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2篇 您的检索式:作者名="Fengchan Han"
    题名 作者 年代 出处 被引量
1Anti-apoptotic treatment in mouse models of age-related hearing loss显示文摘Age-related hearing loss(AHL),or presbycusis,is the most common neurodegenerative disorder and top communication deficit of the aged population.Genetic predisposition is one of the major factors in the development of AHL.Generally,AHL is associated with an age-dependent loss of sensory hair cells,spiral ganglion neurons and stria vascularis cells in the inner ear.Although the mechanisms leading to genetic hearing loss are not completely understood,caspase-family proteases function as important signals in the inner ear pathology.It is now accepted that mouse models are the best tools to study the mechanism of genetic hearing loss or AHL.Here,we provide a brief review of recent studies on hearing improvement in mouse models of AHL by anti-apoptotic treatment.Fengchan Han Oumei Wang Quanxiang Cai 2016Journal of Otology2016,11,1:4
2Attenuation of hearing loss in DBA/2J mice by anti-apoptotic treatment显示文摘Linlin Yang Heng Zhang Xu Han Xin Zhao Fangyuan Hu Ping Li Gang Xie Lixiang Gao Lin Cheng Xicheng Song Fengchan Han 2015Hearing Research2015,,:1
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