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| 1 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 2 | Effects of Lactoba-cillus acidophilus D2/CSL on laying hen performance显示文摘 | Gallazzi D Giardini A Mangiagalli M G | 2008 | Ital J An- im Sci2008，7，1： | 1 |
| 3 | Treatment of benign nodular goiter with mildly suppressive doses of L-thyroxine : effects on bone mineral density and on nodule size 显示文摘 | Baldini M Gallazzi M Orsatti A | 2002 | J Intern Med2002，251，5： | 1 |
| 4 | Molecular imaging of bcl-2 expression in small lymphocytic lymphoma using 111In-labeled PNA-peptide conjugates显示文摘 | Jia F Figueroa SD Gallazzi F | 2008 | J Nucl Med2008，49，： | 1 |
| 5 | 111In-labeled lactam bridge-cyclized α-melanocyte stimulating hormone peptide analogues for melanoma imaging显示文摘 | Miao Y B Gallazzi F Guo H X | 2008 | Bioconjugate Chemistry2008，19，2： | 1 |
| 6 | Effect of DOTA position on melanoma targeting and pharmacokinetic properties of111In-labeled lactam bridge-cyclized α-melanocyte stimulating hormone peptide显示文摘 | Guo H X Yang J Q Gallazzi F | 2009 | Bioconjugate Chemistry2009，20，11： | 1 |
| 7 | Effects of the amino acid linkers on melanoma-targeting and pharmacokinetic properties ofIndium-111-labeled lactam bridge-cyclized α-MSH peptides显示文摘 | Guo H Yang J Gallazzi F | 2011 | Journal of Nuclear Medicine2011，52，4： | 1 |
| 8 | Gallium-67-labeled lactam bridge-cyclized alpha-MSH peptides with enhanced melanoma uptake and reduced renal uptake显示文摘 | Guo H X Gallazzi F Miao Y B | 2012 | Bioconjugate Chemistry2012，23，6： | 1 |
| 9 | Radiometal-labeled peptide- PNA conjugates for targeting bcl-2 expression: preparation, characterization, and in vitro mRNA binding显示文摘 | Lewis MR Jia F Gallazzi F | 2002 | Bioconjug Chem2002，13，6： | 1 |
| 10 | Gallium-67-labeled lactam bridge-cyclized alpha-MSH peptides with enhanced melanoma uptake and reduced renal uptake显示文摘 | Guo H Gallazzi F Miao Y | 2012 | Bioconjugate chemistry2012，23，6： | 1 |
| 11 | Reduction of the ring size of radiolabeled lactam bridge-cyclized alpha-MSH peptide resulting in enhanced melanoma uptake显示文摘 | Guo H Yang J Gallazzi F | 2010 | Journal of Nuclear Medicine2010，51，3： | 1 |
| 12 | Desflurane preconditioning in coronary artery bypass graft surgery:a double-blinded,randomised and placebo-controlled study显示文摘 | Meco M Cirri S Gallazzi C | 2007 | Eur J Cardiothorac Surg2007，32，2： | 1 |
| 13 | Surgical treatment of synchronous multiple lung cancer located in a different lobe or lung: high survival in node-negative subgroup ☆显示文摘 | Luca Voltolini Cristian Rapicetta Luca Luzzi Claudia Ghiribelli Piero Paladini Felice Granato Mariasole Gallazzi Giuseppe Gotti | 2010 | European Journal of Cardio-Thoracic Surgery2010，，5： | 1 |
| 14 | Desflurane preconditioning in coronary artery bypass graft surgery : a double - blinded, randomised and placebo- controlled study显示文摘 | MECO M CIRRI S GALLAZZI C | 2007 | Eur J Cardiothorae Surg2007，32，2： | 1 |
| 15 | The role of diagnostic imaging in synovial sarcoma: our experience显示文摘 | Marzano L Failoni S Gallazzi M Garbagna P | 2004 | Radiol Med (Torino)2004，107，： | 1 |
| 16 | Synthesis of rsdiometal-labeled and fluorescent cell-permeating peptide-PNA conjugates for targeting the bcl-2proto-oncogene显示文摘 | Gallazzi F Wang Y Jia F | 2003 | Bioconjug Chem2003，6，： | 1 |
| 17 | The ages and metallieities of galaxies in the local uni-verse显示文摘 | GALLAZZI A CHARLOT S BRINCHMANN J ct al | 2005 | Monthly Notices of the Royal Astronomical Soci-ety2005，362，： | 1 |
| 18 | Desflurane preconditioning in coronary artery bypass graft surgery:a double-blinded,randomised and placebo-controlled study显示文摘 | Massimo Meco Silvia Cirri Chiara Gallazzi Giulia Magnani | 2007 | European Journal of Cardio-Thoracic Surgery2007，32，： | 1 |
| 19 | Calcific tendinitis of the rectus femoris:a rare cause of snapping hip显示文摘 | Pierannunzii L Tramontana F Gallazzi M | | 0，，： | 1 |
| 20 | Desflurane preconditioning in coronary artery bypass graft surgery: a double-blind, randomized and placebo-c- ontrolled study显示文摘 | Meco M Cirri S Gallazzi C | 2007 | Eur J Cardiothorae Surg2007，32，： | 1 |
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