|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Black carbon aerosols and their radiative properties in the Pearl River Delta region显示文摘The climatic and environmental effects of atmospheric aerosols are a hot topic in global science community, and radiative properties of the aerosols are one of the important parameters in assessing climatic change. Here we studied the black carbon concentration and absorption coefficient measured with aethalometers, scattering coefficient measured with nephelometers, and single scattering albedo derived at an atmospheric composition watch station in Guangzhou from 2004 to 2007. Our main results are as follows. The data of black carbon concentration and absorption coefficients measured with instruments cannot be directly used until they are measured in parallel with internationally accepted instruments for comparison, calibration, and reduction. After evaluation of the data, the result shows that the monthly mean of BC concentration varies 3.1―14.8 μg·m-3 and the concentration decreases by about 1 μg·m-3 in average over the four years; It is higher in the dry season with a multi-year mean of 8.9 μg/m3 and lower in the rainy season with a multi-year mean of 8.0 μg·m-3; The extreme maximum of monthly mean concentration occurred in December 2004 and extreme minimum in July 2007, and a 4-year mean is 8.4 μg·m-3. It is also shown that monthly mean scattering coefficient derived varies 129 -565 Mm-1, monthly mean absorption coefficient 32-139 Mm-1, and monthly mean single scattering albedo 0.71-0.91, with annual mean values of 0.80, 0.82, 0.79 and 0.84 for 2004, 2005, 2006 and 2007, respectively. Three instruments were used to take simultaneous measurements of BC in PM10, PM2.5, and PM1 and the results showed that PM2.5 took up about 90% of PM10 and PM1 accounted for about 68% of PM2.5, and BC aerosols are mainly present in fine particulates. The variability of BC concentrations is quite consistent between the Nancun station (141 m above sea level) and the Panyu station (13 m above sea level), which are 8 km apart from each other. The concentration in higher altitude station (Panyu) is consistently lower than the lower altitude station (Nancun), and the difference of annual mean is about 4 μg·m-3. | WU Dui MAO JieTai DENG XueJiao TIE XueXi ZHANG YuanHang ZENG LiMin LI Fei TAN HaoBo BI XueYan HUANG XiaoYing CHEN Jing DENG Tao | 2009 | Science China Earth Sciences2009，52，8： | 58 |
| 2 | A novel strong tracking cubature Kalman filter and its application in maneuvering target tracking显示文摘The fading factor exerts a significant role in the strong tracking idea. However, traditional fading factor introduction method hinders the accuracy and robustness advantages of current strong-tracking-based nonlinear filtering algorithms such as Cubature Kalman Filter(CKF) since traditional fading factor introduction method only considers the first-order Taylor expansion. To this end, a new fading factor idea is suggested and introduced into the strong tracking CKF method.The new fading factor introduction method expanded the number of fading factors from one to two with reselected introduction positions. The relationship between the two fading factors as well as the general calculation method can be derived based on Taylor expansion. Obvious superiority of the newly suggested fading factor introduction method is demonstrated according to different nonlinearity of the measurement function. Equivalent calculation method can also be established while applied to CKF. Theoretical analysis shows that the strong tracking CKF can extract the thirdorder term information from the residual and thus realize second-order accuracy. After optimizing the strong tracking algorithm process, a Fast Strong Tracking CKF(FSTCKF) is finally established. Two simulation examples show that the novel FSTCKF improves the robustness of traditional CKF while minimizing the algorithm time complexity under various conditions. | An ZHANG Shuida BAO Fei GAO Wenhao BI | 2019 | Chinese Journal of Aeronautics2019，32，11： | 22 |
| 3 | Three-dimensional morphometric analysis for hepatectomy of centrally located hepatocellular carcinoma:A pilot study显示文摘AIM: To describe a three-dimensional model(3DM) to accurately reconstruct anatomic relationships of centrally located hepatocellular carcinomas(HCCs).METHODS: From March 2013 to July 2014, reconstructions and visual simulations of centrally located HCCs were performed in 39 patients using a 3D subject-based computed tomography(CT) model with customdeveloped software. CT images were used for the 3D reconstruction of Couinaud's pedicles and hepatic veins, and the calculation of corresponding tumor territories and hepatic segments was performed using Yorktal DMIT software. The respective volume, surgical margin, and simulated virtual resection of tumors were also estimated by this model preoperatively. All patients were treated surgically and the results were retrospectively assessed. Clinical characteristics, imaging data, procedure variables, pathologic features, and postoperative data were recorded and compared to determine the reliability of the model.RESULTS: 3D reconstruction allowed stereoscopic identification of the spatial relationships between physiologic and pathologic structures, and offered quantifiable liver resection proposals based on individualized liver anatomy. The predicted values were consistent with the actual values for tumor mass volume(82.4 ± 109.1 m L vs 84.1 ± 108.9 m L, P = 0.910), surgical margin(10.1 ± 6.2 mm vs 9.1 ± 5.9 mm, P = 0.488), and maximum tumor diameter(4.61 ± 2.16 cm vs 4.53 ± 2.14 cm, P = 0.871). In addition,the number and extent of portal venous ramifications, as well as their relation to hepatic veins, were visualized. Preoperative planning based on simulated resection facilitated complete resection of large tumors located in the confluence of major vessels. And most of the predicted data were correlated with intraoperative findings.CONCLUSION: This 3DM provides quantitative morphometry of tumor masses and a stereo-relationship with adjacent structures, thus providing a promising technique for the management of centrally located HCCs. | Fei Tian Jian-Xiong Wu Wei-Qi Rong Li-Ming Wang Fan Wu Wei-Bo Yu Song-Lin An Fa-Qiang Liu Li Feng Chao Bi Yun-He Liu | 2015 | World Journal of Gastroenterology2015，21，15： | 21 |
| 4 | Electroacupuncture preconditioning protects against focal cerebral ischemia/reperfusion injury via suppression of dynamin-related protein 1显示文摘Electroacupuncture preconditioning at acupoint Baihui(GV20) can reduce focal cerebral ischemia/reperfusion injury. However, the precise protective mechanism remains unknown. Mitochondrial fission mediated by dynamin-related protein 1(Drp1) can trigger neuronal apoptosis following cerebral ischemia/reperfusion injury. Herein, we examined the hypothesis that electroacupuncture pretreatment can regulate Drp1, and thus inhibit mitochondrial fission to provide cerebral protection. Rat models of focal cerebral ischemia/reperfusion injury were established by middle cerebral artery occlusion at 24 hours after 5 consecutive days of preconditioning with electroacupuncture at GV20(depth 2 mm, intensity 1 m A, frequency 2/15 Hz, for 30 minutes, once a day). Neurological function was assessed using the Longa neurological deficit score. Pathological changes in the ischemic penumbra on the injury side were assessed by hematoxylin-eosin staining. Cellular apoptosis in the ischemic penumbra on the injury side was assessed by terminal deoxyribonucleotidyl transferase-mediated d UTP-digoxigenin nick end labeling staining. Mitochondrial ultrastructure in the ischemic penumbra on the injury side was assessed by transmission electron microscopy. Drp1 and cytochrome c expression in the ischemic penumbra on the injury side were assessed by western blot assay. Results showed that electroacupuncture preconditioning decreased expression of total and mitochondrial Drp1, decreased expression of total and cytosolic cytochrome c, maintained mitochondrial morphology and reduced the proportion of apoptotic cells in the ischemic penumbra on the injury side, with associated improvements in neurological function. These data suggest that electroacupuncture preconditioning-induced neuronal protection involves inhibition of the expression and translocation of Drp1. | Gao-feng Zhang Pei Yang Zeng Yin Huai-long Chen Fu-guo Ma Bin Wang Li-xin Sun Yan-lin Bi Fei Shi Ming-shan Wang | 2018 | Neural Regeneration Research2018，13，1： | 16 |
| 5 | Acupuncture preconditioning protects hippocampal neurons from transient ischemia/reperfusion injury显示文摘The present study established a model of brain ischemia in aged rats using four-vessel occlusion.We observed hippocampal CA1 neuronal apoptosis and apoptosis-mediated protease caspase-3 expression following preconditioning of electroacupuncture at Baihui(GV 20).Our results showed that the number of hippocampal CA1 normal neurons was decreased,and degenerated neurons were increased 12 hours to 3 days following cerebral ischemia/reperfusion.The number of hippocampal CA1 apoptotic neurons and caspase-3-positive neurons in rats with cerebral ischemia/reperfusion injury was significantly decreased following acupuncture preconditioning.Acupuncture preconditioning protects aged rats against ischemia/reperfusion injury by regulating caspase-3 protein expression. | Mingshan Wang Haipeng Zhou Fei Shi Shilong Ma Yanlin Bi Yuqiu Liu Hong Liu Haiou Li | 2011 | Neural Regeneration Research2011，6，15： | 12 |
| 6 | Effect of atmospheric aerosol on surface ozone variation over the Pearl River Delta region显示文摘Our analysis of the surface aerosol and ultraviolet(UV) measurements in Pearl River Delta(PRD) region shows that the sur-face UV radiation is reduced by more than 50% due to high aerosol concentrations.This has important impacts on urban eco-system and photochemistry,especially on ozone photochemical production over the region.The quantitative effect of aerosols on surface ozone is evaluated by analyzing surface observations(including ozone,ultraviolet radiation,aerosol radiative pa-rameters) and by using radiative and chemical models.A case study shows that the aerosol concentrations and UV radiation are significantly correlated with ozone concentrations.The correlation coefficient between the aerosol optical depth(AOD) and the PM10 mass concentration is very high,with a maximum of 0.98,and the AOD and UV radiation/ozone is anti-correlated,with a correlation coefficient of -0.90.The analysis suggests that ozone productivity is significantly decreased due to the reduction of UV radiation.The noon-time ozone maximum is considerably depressed when AOD is 0.6,and is further decreased when AOD is up to 1.2 due to the reduction of ozone photochemical productivity.Because the occurring probability of aerosol optical depth for AOD550 nm≥0.6 and AOD340 nm≥1.0 is 47,and 55% respectively during the dry season(October,November,December,January),this heavy aerosol condition explains the low ozone maximum that often occurs in the dry season over the Guangzhou region.The analysis also suggests that the value of single scattering albedo(SSA) is very sensitive to the aerosol radiative effect when the radiative and chemical models are applied,implying that the value of SSA needs to be carefully studied when the models are used in calculating ozone production. | DENG XueJiao ZHOU XiuJi WU Dui TIE XueXi TAN HaoBo LI Fei BI XueYan DENG Tao JIANG DeHai | 2011 | Science China Earth Sciences2011，54，5： | 10 |
| 7 | Clinical Application of Loewenstein Occupational Therapy Cognitive Assessment Battery-Second Edition in Evaluating of Cognitive Function of Chinese Patients with Post-stroke Aphasia显示文摘Objective To investigate the clinical application value of Loewenstein Occupational Therapy Cognitive Assessment(LOTCA)battery in Chinese patients with post-stroke aphasia.Methods Cognitive functions of 59 Chinese patients with aphasia following a stroke were assessed with the Chinese version of the second edition of LOTCA battery and their linguistic functions were tested with the Western Aphasia Battery(WAB)Scale,respectively.The results of LOTCA were analyzed and compared across different groups,in the light of gender,age,educational background,the length of illness,and the degree of aphasia.Results Neither the score of subtests of the LOTCA nor the overall scores of LOTCA of aphasia patients with different gender and educational background differed(all P>0.05).In different age groups,apart from thinking operation(F=3.373,P=0.016),visuomotor organization(F=3.124,P=0.022),attention(F=3.729,P=0.009)and the total score(F=2.683,P=0.041),there was no difference in terms of the other subtest scores of LOTCA(all P>0.05).In the groups of different length of time with illness,apart from orientation(F=2.982,P=0.039)and attention(F=3.485,P=0.022),the score of other subtests and the total score of LOTCA were not different(all P>0.05).In the groups of different degree of aphasia,apart from attention(F=2.061,P=0.074),both the score of other subtests and the total score of LOTCA differed(all P<0.05).Conclusion LOTCA might be suitable to assessing the cognitive ability of post-stroke Chinese patients with aphasia. | Zeng-zhi Yu Shu-jun Jiang Jun Li Sheng Bi Fei Li Tao Xie Rui Wang Xiao-tan Zhang | 2013 | Chinese Medical Sciences Journal2013，28，3： | 9 |
| 8 | Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese显示文摘Objective To study the relationship between resting heart rate and blood lipid level.Methods A total of 9 415 subjects aged≥40 years were included in the present study.Their resting heart rate was monitored and their serum levels of triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C)and high density lipoprotein cholesterol(HDL-C)were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults.Results The subjects were divided into group A with their resting heart rate<70 beats/min,group B with their resting heart rate=70-79 beats/min,group C with their resting heart rate=80-89 beats/min,and group D with their resting heart rate≥90 beats/min.High TG,TC,and LDL-C were presented across the resting heart rate(Ptrend<0.01).Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate≥90 beats/min than in those with their resting heart rate<70 beats/min(OR=1.42;95%CI:1.16-1.74 and OR=1.33;95%CI:1.09-1.64,respectively).Conclusion Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects. | SUN Ji Chao HUANG Xiao Lin DENG Xin Ru LV Xiao Fei LU Jie Li CHEN Yu Hong BI Yu Fang WANG Wei Qing XU Min NING Guang | 2014 | Biomedical and Environmental Sciences2014，27，8： | 5 |
| 9 | 隐甲藻和裂殖壶藻醇水提物不同极性萃取物的抗氧化活性研究(英文)显示文摘目的:评价隐甲藻和裂殖壶藻醇水提物的石油醚萃取相、乙酸乙酯萃取相、正丁醇萃取相和水相的抗氧化活性水平,为综合利用两种微藻提供理论依据。创新点:隐甲藻和裂殖壶藻是二十二碳六烯酸(DHA)的重要原料,然而提取DHA后剩余的藻渣未得到充分利用。本文首次对两种微藻的极性提取物的不同极性部位进行抗氧化活性评价,并初步确定多酚类化合物是其发挥抗氧化作用的主要物质成分,为综合利用两种微藻提供了理论依据和参考。方法:用70%乙醇浸提隐甲藻和裂殖壶藻藻粉,所得粗提物分别使用石油醚、乙酸乙酯、正丁醇和水依次萃取,得到不同极性组分萃取物。采用总抗氧化能力、2,2-二苯基-1-三硝基苯肼(DPPH)自由基清除能力、亚铁离子螯合能力及总还原力等方法对不同极性组分的萃取物进行抗氧化活性评价。采用Folin-Ciocalteu方法测定样品中总多酚含量,采用分光光度法测定样品中总黄酮含量。结论:本实验结果显示,隐甲藻和裂殖壶藻醇水提物的不同极性组分具有较好的抗氧化作用(图2~5)。相关性分析结果表明萃取物中的多酚类化合物与其抗氧化水平显著相关(表2和表3),因此,我们推测多酚类化合物是两种微藻的主要抗氧化成分。综上所述,隐甲藻和裂殖壶藻具有综合开发利用潜力,可深入研究。 | Jin-hui YU Yu WANG Jie SUN Fei BIAN Gao CHEN Yan ZHANG Yu-ping BI Ying-jie WU | 2017 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2017，18，9： | 4 |
| 10 | Cost-benefit analysis of China’s Action Plan for Air Pollution Prevention and Control显示文摘China’s rapid economic growth has caused severe air pollution and public health problems.Therefore,the Chinese government launched the Action Plan for Air Pollution Prevention and Control(hereinafter referred to as the“Air Plan”)in 2013-2017 to improve air quality and safeguard public health.In this study,an analytical framework for a cost-benefit analysis applicable to China was constructed,and the costs and benefits of the implementation of the“Air Plan”in 30 cities and provinces in China from 2013 to 2017 were evaluated.Results show that the total cost of implementation of the“Air Plan”is 1.6511 trillion RMB.The benefits of air quality improvement were determined to be 2.4691 trillion RMB through the willingness-to-pay method to calculate the economic loss of premature deaths.The net benefit related to the implementation of the“Air Plan”was 818 billion RMB.The public health benefit of air quality improvement was 1.5 times the cost of the nationwide implementation of the“Air Plan”.At the provincial level,net benefits that reach 279.3 billion RMB were the highest in Guangdong,whereas the benefit-cost ratio,where the benefit was 5.5 times the cost,was the highest in Fujian.Estimations in this study can serve as a reference for China in formulating similar environmental policies and implementing the “3-year Plan to Defend the Blue Sky”.In addition,these estimations have practical significance for advancing the long-term effective mechanisms of the cost-benefit analysis of China5s environmental policies. | Jing ZHANG Hongqiang JIANG Wei ZHANG Guoxia MA Yanchao WANG Yaling LU Xi HU Jia ZHOU Fei PENG Jun BI Jinnan WANG | 2019 | Frontiers of Engineering Management2019，6，4： | 4 |
| 11 | Significance of MD-2 and MD-2B expression in rat liver during acute cholangitis显示文摘AIM: To investigate the expression of myeloid differentiation protein-2 (MD-2), MD-2B (a splicing isoform of MD-2 that can block Toll-like receptor 4 (TLR4)/MD-2 LPS-mediated signal transduction) and TLR4 in the liver of acute cholangitis rats. METHODS: Male Sprague-Dawley rats (SPF level) were randomly divided into four groups: (A) sham-operated group; (B) simple common bile duct ligation group; (C)acute cholangitis group; and (D) acute cholangitis anti- TLR4 intervention group (n = 25 per group). Rat liver tissue samples were used to detect TLR4, MD-2 and MD-2B mRNA expression by fluorescence quantitative PCR in parallel with pathological changes. RESULTS: In acute cholangitis, liver TLR4 and MD-2 mRNA expression levels at 6, 12, 24, 48 and 72 h were gradually up-regulated but MD-2B mRNA expression gradually down-regulated (P < 0.05). After TLR4 antibody treatment, TLR4 and MD-2 mRNA expression were lower compared with the acute cholangitis group (P < 0.05). However, MD-2B mRNA expression was higher than in the acute cholangitis group (P < 0.05). MD-2 and TLR4 mRNA expressions were positively correlated (r = 0.94981, P < 0.05) and MD-2B mRNA expression was negatively correlated with MD-2 and TLR4 mRNA (r = -0.89031, -0.88997, P< 0.05). CONCLUSION: In acute cholangitis, MD-2 plays an important role in the process of TLR4- mediated in? am- matory response to liver injury while MD-2B plays a negative regulatory role. | Hui-Lai Miao, Zhi-Dong Qiu, Fu-Long Hao, Yong-Hui Bi, Ming-Yi Li, Ming Chen, Nian-Ping Chen, Fei Zhou, Department of Hepatobiliary Surgery, the Affiliated Hospital of Guangdong Medical College, Zhanjing 524001, Guangdong Province, China Hepatobiliary Surgery, Research Institute of Guangdong Medical College, Zhanjiang 524001, Guangdong Province, China | 2010 | World Journal of Hepatology2010，2，6： | 3 |
| 12 | Anti-rheumatoid arthritic effect of volatile components in notopterygium incisum in rats via anti-inflammatory and anti-angiogenic activities显示文摘Notopterygium incisum(QH) has been used for the treatment of rheumatoid arthritis(RA), and volatile oils may be its mainly bioactive constituents. The present study was designed to analyze the volatile compounds in QH and to determine the anti-arthritic capacity of Notopterygium volatile oils and the potential mechanism of action. The volatile compounds analysis was conducted by GC-MS. The anti-arthritic capacity test of the volatile oils was conducted on adjuvant-induced arthritis(AIA) rats. The anti-inflammatory property was tested in NO release model in RAW 264.7 cells. Endothelial cells were used to evaluate the anti-proliferative and anti-tube formative effects. 70 compounds were analyzed by GC-MS in the volatile oils. Notopterygium volatile oils weakened the rat AIA in a dose-dependent manner(2, 4, and 8 g crude drug/kg). The NO production by RAW 264.7 was decreased by more than 50% in Notopterygium volatile oils(5, 15, and 45 μg·mL^(-1)) pretreated groups. Notopterygium volatile oils also inhibited EAhy926 cell proliferation and further delayed EAhy926 cell capillary tube formation in a concentration-dependent manner. The anti-NO productive, anti-proliferative, and anti-tube formative effects of Notopterygium volatile oils strongly suggested that the therapeutic effect of QH in AIA might be related to the potent anti-inflammatory and anti-angiogenic capacities of the volatile oils. | BI Jian-Ping LI PING XU Xi-Xi WANG Ting LI Fei | 2018 | Chinese Journal of Natural Medicines2018，16，12： | 3 |
| 13 | Dog-transmitted Rabies in Beijing, China显示文摘Rabies remains a continuous threat to public health in Beijing.In this study,a total of 224 brain tissues were collected from suspected infected stray dogs within Beijing between January 2015 and December 2016.Among them,total of 67 samples were diagnosed positive for rabies.In the phylogenetic analysis,rabies in Beijing is currently a relatively independent public health issue originating from local rabid dogs apart from the imported cases from elsewhere in the country.Because vaccination of unregistered dogs against rabies is still neglected in Beijing and other regions of China,national and local authorities should play central roles in all related aspects,such as development of policies,engagement of stakeholders for public and professional education,entire vaccination process,and animal management. | ZHANG Jing Yuan ZHANG Bi ZHANG Shou Feng ZHANG Fei LI Nan LIU Ye HU Rong Liang | 2017 | Biomedical and Environmental Sciences2017，30，7： | 3 |
| 14 | Safety,tolerability,and pharmacokinetics of BAT8001 in patients with HER2-positive breast cancer:An open-label,dose-escalation,phase I study显示文摘Background:The introductions of anti-human epidermal growth factor receptor-2(HER2)agents have significantly improved the treatment outcome of patients with HER2-positive breast cancer.BAT8001 is a novel antibodydrug conjugate targeting human epidermal growth factor receptor-2(HER2)-expressing cells composed of a trastuzumab biosimilar linked to the drug-linker Batansine.This dose-escalation,phase I study was designed to assess the safety,tolerability,pharmacokinetics,and preliminary anti-tumor activity of BAT8001 in patients with HER2-positive locally advanced or metastatic breast cancer.Methods:This trial was conducted in subjects with histologically confirmed HER2-positive breast cancer(having evaluable lesions and an Eastern Cooperative Oncology Group performance status of 0 or 1)using a 3+3 design of escalating BAT8001 doses.Patients received BAT8001 intravenously in a 21-day cycle,with dose escalation in 5 cohorts:1.2,2.4,3.6,4.8,and 6.0 mg/kg.The primary objective was to evaluate the safety and tolerability of BAT8001.Preliminary activity of BAT8001 was also assessed as a secondary objective.Results:Between March 2017 to May 2018,29 HER2-positive breast cancer patients were enrolled.The observed dose-limiting toxicities were grade 4 thrombocytopenia and grade 3 elevated transaminase.The maximum tolerated dose was determined to be 3.6 mg/kg.Grade 3 or greater adverse events(AEs)occurred in 14(48.3%)of 29 patients,including thrombocytopenia in 12(41.4%)patients,aspartate aminotransferase increased in 4(13.8%)patients,γ-glutamyl transferase increased in 2(6.9%)patients,alanine aminotransferase increased in 2(6.9%)patients,diarrhea in 2(6.9%)patients.Objective response was observed in 12(41.4%,95%confidence interval[CI]=23.5%-61.1%)and disease control(including patients achieving objective response and stable disease)was observed in 24(82.8%,95%CI=64.2%-94.2%)patients.Conclusions:BAT8001 demonstrated favorable safety profiles,with promising anti-tumor activity in patients with HER2-positive locally advanced or metastatic breast cancer.BAT8001 has the potential to provide a new therapeutic option in patients with metastatic HER2-positive breast cancer. | Ruoxi Hong Wen Xia Liye Wang Kaping Lee Qianyi Lu Kuikui Jiang Shengfeng Li Jinquan Yu Jin Wei Weijia Tang Danyang Zhou Xin An Jiajia Huang Cong Xue Xiwen Bi Yanxia Shi Zhongyu Yuan Fei Xu Shusen Wang | 2021 | Cancer Communications2021，41，2： | 2 |
| 15 | Optimal design of nanofiltration system for surface water treatment显示文摘Both reverse osmosis(RO) and nanofiltration(NF) membranes have been increasingly used for water purification and desalination. However, the salt rejection of NF membranes is quite different from that of RO membranes,which makes a significant distinction in their process designs. This work started from the performance investigation of a single NF membrane element and then focused on the process design of the NF system for surface water treatment. In experimental tests, it was found that the observed rejection of the NF element becomes nearly constant when the concentrate flow is large enough, while the membrane flux of the NF element is quite stable regardless of the water flow across the membrane surface. These findings can be used to instruct the process design of the NF system for surface water treatment. In process design, a two-stage arrangement is sufficient for the NF system to reach the highest water recovery, while the RO system requires a three-stage arrangement. | Fei Bi Haiyang Zhao Zhijun Zhou Lin Zhang Huanlin Chen Congjie Gao | 2016 | Chinese Journal of Chemical Engineering2016，24，12： | 2 |
| 16 | Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese显示文摘Objective To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.Methods The relation between serum calcium level and elevated BaPWV was studied in 9 615subjects.The mean value of left and right BaPWV was analyzed.BaPWV was defined as high when it was?1 752.5 cm/s(the upper quartile)either side.Results The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level(P<0.05).The prevalence of elevated BaPWV was significantly higher in subjects of the second,third and highest quartiles than in those of the lowest quartile(26.9%,28.4%,and 33.2%vs23.7%,P=0.0116,P=0.0004,and P<0.0001).Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32-fold higher in subjects of the highest quartile than in those of the lowest quartile(OR=1.32,95%CI:1.08-1.60).Conclusion The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness,independent of conventional risk factors,in middle-aged and elderly Chinese subjects. | DENG Xin Ru ZHANG Yin Fei WANG Tian Ge XU Bai Hui SUN Ji Chao ZHAO Lie Bin XU Min CHEN Yu Hong WANG Wei Qing BI Yu Fang LU Jie Li | 2014 | Biomedical and Environmental Sciences2014，27，8： | 2 |
| 17 | Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the China Cardiometabolic Disease and Cancer Cohort(4C)Study显示文摘Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.Methods The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid assessment.The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models.Results A total of 30,941 men and 62,361 women were eligible for the current analysis.Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and women.The thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women. | ZHU Yuan Yue ZHENG Rui Zhi WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui Jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min WU Sheng Li YANG Tao DENG Hua Cong ZHAO Jia Jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang | 2021 | Biomedical and Environmental Sciences2021，34，1： | 2 |
| 18 | Comparative transcriptomics analysis of Zygosaccharomyces mellis under high-glucose stress显示文摘The high-glucose tolerance of yeast is the main factor determining the efficiency of high-density alcohol fermentation.Zygosaccharomyces mellis LGL-1 isolated from honey could survive under 700 g/L high-glucose stress and its tolerant characteristics were identified in our previous study.This study was performed to explore and clarify the high-glucose tolerance mechanism of Z.mellis LGL-1.Comparative transcriptomic analysis was used to analyze the genes with differential expression in Z.mellis under high-glucose conditions of 300,500 and 700 g/L.With 300 g/L samples as reference,there were 937 and 2380 differentially expressed genes(DEGs)in the 500 and 700 g/L samples,respectively.Meanwhile,there was 825 significant DEGs in the 700 g/L samples compared with that of the 500 g/L samples.The result revealed that transcriptional changes in multiple metabolic pathways occur in response to high-glucose stress.q-RT PCR analysis further confirmed that several stress response pathways,such as the high osmolarity glycerol mitogen-activated protein kinase(HOG-MAPK)signal transduction pathway,trehalose synthesis pathway and oxidative stress response are closely related to high-glucose tolerance in Z.mellis.This study clarifies mechanisms of Z.mellis in response to high-glucose osmotic stress,providing theoretical basis for the process control of high-density alcohol fermentation. | Gongliang Liu Xinyu Bi Changli Tao Yongtao Fei Sujuan Gao Jinglong Liang Weidong Bai | 2021 | Food Science and Human Wellness2021，10，1： | 2 |
| 19 | Study of the intrinsic mechanisms of nickel additive for grain refinement and strength enhancement of laser aided additively manufactured Ti–6Al–4V显示文摘It is well-known that grain refiners can tailor the microstructure and enhance the mechanical properties of titanium alloys fabricated by additive manufacturing(AM). However, the intrinsic mechanisms of Ni addition on AM-built Ti–6Al–4V alloy is not well established. This limits its industrial applications. This work systematically investigated the influence of Ni additive on Ti–6Al–4V alloy fabricated by laser aided additive manufacturing(LAAM). The results showed that Ni addition yields three key effects on the microstructural evolution of LAAM-built Ti–6Al–4V alloy.(a) Ni additive remarkably refines the prior-β grains, which is due to the widened solidification range. As the Ni addition increased from 0 to 2.5 wt. %, the major-axis length and aspect ratio of the prior-β grains reduced from over 1500 μm and 7 to 97.7 μm and1.46, respectively.(b) Ni additive can discernibly induce the formation of globular α phase,which is attributed to the enhanced concentration gradient between the β and α phases. This is the driving force of globularization according to the termination mass transfer theory. The aspect ratio of the α laths decreased from 4.14 to 2.79 as the Ni addition increased from 0 to2.5 wt. %.(c) Ni as a well-known β-stabilizer and it can remarkably increase the volume fraction of β phase. Room-temperature tensile results demonstrated an increase in mechanical strength and an almost linearly decreasing elongation with increasing Ni addition. A modified mathematical model was used to quantitatively analyze the strengthening mechanism. It was evident from the results that the α lath phase and the solid solutes contribute the most to the overall yield strength of the LAAM-built Ti–6Al–4V–x Ni alloys in this work. Furthermore, the decrease in elongation with increasing Ni addition is due to the deterioration in deformability of the β phase caused by a large amount of solid-solution Ni atoms. These findings can accelerate the development of additively manufactured titanium alloys. | Shang Sui Youxiang Chew Fei Weng Chaolin Tan Zhenglin Du Guijun Bi | 2022 | International Journal of Extreme Manufacturing2022，4，3： | 1 |
| 20 | Prediction of adolescent subjective well being: A machine learning approach显示文摘Background Subjective well-being(SWB),also known as happiness,plays an important role in evaluating both mental and physical health.Adolescents deserve specific attention because they are under a great variety of stresses and are at risk for mental disorders during adulthood.Aim The present paper aims to predict undergraduate students1 SWB by machine learning method.Methods Gradient Boosting Classifier which was an innovative yet validated machine learning approach was used to analyse data from 10518 Chinese adolescents.The online survey included 298 factors such as depression and personality.Quality control procedure was used to minimise biases due to online survey reports.We applied feature selection to achieve the balance between optimal prediction and result interpretation.Results The top 20 happiness risks and protective factors were finally brought into the predicting model.Approximately 90%individuals'SWB can be predicted correctly,and the sensitivity and specificity were about 92%and 90%,respectively.Conclusions This result identifies at-risk individuals according to new characteristics and established the foundation for adolescent prevention strategies. | Naixin Zhang Chuanxin Liu Zhixuan Chen Lin An Decheng Ren Fan Yuan Ruixue Yuan Lei Ji Yan Bi Zhenming Guo Gaini Ma Fei Xu Fengping Yang Liping Zhu Gabirel Robert Yifeng Xu Lin He Bo Bai Tao Yu Guang He | 2019 | General Psychiatry2019，32，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员