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955篇 您的检索式:作者名="Hamilton M J"
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1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2An integrated anal ytical approach for determining the origin of solid bitumens in the McArthur Basin,Northern Australia显示文摘George S C Llorca S M Hamilton P J 1994Org Geochem1994,21,:1
3Colorimetric method for determination of sugars and related substances显示文摘Dubois M Gilles K A Hamilton J K 1956Anal Chem1956,28,:1
4Phytoremediation of soil contaminated with low concentrations of radionuclides显示文摘Entry J A Vance N C Hamilton M A 1996Water Air Soil Pollution1996,88,:1
5The effect of published reports of unethical conduct on stock prices显示文摘RAO S M HAMILTON J B 1996Journal of Business Ethics1996,,12:1
6The impact of R&D intensity on demand for specialist auditor services 显示文摘Godfrey M Hamilton J 2005Contem- porary Accounting Research2005,22,1:1
7Colorimedic method for determination of sugars and related subetances 显示文摘Dubois M GlUes K A Hamilton J K etal 1956Analytical Chemistry1956,28,3:1
8Neonatal porcine Sertoli cells inhibit human natural antibody -mediated lysis显示文摘DUFOUR J M HAMILTON M RAJOTTE R V 2005Biol Reprod2005,72,5:1
9Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R 2009Journal of Bacteriology2009,191,16:1
10Colorimetric method for determination of sugars and related substances 显示文摘Dubois M Gilles K A Hamilton J K 1956Analytical chemistry1956,28,3:1
11Feline ilial fractures:a prospective study of dorsal plating and comparisonwith lateral plating显示文摘Langley-Hobbs S J Meeson R L Hamilton M H 2009Vet Surg2009,38,:1
12Organic polymer thin-film transistor photosensors 显示文摘Hamilton M C Kanicki J 2004IEEE J Sel Top Quantum Electron2004,10,4:1
13Beta blocker and angiotensin-converting enzyme inhibitor therapy is associated with decreased Th1/Th2 cytokine ratios and inflammatory cytokine production in patients with chronic heart failure 显示文摘Gage J R Fonarow G Hamilton M 2004Neuroimmunomodulation2004,11,3:1
14Excess of nonparental bands in offspring from known pedigrees assayed using RAPD PCR显示文摘Reidy M F Hamilton W J Aquadro C F 1992Nucleic Acids Res1992,20,:1
15Colorimetric methods for determination of sugars and related substances 显示文摘DOBOIS M A HAMILTON J K REBERS P A 1956Analytical Chemistry1956,28,3:1
16Genetic manipulation of lignin reduces recalcitrance and improves ethanol production from switchgrass 显示文摘Fu C Mielenz JR Xiao X Ge Y hamilton CY Rodriguez M Chen F Foston M Ragauskas A Bouton J Dixon RA Wang ZY 2011Proc Natl Acad Sci USA2011,108,9:1
17Feline ilial fractures:assessment of screw loosening and pelvic canal narrowingafter lateral plating显示文摘Hamilton M H Evans D A Langley-Hobbs S J 2009Vet Surg2009,38,:1
18Colorimetricmethod for determination of sugars and related substances显示文摘Dubois M Gilles K A Hamilton J K 1956Anal Biochem?1956,3,28:1
19Colori- metric method for determination of sugars and related sub- stances 显示文摘DUBOIS M GILLES K A HAMILTON J K 1956Analytical Chemistry1956,28,3:1
20Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection 显示文摘Hamilton M J Weingarden AR Sadowsky M J 2012Am J Gastroenterol2012,107,5:1
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