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| 1 | Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease. | Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff | 2015 | World Journal of Gastrointestinal Oncology2015，7，9： | 6 |
| 2 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 3 | Processing-structure-property relationships in Poly (ethylene terephthalate) blown film 显示文摘 | Ma T C Han C D | 1988 | J App Polym Sci1988，35，： | 1 |
| 4 | Sol - gel process doped ZnO nanopowders and their grown growth显示文摘 | KANG X Y WANG T D HAN Y | 1997 | Mater Res Bull1997，32，9： | 1 |
| 5 | Fast speciation of mercury in seawater by short-column high-performance liquid chromatography hyphenated to inductively coupled plasma spectrometry after on-line cation exchange column preconcentration 显示文摘 | Jia X Y Gong D R Han Y Wei C Duan T C Chen H T | 2012 | Talanta2012，88，： | 1 |
| 6 | hiCUDA:High-level GPGPU programming显示文摘 | Han T D Abdelrahman T S | 2011 | IEEE Transactions on Parallel and Distributed Systems2011，22，1： | 1 |
| 7 | Microcystin (-LR) affects hormones level of male mice by dama- ging hypothalamic-pituitary system 显示文摘 | WANG X T YING F CHEN Y HAN X D | 2012 | Toxicon2012，59，2： | 1 |
| 8 | Effect of glutamine on apoptosis of intestinal epithelial cells of severe acute pancreatitis rats receiv- ing nutritional support in different ways显示文摘 | HAN T LI X CAI D | 2013 | Int J Clin Exp Pathol2013，6，3： | 1 |
| 9 | Application of carbon nanotubes to field emission displays显示文摘 | Chung D S Han I T | 2001 | Diamond and Related Materials2001，10，： | 1 |
| 10 | Effects of vanadium addition on nucleation and growth of pearlite in high carbon steel 显示文摘 | Han K Mottishaw T D Smith G D W | 1994 | Mater Sci Technol1994，10，11： | 1 |
| 11 | Postthrombotic syndrome complicating a case of May-Thurner syndrome despite endovascular therapy:case report and review显示文摘 | Ludwig B Han T Amundson D | 2006 | Chest2006，129，5： | 1 |
| 12 | Effect of gas bubbling and impeller agitation on degassing kinetics during magnesium alloy (AZ91D) melt recycling-Water model approach显示文摘 | HAN J W KIM D J YOU B D ENGH T A | 2003 | Materials Science Forum2003，439，： | 1 |
| 13 | Discrete element simulation of the dynamics of high energy planetary ball milling processes显示文摘 | FENG Y T HAN K OWEN D R J | 2004 | Materials Science and Engineering:A2004，，： | 1 |
| 14 | Sphere packing with a geometricbased compression algorithm 显示文摘 | Han K Feng Y T Owen D R | 2005 | Powder Technology (S0032-5910)2005，155，1： | 1 |
| 15 | 查看详情显示文摘 | Yan L W Duan X R Ding X T Dong J Q Yang Q W Liu Y Zou X L Liu D Q Xuan W M Chen L Y Rao J Song X M Huang Y Mao W C Wang Q M Li Q Cao Z Li B Cao J Y Lei G J Zhang J H Li X D Chen W Cheng J Cui C H Cui Z Y Deng Z C Dong Y B Feng B B Gao Q D Han X Y Hong W Y | | 0，，： | 1 |
| 16 | Contrast-enhanced ultrasound for dif- ferentiation of benign and malignant thyroid lesions: meta- analysis显示文摘 | Yu D Han Y Chen T | 2014 | Otolaryngol Head Neck Surg2014，151，6： | 1 |
| 17 | Fabrication ofSuperhydrophobic Surface from a Supramolecular Or-ganosilane with Quadruple Hydrogen Bonding显示文摘 | HAN J T LEE D H RYU C Y | 2004 | Journal of the American Chemical Society2004，126，： | 1 |
| 18 | Fabrication of superhydrophobic surface from a supramolecular organosilane with quadruple hydrogen bonding显示文摘 | Han J T Lee D H Ryu C Y Cho K | 2004 | J Am Chem Soc2004，126，15： | 1 |
| 19 | A modified septoplasty with three high tension lines resection 显示文摘 | Wang T Han D Zhang L | 2010 | Acta Otolaryngol2010，130，3： | 1 |
| 20 | Astaxanthin in Microalgae: Pathways, Functions and Biotechnological Implications 显示文摘 | Han D X Li Y T Hu Q | 2013 | Algae2013，28，2： | 1 |
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