The enhanced excitation-emission matrix fluorescence of Re and Ir can be accurately resolved and can simultaneously attain the optimal concentration even in the presence of a potentially strong intrinsic fluorescence from complex biological matrices, such as rat and human plasmas, by using the ATLD method, which completely exploits the 'second-order advantage'. The average recoveries of Re and Ir obtained from ATLD with the factor number of 3(N=3) were 101.0%±4.3% and 99.1%±4.1% for rat plasma and 100.5%±5.4% and 97.1%±3.6% for human plasma. Several statistical methods, including Student's t-test, figures of merit, and elliptical joint confidence region, have been utilized to evaluate the accuracy of the proposed method. Results show that the developed method can maintain second-order advantage in simultaneous determinations of the weak fluorescent analytes of interest in different biological plasma matrices.Haiyan Fu Hedong Li Mei Shao Tianming Yang Xu Zhang Rujing Xu Yujuan Wei Shuhua Chen Chuang Ni Hailong Wu 2016Science China Chemistry2016,59,7:1
16Stress transfer and frac- ture propagation in different kinds of adhesive joints显示文摘WU Zhishen YUAN Hong NIU Hedong 2002Journal of Engineering Mechanics2002,128,:1
17Study on the structural changes of bovine serum albumin with effects on polydatin binding by a multitechnique approach显示文摘Xialian Peng Di Yao Yingming Pan Qing Yu Shouhai Ni Hedong Bian Fuping Huang Hong Liang 2011Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2011,,1:1
18Potential use of strain hardening ECC in permanent formwork with small scale flexural beams显示文摘Hedong Li Christopher K. Y. Leung Shilang Xu Qian Cao 2009Journal of Wuhan University of Technology - Mater Sci Ed2009,,3:1
19Oral nano-antioxidants improve sleep by restoring intestinal barrier integrity and preventing systemic inflammation显示文摘Sleep deprivation(SD)is a severe public health threat that can cause systemic inflammation and nerve damage.Few effective and side-effect-free drugs are available to address SD.However,the bidirectional communications between the brain and gut provide new strategies for anti-SD therapeutics.Here we explored oral delivery of fullerene nano-antioxidants(FNAO)in the SD model to improve sleep by regulating abnormal intestinal barrier and systemic inflammation via the brain-gut axis.SD caused excessive reactive oxygen species(ROS)production and hyperactive inflammatory responses in the intestines of zebrafish and mouse models,leading to disturbed sleep patterns and reduced brain nerve activity.Of note,based on the property of the conjugatedπbond of the C_(60)structure to absorb unpaired electrons,oral FNAO efficiently reduced the excessive ROS in the intestines,maintained redox homeostasis and intestinal barrier integrity,and ameliorated intestinal and systemic inflammation,resulting in superior sleep improvement.Our findings suggest that maintaining intestinal homeostasis may be a promising avenue for SD-related nerve injury therapy.Zhanfeng Wu Lei Liu Lei Li Xinran Cao Wang Jia Xiaodan Liao Zhongpu Zhao Hedong Qi Guoqiang Fan Huiqiang Lu Chunying Shu Mingming Zhen Chunru Wang Chunli Bai 2023National Science Review2023,10,12:1
20CPL+:an improved approach for evaluating the local completeness of event logs显示文摘Yang Hedong Wen Lijie Wang Jianmin 2014Information Processing Letters2014,114,11:1
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