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| 1 | Percutaneous left atrial appendage closure:Technical aspects and prevention of periprocedural complications with the watchman device显示文摘Transcatheter closure of the left atrial appendage has been developed as an alternative to chronic oral anticoagulation for stroke prevention in patients with atrial fibrillation, and as a primary therapy for patients with contraindications to chronic oral anticoagulation. The promise of this new intervention compared with warfarin has been supported by several, small studies and two pivotal randomized trial with the Watchman Device. The results regarding risk reduction for stroke have been favourable although acute complications were not infrequent. Procedural complications, which are mainly related to transseptal puncture and device implantation, include air embolism, pericardial effusions/tamponade and device embolization. Knowledge of nature, management and prevention of complications should minimize the risk of complications and allow transcatheter left atrial appendage closure to emerge as a therapeutic option for patients with atrial fibrillation at risk for cardioembolic stroke. | Sven M bius-Winkler Nicolas Majunke Marcus Sandri Norman Mangner Axel Linke Gregg W Stone Ingo D hnert Gerhard Schuler Peter B Sick | 2015 | World Journal of Cardiology2015，7，2： | 14 |
| 2 | A concise, practical guide to diagnostic assessment for mast cell activation disease显示文摘As recognition of mast cell(MC) involvement in a range of chronic inflammatory disorders has increased, diagnosticians' suspicions of MC activation disease(MCAD) in their chronically mysteriously inflamed patients have similarly increased. It is now understood that the various forms of systemic mastocytosis- diseases of inappropriate activation and proliferation of MCs seemingly driven by a small set of rare, usually constitutively activating mutations in assorted MC regulatory elements-comprise merely the tip of the MCAD iceberg, whereas the far larger and far more clinically heterogeneous(and thus more difficult to recognize) bulk of the iceberg consists of assorted forms of MC activation syndrome(MCAS) which manifest little to no abnormal MC proliferation and may originate from a far more heterogeneous set of MC mutations. It is reasonable to suspect MCAD when symptoms and signs of MC activation are present and no other diagnosis better accounting for the full range of findings is present. Initial laboratory assessment should include not only routine blood counts and serum chemistries but also a serum total tryptase level, which helps direct further evaluation for mastocytosis vs MCAS. Appropriate tissue examinations are needed to diagnose mastocytosis, while elevated levels of relatively specific mast cell mediators are sought to support diagnosis of MCAS. Whether assessing for mastocytosis or MCAS, testing is fraught with potential pitfalls which can easily yield false negatives leading to erroneous rejection of diagnostic consideration of MCAD in spite of a clinical history highly consistent with MCAD. Efforts at accurate diagnosis of MCAD are worthwhile, as many patients then respond well to appropriately directed therapeutic efforts. | Lawrence B Afrin Gerhard J Molderings | 2014 | World Journal of Hematology2014，3，1： | 3 |
| 3 | The induction of ovulation with pulsatile GnRH administration in hyperandrogenic woman after down -regulation with buserelin or suppression with a oral contraceptive 显示文摘 | Gerhard I Matthes J Runncbaum B | 1993 | HumReprod1993，8，： | 1 |
| 4 | Biological properties of es-sential oils : An updated review 显示文摘 | BARBARA A GERHARD B | 2010 | Flavour Frag J2010，25，6： | 1 |
| 5 | Novel rhodium complexes with ferroeene-based N-heterocylic carbenes: Synthesis, structure and catalysis显示文摘 | YU Y GERHARD R CARSTEN B | 2005 | Journal of OrganometalIic Chemistry2005，690，： | 1 |
| 6 | Auricular Acupuncture with Laser 显示文摘 | Regina R Gerhard L Frank B | 2013 | Evid Based Complement Ahernat Med2013，2013，98： | 1 |
| 7 | Postoperative analgesia after knee surgery:a comparison of three different concentrations of ropivacaine for continuous femoral nerve blockade显示文摘 | Gerhard B Hartmut B Hugo VA | 2007 | Anesth Analg2007，105，1： | 1 |
| 8 | Air-water gas transfer in uniform channel flow显示文摘 | Douglas B M Gerhard H J | 1999 | Journal of hydraulic engineering1999，125，1： | 1 |
| 9 | Oxidative stress, mitochondrial permeability transition and cell death in Cu exposed trouthepatocytes显示文摘 | Gerhard K ClaudiaM Christian B | 2005 | Toxicol Appl Phar macol2005，20，962： | 1 |
| 10 | Parameter and process significance in mechanistic modeling of cellulose hydrolysis显示文摘 | Rotter B E Barry D A Gerhard J I Small J S | 2009 | Bioresource Technol2009，99，13： | 1 |
| 11 | Cyclodextrin rotaxanes and polyrotaxanes显示文摘 | Gerhard W Han B H Axel M | 2006 | Chemical Reviews2006，106，： | 1 |
| 12 | Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2 microglobulin deficient NOD/SCID mice transgenic for human growth factors显示文摘 | Feuring-Buske M Gerhard B Cashman J | 2003 | Leukemia2003，17，4： | 1 |
| 13 | Composition quality control and antmicrobial activity of the essential oil of long-time Dill seeds from Bulgaria显示文摘 | LEOPOLD J GERHARD B ALBERA S | 2003 | Chemistry of Natural Compounds2003，51，： | 1 |
| 14 | The efficacy ofdiphtheria-growth factor fusion proteins is enhanced by co-adminis-tration of cytosine arabinoside in an immunodeficient mouse modelof human acute myeloid leukemia 显示文摘 | Hogge DE Feuring-Buske M Gerhard B | 2004 | Leuk Res2004，28，11： | 1 |
| 15 | Detection, isolation, and stimulation of quiescent primitive leukemic progenitur cells from palients with acute myeloid leukemia (AML) 显示文摘 | Guan Y Gerhard B Hogge DE | 2003 | Blood2003，101，8： | 1 |
| 16 | Impact of conization type on the resected cone volume : results of a retrospective multi-center study显示文摘 | Christoph G Lindsay B Gerhard S | 2013 | Arch Gynecol Obstet2013，288，5： | 1 |
| 17 | Rapid simultaneous determination of major type A-and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry显示文摘 | FRANZ B RAINER S GERHARD B | 2005 | Journal of Chromatography A2005，1062，： | 1 |
| 18 | Low-cost HARMS process 显示文摘 | Roger B Heinrich Z Gerhard S | 1997 | Sensors and Actuators A1997，61，： | 1 |
| 19 | High-pressure solubility of 1 , 4-bis-( n-alkylamino ) -9,10-anthraquinones in near-and supercritical carbon dioxide显示文摘 | Cornelia B Kautz Bjorn Wagner Gerhard M Schneider | 1998 | Journal of Supercritical Fluids1998，13，： | 1 |
| 20 | The influence of waterflood design on the recovery of mobile DNAPLs显示文摘 | GERHARD J I KUEPER B H HECOX G R | 1998 | Groundwater1998，36，2： | 1 |
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