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| 1 | Heyan Kuntai capsule versus dehydroepiandrosterone in treating Chinese patients with infertility caused by diminished ovarian reserve: a multicenter, randomized controlled trial显示文摘OBJECTIVE: To evaluate the clinical efficacy and safety of Heyan Kuntai capsule(HYKT) in treating women with infertility caused by diminished ovarian reserve(DOR).METHODS: One hundred eight eligible patientsfrom three Chinese hospitals were randomly divided into an HYKT treatment group(n = 55) or a dehydroepiandrosterone(DHEA) treatment group(n =53). Patients in the HYKT group were treated orally with four 0.5 g HYKT three times a day; patients in the DHEA group were treated with one 25.0 mg DHEA capsule three times a day. All patients were treated for 3 months and followed up over a3-month period.RESULTS: Of 108 patients, 12 dropped out: six from the HYKT group, and six from the DHEA group. Eleven patients got pregnant during the treatment. Serum anti-Müllerian hormone levels and antral follicle counts increased significantly in both groups after treatment(P < 0.05) especially in the HYKT group(P < 0.05). Serum follicle stimulating hormone(FSH) levels and FSH/luteinizing hormone ratios decreased(P < 0.05) with no significant difference between the two groups. Estradiol levels in the HYKT group and DHEA-sulfate levels in the DHEA group both increased(P < 0.05). The spontaneous pregnancy rates were 12% and 11% in the HYKT and DHEA groups, respectively(not significant). During the follow-up period, 16 patients in the HYKT group underwent in vitro fertilization-embryo transfer(IVF-ET) and the number of retrieved oocytes was(5.1 ± 1.8). In DHEA group, 20 patients underwent IVF-ET and the number of retrieved oocyte was(4.2 ± 1.9)(not significant); clinical pregnancy rates were 38% in the HYKT group and 20%in DHEA group(not significant). No significant adverse reactions were observed.CONCLUSION: HYKT can improve the ovarian re-serve and hormone levels in patients with infertility caused by DOR. Pregnancy rates after HYKT treatment were similar to those of DHEA treatment.HYKT might be an alternative to the treatment of infertility caused by DOR. | Gao Hui Xia Tian Ma Ruihong Zhao Zhimei Song Xueru Wang Baojuan Liu Lijing Han Kaimei Wang Guoqing Fu Yu Hao Guimin | 2017 | Journal of Traditional Chinese Medicine2017，37，4： | 14 |
| 2 | Microcrack analysis of Sanya grantite fragments from rockburst tests显示文摘Fractures running along a plane reflect the cracking progress.In this paper uniaxial and rockburst tests on a group of granite specimens from Sanya province are described.Scanning electron microscopic imaging was used to characterize the fragments.Fractal fracture mechanics were used to analyze the microcracks in terms of both the crack type and the mineral constituent.A statistical analysis showed that the area of inter-granular cracking exceeds that of intra-granular cracking.Several types of crack were observed in the cracked areas.The percentage of intra-granular cracks in fragments from rockburst tests exceeds that from uniaxial compression tests.The results also showed that feldspar deformation was the main cause of fracture and that the consolidation along quartz grain boundaries was another weak area in the granite.Cracking along quartz grains had enough energy to enter the quartz crystal in the rockburst samples.All these results contribute to further research on rockburst mechanics. | HE, Manchao NIE, Wen HAN, Liqiang LING, Lijing | 2010 | Mining Science and Technology2010，20，2： | 11 |
| 3 | Comparative genomic and transcriptomic analyses uncover the molecular basis of high nitrogen-use efficiency in the wheat cultivar Kenong 9204显示文摘Studying the regulatory mechanisms that drive nitrogen-use efficiency(NUE)in crops is important for sustainable agriculture and environmental protection.In this study,we generated a high-quality genome assembly for the high-NUE wheat cultivar Kenong 9204 and systematically analyzed genes related to nitrogen uptake and metabolism.By comparative analyses,we found that the high-affinity nitrate transporter gene family had expanded in Triticeae.Further studies showed that subsequent functional differentiation endowed the expanded family members with saline inducibility,providing a genetic basis for improving the adaptability of wheat to nitrogen deficiency in various habitats.To explore the genetic and molecular mechanisms of high NUE,we compared genomic and transcriptomic data from the high-NUE cultivar Kenong 9204(KN9204)and the low-NUE cultivar Jing 411 and quantified their nitrogen accumulation under high-and low-nitrogen conditions.Compared with Jing 411,KN9204 absorbed significantly more nitrogen at the reproductive stage after shooting and accumulated it in the shoots and seeds.Transcriptome data analysis revealed that nitrogen deficiency clearly suppressed the expression of genes related to cell division in the young spike of Jing 411,whereas this suppression of gene expression was much lower in KN9204.In addition,KN9204 maintained relatively high expression of NPF genes for a longer time than Jing 411 during seed maturity.Physiological and transcriptome data revealed that KN9204 was more tolerant of nitrogen deficiency than Jing 411,especially at the reproductive stage.The high NUE of KN9204 is an integrated effect controlled at different levels.Taken together,our data provide new insights into the molecular mechanisms of NUE and important gene resources for improving wheat cultivars with a higher NUE trait. | Xiaoli Shi Fa Cui Xinyin Han Yilin He Long Zhao Na Zhang Hao Zhang Haidong Zhu Zhexin Liu Bin Ma Shusong Zheng Wei Zhang Jiajia Liu Xiaoli Fan Yaoqi Si Shuiquan Tian Jianqing Niu Huilan Wu Xuemei Liu Zhuo Chen Deyuan Meng Xiaoyan Wang Liqiang Song Lijing Sun Jie Han Hui Zhao Jun Ji Zhiguo Wang Xiaoyu He Ruilin Li Xuebin Chi Chengzhi Liang Beifang Niu Jun Xiao Junming Li Hong-Qing Ling | 2022 | Molecular Plant2022，15，9： | 6 |
| 4 | Genesis and Implications of the Composition and Sedimentary Structure of Fine-Grained Carbonate Rocks in the Shulu Sag显示文摘Fine-grained carbonate rocks, which extensively occur in the Eocene strata in the Shulu sag, Bohai Bay Basin, North China, represent an unconventional, fine-grained carbonate reservoir. However, previous studies have ignored the complexity of the lithofacies components and their formation mechanisms. Fine-grained carbonate rocks are typical reservoirs in which hydrocarbons form and gather. A better understanding of the nature of these rocks is extremely important for evaluating the quality of unconventional, fine-grained carbonate reservoirs. Various lithofacies components were discriminated in this study with a combination of petrographic observations and carbon isotope analyses. These finegrained carbonate rocks comprise terrigenous, biogenic and diagenetic materials. Terrigenous input and biologically induced precipitation are the main sources of the materials in the lake. Five lithofacies were identified based on the observations of sedimentary features(core and thin section) and mineralogical data:(1) varve-like laminated calcilutite,(2) graded laminated calcilutite,(3) interlaminated calcisiltitecalcilutite,(4) massive calcilutite, and(5) massive calcisiltite-calcarenite. Their origins were recorded by various lithofacies components, which are controlled by the interactions of physical, chemical and biological processes. This study indicated that the lithology of the bedrocks was the key factor controlling carbonate accumulation. The tectonics and climate can influence the weathering and types of lithofacies. Primary productivity controlled the precipitation of the endogenic calcite. These factors jointly determined the abundant fine-grained carbonate rocks that have accumulated in the Shulu sag. | Xiangxin Kong Zaixing Jiang Chao Han Lijing Zheng Yiming Zhang Ruifeng Zhang Jianzhang Tian | 2017 | Journal of Earth Science2017，28，6： | 6 |
| 5 | Vocal cord mucosal flap for the treatment of acquired anterior laryngeal web显示文摘 | Xiao Yang Wang Jun Han Demin Ma Lijing Ye Jingying Xu Wen | 2014 | Chinese Medical Journal2014，，7： | 6 |
| 6 | Characterization and Fine Mapping of a Necrotic Leaf Mutant in Maize(Zea mays L.)显示文摘玉米(Zea mays L.) 是商业地重要的庄稼。它的收益能被变化在引起死亡的 biosynthetic 和 degradative 小径减少。在这份报纸,我们描述坏死的叶(nec-t ) 异种,从一根生来的线被获得, 81647。nec-t 异种植物与坏死的点有黄叶子,减少了叶绿素内容,并且变白的幼苗在正常生长条件下面死了。传播电子显微镜学揭示了散布 thylakoids,并且每房间减少了 grana lamellae 和叶绿体的数字。组织化学的染色建议 nec-t 叶子的那点形成可能由于房间死亡。基因分析证明那坏死被一个后退的地点的变化引起。用简单顺序重复标记, Nec-t 基因在染色体 2 的短手臂上在 mmc0111 和 bnlg2277 之间被印射。有从一张 F2 人口的变异的显型的 1287 个个人的一个总数被用于物理印射。Nec-t 基因在标记 T31 和 H8 之间位于 131.7 kb 的一个物理区域以内。 | Lijing Wang Shuai Han Shiyi Zhong Haizhong Wei Yanjun Zhang Yan Zhao Baoshen Liu | 2013 | Journal of Genetics and Genomics2013，40，6： | 5 |
| 7 | New Bulb Turbine with Counter-rotating Tandem-runner显示文摘With the increasing demand for the clean sustainable power, the turbine design urgently turns to increase the capability significantly toward higher head for generating larger power. Currently, there are many studies in the field of the bulb turbine with single-stage runner, though reports about counter-rotating tandem-runner are rare. However, the further high-head application with the single-stage runner is very difficult to achieve due to the limit of the specific speed. In this paper, a new bulb turbine with the tandem-runner is designed in order to substantially increase the applicable limit toward higher head with larger power. A half of the net head is absorbed by the frontal runner which can generate output power, while the remaining half is absorbed by the rear runner. To generate the Euler energy required for the rear runner, the frontal runner has the counter-rotation against the rear runner so that the counter-rotating tandem-runner can meet the purpose of double head and power under the same size as the conventional bulb turbine. Supply and demand of Euler energy between the two runners are thoroughly optimized through the detailed flow analysis, in order to secure the stable operation. As a result, the interference of Euler energies between the outflow from the frontal runner and the inflow to the rear runner is confirmed to be very small on the counter-rotating interface between the two runners. The prediction method of on-cam performance between the two adjustable runners is also developed numerically, which provides optimal flow between the two runners. This research provides a theoretical basis for the optimal design and operation of the counter-rotating tandem-runner bulb turbines. | HAN Fengqin YANG Lijing YAN Shijie KUBOAT Takashi | 2012 | Chinese Journal of Mechanical Engineering2012，25，5： | 4 |
| 8 | Study and Commercial Application of Graded Optimization of Catalysts for Fixed Bed Residue Upgrading Unit显示文摘反的催化剂装载的 SHIFT-G 技术被用来优化在对待联合起来的残余水疗院分级的催化剂。结果,从飞行员测试和商业单位拿,证明了相当分级系统罐头的优化催化剂散布反应负担,有效地改进水疗院的性质对待的产品,延长操作周期并且支持经济好处。 | Han Zhaoming Jiang Lijing | 2007 | China Petroleum Processing & Petrochemical Technology2007，9，2： | 2 |
| 9 | Nonisothermal crystallization behavior and mechanical properties of poly (butylene succinate)/silica nanocomposites 显示文摘 | Junjia Bian Lijing Han Xuemei Wang | 2010 | Journal of Applied Polymer Science2010，116，： | 1 |
| 10 | Nonisothermal crystallization behavior and mechanical properties of poly (butylene succinate)/silica nanocomposites 显示文摘 | Junjia Bian Lijing Han Xuemei Wang | 2010 | Journal of Applied Polymer Science2010，116，： | 1 |
| 11 | Thermal, Mechanical, and Rheological Properties of Poly(Propylene Carbonate) Cross-Linked with Polyaryl Polymethylene Isocyanate显示文摘 | Hao Yanping Ge Huanhuan Han Lijing | 2013 | Polymer Bulletin2013，70，7： | 1 |
| 12 | Thermal degradation behavior and gas phase flame‐retardant mechanism of polylactide/PCPP blends显示文摘 | Haijuan Lin Lijing Han Lisong Dong | 2014 | J Appl Polym Sci2014，，13： | 1 |
| 13 | Nonisothermal Crystallization Behavior and Mechanical Properties of Poly ( butylene succinate )/Silica Nanocomposites 显示文摘 | Bian Junjia Han Lijing Wang Xuemei | 2010 | Journal of Applied Polymer Science2010，116，： | 1 |
| 14 | Relation of tea ingestion to salivary redox and flow rate in healthy subjects显示文摘The biochemistry of human saliva can be altered by food intake.The benefits of tea drinking were extensively studied but the influence of tea ingestion on human saliva has not been revealed.The work aimed to investigate the immediate and delayed effect of vine tea,oolong tea and black tea intake on certain salivary biochemistry and flow rate.The saliva samples of healthy subjects were collected before,after and 30 min after tea ingestion.The chemical compositions and antioxidant capacity of tea samples were analyzed to correlate with salivary parameters.Principal component analysis indicated that the effects of vine tea consumption were dominated by increasing salivary flow rate(SFR),production rate of total protein(TPC),thiol(SH),malondialdehyde,catalase activity and antioxidant capacity(FRAP)in saliva.The antioxidant profile of studied tea samples(FRAP,polyphenols,flavonoids)was positively correlated with salivary SFR,TPC,SH and FRAP but negatively correlated with salivary uric acid concentration in saliva. | Pik Han Chong Qiaojuan He Suyun Zhang Jianwu Zhou Pingfan Rao Min Zhang Lijing Ke | 2023 | Food Science and Human Wellness2023，12，6： | 0 |
| 15 | Ecological impacts of the expansion of offshore wind farms on trophic level species of marine food chain显示文摘The global demand for renewable energy has resulted in a rapid expansion of offshore wind farms(OWFs)and increased attention to the ecological impacts of OWFs on the marine ecosystem.Previous reviews mainly focused on the OWFs’impacts on individual species like birds,bats,or mammals.This review collected numerous field-measured data and simulated results to summarize the ecological impacts on phytoplankton,zooplankton,zoobenthos,fishes,and mammals from each trophic level and also analyze their interactions in the marine food chain.Phytoplankton and zooplankton are positively or adversely affected by the‘wave effect’,‘shading effect’,oxygen depletion and predation pressure,leading to a ±10% fluctuation of primary production.Although zoobenthos are threatened transiently by habitat destruction with a reduction of around 60% in biomass in the construction stage,their abundance exhibited an over 90% increase,dominated by sessile species,due to the‘reef effect’in the operation stage.Marine fishes and mammals are to endure the interferences of noise and electromagnetic,but they are also aggregated around OWFs by the‘reef effect’and‘reserve effect’.Furthermore,the complexity of marine ecosystem would increase with a promotion of the total system biomass by 40% through trophic cascade effects strengthen and resource partitioning alternation triggered by the proliferation of filter-feeders.The suitable site selection,long-term monitoring,and life-cycle-assessment of ecological impacts of OWFs that are lacking in current literature have been described in this review,as well as the carbon emission and deposition. | Lijing Wang Bangguo Wang Wenxi Cen Rui Xu Yuwei Huang Xin Zhang Yinghui Han Yuanxun Zhang | 2024 | Journal of Environmental Sciences2024，，5： | 0 |
| 16 | Exploration of playa surface crusts in Qehan Lake, China through field investigation and wind tunnel experiments显示文摘Globally,many lakes are drying up,leaving exposed lakebeds where wind erosion releases dust and sand rich in salt and harmful heavy metals into the atmosphere.Therefore,understanding the characteristics and spatial distribution of playa surface crusts is important to recognize the manifestation of salt dust storms.The objective of this study was to explore the playa surface crust types as well as their spatial distribution and evolution of Qehan Lake in Inner Mongolia Autonomous Region,China to understand the salt dust release potential of different types of playa surface crusts.Various crust characteristics were investigated by field sampling in Qehan Lake,and playa surface crusts were further divided into five types:vegetated areas,salt crusts,clay flats,curly crusts,and margins.It should be noted that curly crusts were distributed in clay flats and covered only a small area in Qehan Lake.The spatial distribution characteristics of playa surface crust types were obtained by supervised classification of remote sensing images,and the salt dust release potential of crusts was explored by the wind tunnel experiments.The field investigation of Qehan Lake revealed that playa surface crust types had a circum-lake band distribution from the inside to the outside of this lake,which were successively vegetated areas,clay flats,salt crusts,and margins.The spatial distribution patterns of playa surface crust types were mainly controlled by the hydrodynamics of the playa,soil texture,and groundwater.There was a significant negative correlation between crust thickness and electrical conductivity.The results of the wind tunnel experiments showed that the initial threshold of friction wind velocity for the salt dust release was higher in clay flats(0.7–0.8 m/s)than in salt crusts(0.5–0.6 m/s).Moreover,the particle leap impact processes occurring under natural conditions may reduce this threshold value.Salinity was the main factor controlling the difference in the initial threshold of friction wind velocity for the salt dust release of clay flats and salt crusts.This study provides a scientific reference for understanding how salt dust is released from a lakebed,which may be used for ecological restoration of dry salt lakes. | LIU Dongwei HAN Lijing KOU Zihan GAO Xinyu WANG Jingjing | 2023 | Journal of Arid Land2023，15，5： | 0 |
| 17 | The Precursor of GRB211211A:A Tide-induced Giant Quake?显示文摘The equilibrium configuration of a solid strange star in the final inspiral phase with another compact object is generally discussed,and the starquake-related issue is revisited,for a special purpose to understand the precursor emission of binary compact star merger events(e.g.,that of GRB211211A).As the binary system inspirals inward due to gravitational wave radiation,the ellipticity of the solid strangeon star increases due to the growing tidal field of its compact companion.Elastic energy is hence accumulated during the inspiral stage which might trigger a starquake before the merger when the energy exceeds a critical value.The energy released during such starquakes is calculated and compared to the precursor observation of GRB211211 A.The result shows that the energy might be insufficient for binary strangeon-star case unless the entire solid strangeon star shatters,and hence favors a black hole-strangeon star scenario for GRB211211A.The timescale of the precursor as well as the frequency of the observed quasi-periodic-oscillation have also been discussed in the starquake model. | Enping Zhou Yong Gao Yurui Zhou Xiaoyu Lai Lijing Shao Weiyang Wang Shaolin Xiong Renxin Xu Shuxu Yi Garvin Yim Han Yue Zhen Zhang | 2024 | Research in Astronomy and Astrophysics2024，24，2： | 0 |
| 18 | Configuring topologically optimum vapor recompressed dividing-wall distillation columns to maximize operating efficiency显示文摘For dividing-wall distillation columns(DWDCs) separating a heavy-component dominated and wide boiling-point ternary(HCDWBT) mixture, a significant amount of excessive heat exists inevitably in stripping the heavy-component from the intermediate-component and it can be employed to initiate the development of vapor recompression heat pump(VRHP) assisted DWDC(VRHP-DWDC). Despite dividing wall may locate in the top, middle, and bottom, the optimum VRHP-DWDC is found to involve uniformlytwo VRHP circles. While the first one serves to compress and transform the excessive heat resulted from the separation of the heavy-component from the intermediate-component, the second one to compress and transform the overhead vapor stream of the light-component pre-heated sequentially with the condensate from the first one and the bottom product stream of the heavy-component, both releasing the temperature-elevated latent heat to the pre-fractionator's or common stripping section. The processing of two HCDWBT mixtures of benzene/toluene/o-xylene and n-pentane/n-hexane/n-heptane are selected to assess the derived optimum topological configurations of the VRHP-DWDC and their optimality is confirmed through detailed comparisons with the DWDC and two VRHP-DWDCs involving only one VRHP circle. The proposed strategy helps to tap the full potential of the VRHP-DWDC with considerably alleviated complication in process development. | Kejin Huang Shuaishuai Han Lijing Zang Haisheng Chen Yihang Luo Liang Zhang Yang Yuan Xing Qian Shaofeng Wang | 2023 | Chinese Journal of Chemical Engineering2023，57，5： | 0 |
| 19 | Effect of N-doping-derived solvent adsorption on electrochemical double layer structure and performance of porous carbon显示文摘N-doped porous carbon has been extensively investigated for broad electrochemical applications.The performance is significantly impacted by the electrochemical double layer(EDL),which is material dependent and hard to characterize.Limited understanding of doping-derived EDL structure hinders insight into the structure-performance relations and the rational design of high-performance materials.Thus,we analyzed the mass and chemical composition variation of EDL within electrochemical operation by electrochemical quartz crystal microbalance,in-situ X-ray photoelectron spectroscopy,and time-offlight secondary ion mass spectrometry.We found that N-doping triggers specifically adsorbed propylene carbonate solvent in the inner Helmholtz plane(IHP),which prevents ion rearrangement and enhances the migration of cations.However,this specific adsorption accelerated solvent decomposition,rendering rapid performance degradation in practical devices.This work reveals that the surface chemistry of electrodes can cause specific adsorption of solvents and change the EDL structure,which complements the classical EDL theory and provide guidance for practical applications. | Zhe-Fan Wang Cheng Tang Qian Sun Ya-Lu Han Zhi-Jian Wang Lijing Xie Shou-Chun Zhang Fang-Yuan Su Cheng-Meng Chen | 2023 | Journal of Energy Chemistry2023，，5： | 0 |
| 20 | miR-378 and its host gene Ppargc1β exhibit independent expression in mouse skeletal muscle显示文摘MicroRNAs (miRNAs) are implicated in multiple biological processes in physiological and pathological settings. Nearly half of the known miRNAs are classified as ‘intronic’ miRNAs because they are embedded within the introns of protein-coding or noncoding genes. Such miRNAs were thought to be processed from primary host gene transcripts and share the promoter of their host. Recent analyses predicted that some intronic miRNAs might be transcribed and regulated as independent units, but there is little direct evidence for this in a specific biological context. Here, we focused on miR-378, which is located within the first intron of the peroxisome proliferator-activated receptor γ coactivator 1-beta (Ppargc1β) gene and critically regulates skeletal muscle cell differentiation and muscle regeneration. We demonstrate that miR-378 and Ppargc1β exhibit distinct expression patterns during skeletal muscle cell differentiation. In terminally differentiated adult skeletal muscle tissues of mice, miR-378 is predominantly expressed in glycolytic muscle, whereas Ppargc1β is mainly expressed in oxidative soleus muscle. Mechanistically, miR-378, but not Ppargc1β, is regulated by the transcription factor, MyoD, in muscle cells. Our findings identify a regulatory model of miR-378 expression, thereby helping us to understand its physiological function in skeletal muscle. | Lin Kang Chunmiao Han Guangyan Yang Hu Li Tingting Li Shu Yang Na Liang Ran Zhong Lijing Jia Dahai Zhu Yong Zhang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，8： | 0 |
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