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您的检索式：作者名="Francesco Claps"
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| 1 | Reliability of nephrolithometric nomograms in patients treated with minimally invasive percutaneous nephrolithotomy: A precision study显示文摘Objectives:The study aimed to evaluate quality of nephrolithometric nomograms to predict stone-free rates(SFRs)and complication rates(CRs)in case of minimally invasive percutaneous nephrolithotomy(PNL).In the last decade,nomograms have been introduced to estimate the SFRs and CRs of PNL.However,no data are available regarding their reliability in case of utilization of miniaturized devices.Herein we present a prospective multicentric study to evaluate reliability of Guy’s stone score(GSS),the stone size,tract length,obstruction,number of involved calyces,and essence of stone(S.T.O.N.E.)nephrolithometry score and Clinical Research Office of the Endourological Society(CROES)score in patients treated with minimally invasive PNL.Methods:We evaluated SFRs and CRs of 222 adult patients treated with miniaturized PNL.Patients were considered stone-free if no residual fragments of any size at post-operative unenhanced computed tomography scan.Patients demographics,SFRs,and CRs were reported and analyzed.Performances of nomograms were evaluated with the area under the curve(AUC).Results:We included 222 patients,the AUCs of GSS,CROES score,and S.T.O.N.E.nephrolithometry score were 0.69(95%confidence interval[CI]0.61-0.78),0.64(95%CI 0.56-0.73),and 0.62(95%CI 0.52-0.71),respectively.Regarding SFRs,at multivariate binomial logistic regression,only the GSS had significance with an odds ratio of 0.53(95%CI 0.31e0.95,p=0.04).We did not find significant correlation with complications,with only a trend for GSS.Conclusion:This is the first study evaluating nomograms in miniaturized PNL.They still show good reliability;however,our data showed lower performances compared to standard PNL.We emphasize the need of further studies to confirm this trend.A dedicated nomogram for minimally invasive PNL may be necessary. | Giorgio Mazzon Francesco Claps Nicola Pavan Simon Choong Guohua Zeng Wenqi Wu Jiehui Zhong Maida Bada Marco Pirozzi Raffaele Vitale Antonio Celia | 2023 | Asian Journal of Urology2023，10，1： | 1 |
| 2 | Arterioureteral fistula:An unusual cause of haematuria 10 years after the implantation of a synthetic iliac-femoral stent显示文摘Dear Editor,The patient had a history of intermittent self-resolving episodes of gross haematuria and was referred to our department for a massive bleeding.At presentation,haemoglobin was 8.6 g/dL and creatinine was 1.37 mg/dL.He was hemodynamically stable,but suffered an important anemization in the subsequent days requiring multiple blood transfusions.In his medical history,it was reported that he had type II diabetes mellitus and the implantation of a right iliac-femoral stent 10 years before. | Luca Ongaro Michele Rizzo Francesco Claps Ottavia Runti Andrea Piasentin Carlo Trombetta Giovanni Liguori | 2023 | Asian Journal of Urology2023，10，4： | 0 |
| 3 | Molecular markers of systemic therapy response in urothelial carcinoma显示文摘Identification of reliable molecular biomarkers that can complement clinical practice represents a fascinating challenge in any cancer field.Urothelial carcinoma is a very heterogeneous disease and responses to systemic therapies,and outcomes after radical cystectomy are difficult to predict.Advances in molecular biology such as next generation sequencing and whole genome or transcriptomic analysis provide promising platforms to achieve a full understanding of the biology behind the disease and can identify emerging predictive biomarkers.Moreover,the ability to categorize patients’risk of recurrence after curative treatment,or even predict benefit from a conventional or targeted therapies,represents a compelling challenge that may reshape both selection for tailored treatment and disease monitoring.Progress has been made but currently no molecular biomarkers are used in the clinical setting to predict response to systemic agents in either neoadjuvant or adjuvant settings highlighting a relevant unmet need.Here,we aim to present the emerging role of molecular biomarkers in predicting response to systemic agents in urothelial carcinoma. | Francesco Claps Maria Carmen Mir Homayoun Zargar | 2021 | Asian Journal of Urology2021，8，4： | 0 |
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