|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 蚯蚓(Eiseniafetida)细胞色素P450及抗氧化酶系对环境浓度苯并(a)芘的响应显示文摘以赤子爱胜蚓(Eisenia fetida)为供试生物,草甸棕壤为供试土壤,以蚯蚓微粒体细胞色素P450含量、抗氧化酶系以及谷胱甘肽转移酶活性为指标,进行了土壤中苯并(a)芘[B(a)P]暴露与酶活性的量-效关系研究。结果表明,在接近沈抚灌区实地污染状况B(a)P(0.1~2.0mg.kg-1)暴露下,第1、3、7以及第14d取样时,P450和SOD有较好的响应:SOD在第1、3d显著升高,而在第7、14d时降低;P450总体表现为低浓度B(a)P诱导下降低,高浓度下升高的趋势。CAT、POD以及GST的敏感性相对较差。比照其他4个指标,蚯蚓P450的敏感性更为优异,具有较好的应用前景。指标敏感性总体表现为:P450>SOD>CAT/POD>GST。 | 王磊 宋玉芳 张薇 陈朗 David Freestone M Leigh Ackland | 2009 | 农业环境科学学报2009，28，2： | 12 |
| 2 | 植物CytP450和抗氧化酶对土壤菲、芘暴露的生态毒理响应显示文摘以玉米(ZeamaysL.)为供试植物,草甸棕壤为供试土壤,以微粒体细胞色素P450含量、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和过氧化物酶(POD)活性为指标,进行了土壤菲、芘暴露的生态毒理响应研究.结果表明,菲、芘暴露均能引起植物代谢解毒和抗氧化防御系统的胁迫响应,不同程度引发植物代谢解毒及抗氧化能力的改变.P450酶活性与低浓度菲、芘单一暴露浓度具有相关性(r=0.834,p<0.01),与菲、芘复合暴露浓度负相关,说明菲、芘复合暴露导致代谢解毒能力下降,对植物的代谢解毒具有协同毒性效应;SOD酶活性与菲、芘单一暴露浓度负相关,CAT酶活性与菲、芘单一暴露浓度正相关,POD酶活性与菲的水溶解度正相关,而与芘的总浓度负相关.SOD、CAT和POD酶活性与菲、芘复合暴露浓度均呈正相关,说明菲、芘复合暴露导致氧化损伤程度减弱,对植物的氧化损伤具有拮抗作用. | 宋玉芳 王磊 李昕馨 张薇 陈朗 Freestone David 吉普辉 Ackland M Leigh | 2009 | 环境科学学报2009，29，2： | 9 |
| 3 | Metabolic modulation with perhexiline in chronic heart failure - a randomized, controlled trim of short - term use of a novel treatment 显示文摘 | Lee L Campbell R Scheuermann - Freestone M et al | 2005 | Circulation2005，112，： | 1 |
| 4 | A new model of congestive heart failure in the mouse due to chron-ic volume overload 显示文摘 | Scheuermann-Freestone M Freestone N S Langenickel T | 2001 | EurJ Heart Fail2001，3，5： | 1 |
| 5 | A new model of congestive heart failure in the mouse due to chronic volume overload显示文摘 | Scheuermann-Freestone M Freestone NS Langenickel T | 2001 | Eur J Heart Fail2001，3，5： | 1 |
| 6 | Design of a phase-sensitive detector to maximize signal-to-noise ratio in the presence of Gaussian wideband noise 显示文摘 | Smith R W M Freeston I L Brown B H | 1992 | Meas Sci Technol1992，3，11： | 1 |
| 7 | The universal stress pro- tein, UspA, of Escherichia coli is phosphorylated in response to sta- sis 显示文摘 | Freestone P Nystrom T Trinei M | 1997 | Journal of Molecular Biology1997，274，： | 1 |
| 8 | Motivations of the ethical consumer显示文摘 | FREESTONE 0 M MCGOLDRICK P J | 2008 | Journal of Business Ethics2008，79，4： | 1 |
| 9 | A real-time electrical impedance tomography system for clinical use-design and prehminary results 显示文摘 | SMITH R W M FREESTON L L BROWN B H | 1995 | IEEE Trans on Biomed Eng1995，43，： | 1 |
| 10 | Why do people worry?显示文摘 | Freeston M H Rheaume J Letarte H | 1994 | Personality and Individual Differences1994，17，6： | 1 |
| 11 | The universal stress protein, UspA, of Escherichia coli is phosphorylated in response to stasis显示文摘 | Freestone P Nystrom T Trinei M | 1997 | J Mol Biol1997，274，3： | 1 |
| 12 | Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes显示文摘 | Lyte M Freestone PP Neal CP | | 0，，9352： | 1 |
| 13 | Functional and dysfunctional perfectionists:are they different on compulsive-like behaviors显示文摘 | Rhe'aume J Freeston M H Ladouceur R Boucard C Gallant L Talbot F Vallie'res A | 2000 | Behavior Research and Therapy2000，38，： | 1 |
| 14 | Sleep apnoea is associated with impaired cardiac high energy phosphate metabolism and abnomal diastolic function 显示文摘 | Scheuermannz Freestone M West S Waston G | 2006 | Heart2006，5，922： | 1 |
| 15 | Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-in- duced sepsis显示文摘 | Freestone PP Williams PH Haigh RD Maggs AF Neal CP Lyte M | 2002 | Shock2002，18，5： | 1 |
| 16 | The prediction of obsessive- compulsive tendencies: does perfectionism play a significant role 显示文摘 | Rheaume J Ladouceur R Freeston M | 2000 | Pers Individ Dif2000，28，3： | 1 |
| 17 | Functional and dysfunctional perfectionists:are they different on compulsive-like behaviors显示文摘 | Rhe aume J Freeston M H Ladouceur R | 2000 | Behavior Research and Therapy2000，38，： | 1 |
| 18 | A new model of congestive heart failure in the mouse due to chronic volume overload显示文摘 | Scheuermann-Freestone M Freestone SN Langenickel T | 2001 | Eur J Heart Fail2001，3，5： | 1 |
| 19 | The prediction of obsessivecompulsive tendencies: Does perfectionism play a significant role 显示文摘 | Rheaume J Ladoueeur R Freeston M | 2000 | Personality and Individual Differences2000，28，3： | 1 |
| 20 | Sildenafil citrate and blood pressure lowering drugs:results of drug interaction studies with an organic nitrate and a calcium antagonist显示文摘 | Webb DJ Freestone S Allen M J | 1999 | Am J Cardiol1999，83，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员