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| 1 | Marked elevation of B-type natriuretic peptide in patients with heart failure and preserved ejection fraction显示文摘Marked elevations of B-type natriuretic peptide(BNP)are not generally seen in patients with heart failure and preserved ejection fraction(HFpEF).The objective of this study was to examine the clinical and laboratory characteristics of a large cohort of patients with HFpEF and markedly elevated BNP.A retrospective examination of 421inpatients at a university hospital admitted with a diagnosis of HFpEF was performed.Clinical and echocardiographic data in 4 groups of patients with levels of BNP≤100 pg/mL,100-400 pg/mL,400-1,000 pg/mL and>1,000 pg/mL were compared.Patients with HFpEF and BNP>1,000 pg/mL(28%of the population)were characterized by impaired renal function and greater use of anti-hypertensive medications.A subset of these patients with BNP>1,000 pg/mL had normal renal function(21%)and were significantly older,more frequently female,and tended to have lower ejection fractions.Conversely,patients with HFpEF and BNP≤100 pg/mL were younger and had preserved renal function.BNP was inversely related to the likelihood of subsequent admission for heart failure,but not to myocardial infarction or death.In conclusion:BNP>1,000 pg/mL is seen in almost 1/3 of patients hospitalized with HFpEF.This elevation of BNP often reflects impaired renal function,but can also be seen in patients with preserved renal function but relatively impaired systolic function. | Samuel Tate Andrea Griem Blythe Durbin-Johnson Clifton Watt Saul Schaefer | 2014 | The Journal of Biomedical Research2014，28，4： | 7 |
| 2 | Studies on epidemiology and pathogenicity of porcine circovirus显示文摘 | Ilse Tischer W. Mields D. Wolff M. Vagt W. Griem | 1986 | Archives of Virology (-)1986，，3： | 3 |
| 3 | Three-dimensional photon dosimetry:a comparison of treatment of the intact breast in the supine and prone position显示文摘 | Griem KL Fetherston P Kuznetsova M | 2003 | Int J Radiat Oncol Biol Phys2003，57，3： | 1 |
| 4 | Concomitant eisplatin/5-FU infusion and radiotherapy in advanced head and neck cancer: 8-year analysis of results 显示文摘 | Taylor S G 4th Murthy A K Griem K L | 1997 | Head Neck1997，19，8： | 1 |
| 5 | A New Procedure for the Prediction of Forced Convection Heat Transfer at Nearand Supercritical Pressure显示文摘 | Griem H | 1996 | Heat and Mass Transfer1996，31，5： | 1 |
| 6 | A New Procedure for the Prediction of Forced Convection Heat Transfer at Near and Supercritical Pressure显示文摘 | Griem H | 1996 | Heat and Mass Transfer1996，31，： | 1 |
| 7 | A New Procedure for the Prediction of Forced Convection Heat Transfer at Near-and Supercritical Pres- sure 显示文摘 | Griem H | 1996 | Heat and Mass Transfer1996，31，5： | 1 |
| 8 | High-resolution measurement of electroon velocity distribution functions in a plasment显示文摘 | Maffei K C Griem H R | 1985 | Phys Fluids1985，28，10： | 1 |
| 9 | Three-dimensional photon dosimetry:a comparison of treatment of the intact breast in the supine and prone position显示文摘 | Griem KL Fetherston P Kuznetsova M | 2003 | Int J Radiat Oncol Biol Phys2003，57，3： | 1 |
| 10 | Toxicity and ecotoxicity of sulfonic-acids:structure-activity relationship 显示文摘 | Griem H Ahlers J Bias R | 1994 | Chemosphere1994，28，12： | 1 |
| 11 | A new procedure for the prediction of forced convection heat transfer at near-and su- percritical pressure显示文摘 | GRIEM H | 1996 | Heat and Mass Trans- fer1996，31，5： | 1 |
| 12 | An expedient and multikilogram synthesis ofa naphthalenoid Hs antagonist 显示文摘 | Pu YM Ku YY Grieme T | 2007 | Org Process Res Dev2007，11，6： | 1 |
| 13 | Three dimensional photon dosimetry:a comparison of treatment of the intact breast in the supine and prone position显示文摘 | Griem KL Fetherston P Kuznetsova M | | 0，，03： | 1 |
| 14 | Studies on epidemiology and pathogenicity of porcine circovirus显示文摘 | Ilse Tischer W. Mields D. Wolff M. Vagt W. Griem | 1986 | Archives of Virology (-)1986，，3： | 1 |
| 15 | Stark Broadening of Isolated Spectral Lines from Heavy Elements in a plasma显示文摘 | Griem H R | 1962 | Phys Rev1962，128，： | 1 |
| 16 | Tomotherapy and Multifield Intensity-Modulated Radiotherapy Planning Reduce Cardiac Doses in Left-Sided Breast Cancer Patients With Unfavorable Cardiac Anatomy显示文摘 | Alan B. Coon Adam Dickler Michael C. Kirk Yixiang Liao Anand P. Shah Jonathan B. Strauss Sea Chen Julius Turian Katherine L. Griem | 2010 | International Journal of Radiation Oncology, Biology, Physics2010，，1： | 1 |
| 17 | Should multicentric disease be an absolute contraindication to the use of breast conserving therapy?显示文摘 | Hartsell WF Recine DC Griem KL | 1994 | Int J Radiat Oncol Biol Phys1994，30，： | 1 |
| 18 | Enamel fluoride uptake of a novel water-based fluoride varnish显示文摘 | Attin T Grieme R Hannig C | 2005 | Arch Oral Biol2005，50，3： | 1 |
| 19 | A facile and scaleable synthesis of ABT-239,a benzofuranoid H3 antagonist显示文摘 | Pu YM Grieme T Gupta A | 2005 | Org Process Res Dev2005，9，1： | 1 |
| 20 | Electron density measurement using the Stark profiles of Al lines显示文摘 | Dalta R U Griem H R | 1979 | Phys Fluids1979，22，7： | 1 |
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