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| 1 | Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease显示文摘Intrahepatic fat deposition has been demonstrated in patients with nonalcoholic fatty liver disease(NAFLD). Genetic and environmental factors are important for the development of NAFLD. Diseases such as obesity, diabetes, and hypertension have been found to be closely associated with the incidence of NAFLD. Evi-dence suggests that obesity and insulin resistance are the major factors that contribute to the development of NAFLD. In comparing the factors that contribute to the buildup of excess calories in obesity, an imbalance of energy homeostasis can be considered as the basis. Among the peripheral signals that are generated to regulate the uptake of food, signals from adipose tissue are of major relevance and involve the maintenance of energy homeostasis through processes such as lipo-genesis, lipolysis, and oxidation of fatty acids. Advances in research on adipose tissue suggest an integral role played by adipokines in NAFLD. Cytokines secreted by adipocytes, such as tumor necrosis factor-α, transform-ing growth factor-β, and interleukin-6, are implicated in NAFLD. Other adipokines, such as leptin and adiponectin and, to a lesser extent, resistin and retinol binding protein-4 are also involved. Leptin and adiponectin can augment the oxidation of fatty acid in liver by activating the nuclear receptor super-family of transcription fac-tors, namely peroxisome proliferator-activated receptor(PPAR)-α. Recent studies have proposed downregula-tion of PPAR-α in cases of hepatic steatosis. This re-view discusses the role of adipokines and PPARs with regard to hepatic energy metabolism and progression of NAFLD. | Vettickattuparambil George Giby Thekkuttuparambil Ananthanarayanan Ajith | 2014 | World Journal of Hepatology2014，6，8： | 30 |
| 2 | Crosslinking of interfacial layers in multilayered oil-in-water emulsions using laccase:Characterization and p H-stability显示文摘 | Zeeb B Gibis M Fischer L | 2012 | Food Hydrocolloid2012，27，1： | 1 |
| 3 | Effect of oil marinades with garlic,onion,and lemon juice on the formation of heterocyclic aromatic amines in fried beef patties显示文摘 | Gibis M | | 0，，25： | 1 |
| 4 | Combustibledust:A serious industrial hazard显示文摘 | Giby Joseph CSB Hazard Investigation Team | 2007 | Journal of HazardousMaterials2007，142，3： | 1 |
| 5 | VEGFR2 predicts decreased patients survival in soft tissue sarcomas显示文摘 | Kampmann E Altendorf-Hofmann A Gibis S | 2015 | Pathol Res Pract2015，211，10： | 1 |
| 6 | Inhibitory effect of marinades with Hibiscus extract on formation ofheterocyclic aromatic amines and sensory quality of fried beef patties显示文摘 | GIBIS M WEISS J | 2010 | Meat Science2010，85，4： | 1 |
| 7 | Effect ofoil marinades with garlic, onion, and lemon juice on the lbrmation of heterocyclic aromatic amines in fried beef patties显示文摘 | GIBIS M | 2007 | Journal of Agricultural and Food Chemistry2007，55，10： | 1 |
| 8 | Combustible dusts :A serious industrial hazard 显示文摘 | Giby J CSB Hazard Investigation Team | 2007 | Journal of Hazardous Materials2007，142，3： | 1 |
| 9 | Antioxidant capacity and inhibitory effect of grape seed and rosemary extract in marinades on the formation of heterocyclic amines in fried beef patties 显示文摘 | Gibis M Weiss J | 2012 | Food Chemistry2012，134，2： | 1 |
| 10 | Advances in ingre- dient and processing systems for meat and meat products 显示文摘 | Weiss J Gibis M Schuh V etal | 2010 | Meat Science2010，86，1： | 1 |
| 11 | The effects of hypoxia is chemic on expression of c -fos, C- Jun and HSP70 in the young rat hippocam Pus显示文摘 | Giby KL | 1977 | Brain Res1977，48，1： | 1 |
| 12 | Advances in ingredient and processing systems for meat and meat products显示文摘 | WEISS J GIBIS M SCHUH V | 2010 | Meat Science2010，86，1： | 1 |
| 13 | Combustible dusts: a serious industrial hazard 显示文摘 | Giby Joseph CSB Hazard Investigation Team | 2007 | Journal of Hazardous Materials2007，142，3： | 1 |
| 14 | combustible dusts: A serious industrial hazard显示文摘 | Giby Joseph CSB hazard investigation team | 2007 | Journal of Hazardous Materials2007，142，3： | 1 |
| 15 | Impact of Precursors Creatine,Creatinine,and glucose on the formation of heterocyclic aromatic amines in grilled patties of various animal species显示文摘 | GIBIS M WEISS J | 2015 | Journal of Food Science2015，80，11： | 1 |
| 16 | Formation, characterization, and stability of encapsulated hibiscus extract in multilayered liposomes 显示文摘 | Gibis M Zeeb B Weiss J | 2014 | Food Hydrocolloids2014，38，0： | 1 |
| 17 | A short history of health technology assessment in Germany 显示文摘 | Matthias Perleth Bernhard Gibis Britta Gohlen | 2009 | International Journal of Technology Assessment in Health Care2009，25，1： | 1 |
| 18 | Influence of Interfacial Properties on Ostwald Ripening in linked Muhilayered Oil-in-Water Emulsions显示文摘 | Zeeb Benjamin Gibis Monika Fischer Lutz | 2012 | Journal of Colloid and Interface Science2012，387，： | 1 |
| 19 | Activities and participation in young adults with osteogenesis i mperfecta显示文摘 | Montpetit K Dahan- Oliel N Ruck- Gibis J | 2011 | J Pediatr Rehabil Med2011，4，1： | 1 |
| 20 | Formation, characterization, and stability of encapsulated hibiscus extract in multilayered liposomes 显示文摘 | Gibis M Zeeb B Weiss J | 2014 | Food Hydrocolloids2014，38，： | 1 |
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