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| 1 | Colorectal cancer in patients under 50 years of age:A retrospective analysis of two institutions' experience显示文摘AIM:To investigate the epidemiological characteristics of colorectal cancer(CRC)in patients under 50 years of age across two institutions.METHODS:Records of patients under age 50 years of age who had CRC surgery over a 16 year period were assessed at two institutions.The following documents where reviewed:admission notes,operative notes,and discharge summaries.The main study variables included:age,presenting symptoms,family history,tumor location,operation,stage/differentiation of disease,and post operative complications.Stage of disease was classified according to the American Joint Committee on Cancer TNM staging system:tumor depth;node status;and metastases.RESULTS:CRC was found in 180 patients under age50 years(87 females,93 males;mean age 41.4±6.2years).Young patients accounted for 11.2%of cases during a 6 year period for which the full data set wasavailable.Eight percent had a 1stdegree and 12%a 2nd degree family CRC history.Almost all patients(94%)were symptomatic at diagnosis;common symptoms included:bleeding(59%),obstruction(9%),and abdominal/rectal pain(35%).Evaluation was often delayed and bleeding frequently attributed to hemorrhoids.Advanced stage CRC(Stage 3 or 4)was noted in 53%of patients.Most tumors were distal to the splenic flexure(77%)and 39%involved the rectum.Most patients(95%)had segmental resections;6 patients had subtotal/total colectomy.Poorly differentiated tumors were noted in 12%and mucinous lesions in 19%of patients of which most had Stage 3 or 4 disease.Twenty-two patients(13%)developed recurrence and/or progression of disease to date.Three patients(ages 42,42and 49 years)went on to develop metachronous primary colon cancers within 3 to 4 years of their initial resection.CONCLUSION:CRC was common in young patients with no family history.Young patients with symptoms merit a timely evaluation to avoid presentation with late stage CRC. | Elizabeth A Myers Daniel L Feingold Kenneth A Forde Tracey Arnell Joon Ho Jang Richard L Whelan | 2013 | World Journal of Gastroenterology2013，19，34： | 9 |
| 2 | Heart Disease and Stroke Statistics—2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee显示文摘 | Donald Lloyd-Jones Robert Adams Mercedes Carnethon Giovanni De Simone T Bruce Ferguson Katherine Flegal Earl Ford Karen Furie Alan Go Kurt Greenlund Nancy Haase Susan Hailpern Michael Ho Virginia Howard Brett Kissela Steven Kittner Daniel Lackland Lynda L | 2009 | Circulation2009，，3： | 4 |
| 3 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 4 | Epithelial–mesenchymal transition in development and cancer显示文摘 | Douglas S Micalizzi Heide L Ford | 2009 | Future Oncol2009，，8： | 2 |
| 5 | Malaria: current status of control, diagnosis, treatment, and a proposed agenda for research and development显示文摘 | Philippe J Guerin Piero Olliaro Francois Nosten Pierre Druilhe Ramanan Laxminarayan Fred Binka Wen L Kilama Nathan Ford Nicholas J White | 2002 | The Lancet Infectious Diseases2002，，9： | 2 |
| 6 | Efficacy and safety of paliperidone extended-release tablets: results of a 6-week, randomized, placebo-controlled study 显示文摘 | Marder SR Kramer M Ford L | 2007 | Biol Psychiatry2007，62，12： | 1 |
| 7 | Maximum flow through a network显示文摘 | FORD L R FULKERSON D R | 1956 | Canadian Journal of Math1956，，8： | 1 |
| 8 | Differential contribution of current and cumulative in dices of lead dose to neuropsychological performance by age 显示文摘 | BLEEXER M L LINDGREN K N FORD D P | 1997 | Neurology1997，48，： | 1 |
| 9 | Cosmic strings and black holes显示文摘 | Aryal M Ford L Vilenkin A | 1986 | Phys Rev1986，34，： | 1 |
| 10 | GRAS Substances显示文摘 | Bernard L Oser R A Ford | 1998 | Food Technology1998，52，9： | 1 |
| 11 | A marked disparity between the expression of prion protein and its message neurones of cns显示文摘 | Ford M J Burton L J Li H | 2002 | Neuroscience2002，111，： | 1 |
| 12 | Data mining in brain imaging 显示文摘 | MEGALOOIKONOMOU V FORD J SHEN L | 2000 | Statistical Methods in Medical Research2000，9，4： | 1 |
| 13 | Genetic improvement in the yield of winter:afurther evaluation 显示文摘 | AUSTIN R B FORD M A MORGAN C L | 1989 | J Agric Sci1989，112，： | 1 |
| 14 | Characteristics of aggregation induced emission in 1,1 -dimethyl-2,3,4,5-tetraphenyl and 1,1,2,3,4,5-hexaphenyl siloles and germoles显示文摘 | MULLIN J L TRACY H J FORD J R | 2007 | J Inorg Organomet Polym Mater2007，17，1： | 1 |
| 15 | Delivery of RNAi mediators显示文摘 | Ford L P Toloue M M | 2010 | Wiley Interdiscip Rev RNA2010，1，： | 1 |
| 16 | Efficacy and safety of paliperidone extended-release tablets:results of a 6-week,randomized,placebo-controlled study显示文摘 | Marder SR Kramer M Ford L | 2007 | Biol Psychiatry2007，65，13： | 1 |
| 17 | Estimation,variation and importance of leaf curvature in Zea mays hybrids显示文摘 | Ford ED Cocke A Horton L Fellner M | 2008 | Agr Forest Meteorol2008，148，： | 1 |
| 18 | Logistic regression a- nalysis of cruise vacation market potential: Demographic and trip attribute perception factors显示文摘 | Vina L D L Ford J | 2001 | Journal of Travel Research2001，39，4： | 1 |
| 19 | Depression is a risk factor for coronary artery disease in men : the precursors study 显示文摘 | FORD D E MEAD L A CHANG P P | 1998 | Arch Intern Med1998，158，： | 1 |
| 20 | Porosity related to structure for low temperature propylene pyrocarbons显示文摘 | L H Ford C F Bilsby | 1976 | J Nucl Mater1976，60，： | 1 |
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