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| 1 | STUDY OF CAPILLARY ELECTROPHORESIS ON MICROCHIP BASED ON MEMS显示文摘Using a standard photolithographical procedure, chemical wet etching and thermal diffusion bonding technology, a chemical analysis device for Capillary Electrophoresis(CE) has been microfabricated on a planar glass substrate with a cross-column geometry. The channels on the microchip substrate are about 50μm deep and 150μm wide. By employing amino acids derived from 2,4-DiNitroFluoroBenzen (DNFB) on CE chip channels, the sample manipulating system is studied based on the principle of electrodynamics. | Wang Ming Li Wei Han Jinghong Cui Dafu (State Key Lab. of Transducer Tech., Inst. of Electron., Chinese Academy of Sci., Beijing 100080) | 2002 | Journal of Electronics(China)2002，19，4： | 1 |
| 2 | Review:A Survey of Single Gimbal Control Moment Gyroscope forAgile Spacecraft Attitude Control显示文摘Agile attitude maneuver is a basic requirement for next generation imaging spacecraft and Control Moment Gyroscope (CMG) is an effective candidate for large space station and agile spacecraft attitude control because of its torque amplification capability. This paper provides a thorough survey of Single Gimbal Control Moment Gyroscope (SGCMG) in terms of configuration,evaluation,modeling,singularity analysis and steering logic,etc. For specific space missions,CMGs are logically mounted into different particular arrays which can be chosen by the proposed evaluation methods. From the dynamic model we find a tough inverse mapping problem which suffers the inherent geometric singularity. Different techniques and theories then are applied for singularity analysis and CMG steering logics design. The pyramid CMG cluster and singular robust logics are proven to be able to enhance the agility of spacecraft. Above work forms a systematic framework of SGCMG for agile spacecraft control with lots of illustrative examples,tables and figures,and will evoke further investigation for future missions. | Yunhua Wu Feng Han Bing Hua Zhiming Chen Dafu Xu Linlin Ge | 2018 | Journal of Harbin Institute of Technology(New Series)2018，25，6： | 1 |
| 3 | Energy minimization method for scattered data hermite interpolation显示文摘 | Zhou Tianhe Han Dafu Lai Mingjun | 2008 | Applied Numerical Mathematics2008，58，： | 1 |
| 4 | Immunomodulation and osseointegration activities of Na_(2)TiO_(3) nanorods-arrayed coatings doped with different Sr content显示文摘To endow Ti-based orthopedic implants immunomodulatory capability and thus enhanced osseointegration,different amounts of Sr are doped in Na_(2)TiO_(3) nanorods in the arrays with identical nanotopographic parameters(rod diameter,length and inter-rod spacing)by substitution of Na^(+) using hydrothermal treatment.The obtained arrays are denoted as STSr2,STSr4,and STSr7,where the arabic numbers indicate the incorporating amounts of Sr in Na_(2)TiO_(3).The modulation effects of the Sr-doped nanorods arrays on macrophage polarization and osteogenetic functions of osteoblasts are investigated,together with the array without Sr(ST).Moreover,osseointegration of these arrays are also assayed in rat femoral condyles.Sr-doped nanorods arrays accelerate M1(pro-inflammatory phenotype)-to-M2(anti-inflammatory phenotype)transformation of the adhered macrophages,enhancing secretion of pro-osteogenetic cytokines and growth factors(TGF-β1 and BMP2),moreover,the Sr doped arrays directly enhance osteogenetic functions of osteoblasts.The enhancement of paracrine of M2 macrophages and osteogenetic function of osteoblasts is promoted with the increase of Sr incorporating amounts.Consequently,Sr doped arrays show significantly enhanced osseointegration in vivo compared to ST,and STSr7 exhibits the best performance.Our work sheds a new light on the design of surface chemical components and structures for orthopedic implants to enhance their osseointegration. | Dongmei Yu Shuo Guo Meng Yu Wenwen Liu Xiaokang Li Dafu Chen Bo Li Zheng Guo Yong Han | 2022 | Bioactive Materials2022，7，4： | 1 |
| 5 | Eco-friendly bacteria-killing by nanorods through mechano-puncture with top selectivity显示文摘Nanorods can induce mechano-puncture of Staphylococcus aureus(S.aureus)that often impairs osseointegration of orthopedic implants,while the critical nanorod top sharpness able to puncture S.aureus and the predominant contributor between top sharpness and length to mechano-puncture activity remains elusive.Herein,we fabricated three kinds of Al2O3-wrapped nanorods patterned arrays with different lengths and top sharpness.The top-sharp nanorods have lengths of 469 and 884 nm and the shorter show a length identical to the top-flat nanorods.Driven by the equivalent adhesive force of S.aureus,the top-flat nanorods deform cell envelops,showing a bacteriostatic rate of 29%owing to proliferation-inhibited manner.The top-sharp nanorods puncture S.aureus,showing a bactericidal rate of 96%for the longer,and 98%for the shorter that simultaneously exhibits fair osseointegration in bacteria-infected rat tibias,identifying top sharpness as a predominate contributor to mechano-puncture activity.Based on finite-element simulation,such top-flat nanorod derives the maximum stress(Smax)of 5.65 MPa on cell wall,lower than its ultimate-tensile-strength(13 MPa);while such top-sharp and shorter nanorod derives Smax of 20.15 MPa to puncture cell envelop.Moreover,a critical top conical angle of 138◦is identified for nanorods able to puncture S.aureus. | Jing Ye Bo Li Yufeng Zheng Shuilin Wu Dafu Chen Yong Han | 2022 | Bioactive Materials2022，7，9： | 0 |
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