|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | Development, validation and application of a methodology based on solid-phase micro-extraction followed by gas chro- matography coupled to mass spectrometry (SPME/GC-MS) for the determination of pesticide residues in mangoes显示文摘 | MENEZES FILHO A DOS SANTOS F N PEREIRA P A P | 2010 | Talanta2010，81，1： | 1 |
| 3 | Experimental evaluation of fuzzy controllers for the temperature control of the secondary refrigerant in a liquid chiller显示文摘 | Silva F V Filho L C N Silveira V | 2006 | Journal of Food Engineering2006，75，3： | 1 |
| 4 | Mixtures of triblock copolymers E62 P39 E62 and E137 S18 E137:Potential for drug delivery from in situ gelling micellar formulations显示文摘 | Pinho M E N Costa F M L L Filho F B S | | 0，，01： | 1 |
| 5 | Development, validation and application of a methodbased on DI-SPME and GC-MS for determination ofpesticides of different chemical groups in surface andgroundwater samples 显示文摘 | Filho A M Santos F N D De Pereira PAP | 2010 | Microchemical Journal2010，96，1： | 1 |
| 6 | Within-laboratoryvalidation of a multiresidue method for the analysis of 98pesticides in mango by liquid chromatography-tandem mass spectrometry显示文摘 | Filho N F Nasci mento C A Faria E O | 2012 | Food Addi Contam2012，29，4： | 1 |
| 7 | A metropolis algorithm combined with Nelder-Mead simplex applied to nuclear reactor core design 显示文摘 | SACCO W F FILHO H A HENDERSON N | 2008 | Annals of Nuclear Energy2008，35，5： | 1 |
| 8 | Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry (SPME/GC - MS ) for thedetermination of pesticide residues in mangoes显示文摘 | Menezes Filho A dos Santos F N de Paula Pereira P A | 2010 | Talanta2010，81，1： | 1 |
| 9 | 查看详情显示文摘 | Pinto R C F Paschoal C W A Paraguassu W Castro M C Tanaka A A Filho S O B José N M | | 0，，： | 1 |
| 10 | Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry (SPME/GC-MS) for the determination of pesticide residues in mangoes 显示文摘 | Filho A M dos Santos F N Pereira P A | 2010 | Talanta2010，81，12： | 1 |
| 11 | Potts model with q = 3 and 4 states on directed small-world network显示文摘 | da Silva P R O Lima F W S Costa Filho R N | 2013 | Computer Physics Communications2013，184，12： | 1 |
| 12 | E-aluation of residual dentin after con-entional and chemomechanical caries remo-al using SEM显示文摘 | Corra F N Rodrigues Filho L E Rodrigues C R | 2008 | J Clin Pediatr Dent2008，32，2： | 1 |
| 13 | Development, validation and applicationof a method based on DI -SPME and GC - MS for determination of pesticides of different chemical groups in surface and groundwater samples original research Article 显示文摘 | Filho AM Santos F N D Pereira PAD P | 2010 | Microchem J2010，96，1： | 1 |
| 14 | Regional and large-scale pattems in Amazon forest structure and function are mediated by variations in soil physical and chemical properties显示文摘 | Quesada CA Lloyd J Schwarz M Baker TR Phillips OL Pati(n)o S Czimczik C Hodnett MG Herrera R Ameth A Lloyd G Malhi Y Dezzeo N Luizāo F J Santos AJB Schmerler J Arroyo L Silveira M Priante Filho N Jimenez EM Paiva R Vieira I Neill DA Silva N Pe(n)uela MC M | | 0，，： | 1 |
| 15 | Chronic resistance training decreases MuRF - 1 and Atrogin - 1 gene expression but does not modify Akt, GSK - 3 $ \ beta $ and p70S6K levels in rats显示文摘 | Zanchi N E de Siqueira Filho M A R A Lira F S | 2009 | European journal of applied physiology2009，106，3： | 1 |
| 16 | Electrochemical degradation of bisphenol A using a flow reactor with a boron- doped diamond anode显示文摘 | PEREIRA G F ROCHA - FILHO R C BOCCHi N | 2012 | Chemical Engineering Journal2012，，4： | 1 |
| 17 | MorphoSys:an integrated reconfigurable system for data-parallel and computation -intensive applications显示文摘 | Singh H Lee M H Lu G Kurdahi F J Bagherzadeh N Filho E M C | 2000 | IEEE Transaction on Computers2000，49，5： | 1 |
| 18 | Optimization of mass concrete construction using genetic algorithms 显示文摘 | Fairbairn E M Silvoso M M Toledo Filho R D Alves J E L Ebecken N F | 2004 | Computers & structures2004，82，2： | 1 |
| 19 | Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry ( SPME/GC - MS ) for the determination of pesticide residues in mangoes 显示文摘 | FILHO A M DOS S F N PAULA de P P A | 2010 | Talanta2010，81，： | 1 |
| 20 | Ziegler-Natta catalyst for ethylene and propylene polymerization supported on adducts of magnesium chlorides with methyl and ethyl alcohols 显示文摘 | MAGALHAES D N T FILHO O D C COUTINHO F M B | 1991 | European Polymer Journal1991，27，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员