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1Liver transplantation for patients with hepatocellular carcinoma at the Liver Cancer Institute of Fudan University, China显示文摘Background Selection of patients with hepatocellular carcinoma (HCC) for orthotopic liver transplantation (OLT) remains controversial. Since there is a trend to expand the transplant criteria for HCC patients, we reviewed the data of patients with HCC who had received OLT at our institute to determine their survival and prognostic factors.Methods A total of 67 patients with HCC who had undergone OLT from April 2001 through December 2003 were reviewed retrospectively. Selection OLT candidates with HCC was dependent on the anatomical characteristics and/or the severity of underlying liver cirrhosis. The 67 patients were followed up for more than 6 months after transplantation. Their survival rate was calculated by the Kaplan-Meier method. Univariate and multivariate analyses using the Cox proportional hazards regression model were performed to reveal the factors affecting the survival rate.Results No perioperative death occurred in this series. The 1- and 2-year cumulative survival rates were 90.0% and 65.6%, and the disease-free survival (DFS) rates were 77.5% and 62.5% respectively. Univariate analysis revealed the tumor size, portal vein tumor thrombus (PVTT), serum alpha-fetoprotein level, bilobular distribution of tumors, pTNM stage and histological differentiation were statistically significant factors affecting the DFS ( P <0.05). Multivariate analysis showed tumor size and PVTT were independent and statistically significant factors affecting the DFS ( P =0.005 and 0.010, respectively). In this series, all but 2 received systemic chemotherapy, among them 13 had tumor recurrence within 8 months after OLT. Conclusions OLT is indicated for patients with HCC, even for some patients with end-stage liver disease who may survive longer without tumor recurrence. Adjuvant chemotherapy may decrease the recurrence of HCC after OLT.ZHOUJian FANJia WUZhi-quan QIUShuang-jian HUANGXiao-wu YUYao WANGZheng SUNJian XIAOYong-sheng HEYi-feng YANGGuo-huan SONGKang YUANZhou WANGYu-qi TANGZhao-you 2005Chinese Medical Journal2005,,8:26
2Evidence for sea‐level falls in the Permian‐Triassic transition in the Ziyun area, South China显示文摘WuYa‐Sheng JiangHong‐Xia FanJia‐Song 2010Geol J (鈥?)2010,,2:1
3A case study of EM38 for characterizing topsoil thickness in a reclaimed field显示文摘Yurui Sun Caixia Cai Jianhui Lin Qiang Cheng Fanjia Meng Daoliang Li 2011Journal of the Chinese Institute of Engineers2011,,6:1
4All‑Fiber Integrated Thermoelectrically Powered Physiological Monitoring Biosensor显示文摘Advanced fabric electronics for long-term personal physiological monitoring,with a self-sufficient energy source,high integrity,sensitivity,wearing comfort,and homogeneous components are urgently desired.Instead of assembling a self-powered biosensor,comprising a variety of materials with different levels of hardness,and supplementing with a booster or energy storage device,herein,an all-fiber integrated thermoelectrically powered physiological monitoring device(FPMD),is proposed and evaluated for production at an industrial scale.For the first time,an organic electrochemical transistor(OECT)biosensor is enabled by thermoelectric fabrics(TEFs)adaptively,sustainably and steadily without any additional accessories.Moreover,both the OECT and TEFs are constructed using a cotton/poly(3,4-ethylenedioxythiophene):poly(styrenesulfon ate)/dimethylsulfoxide/(3-glycidyloxypropyl)trimethoxysilane(PDG)yarn,which is lightweight,robust(90°bending for 1000 cycles)and sweat-resistant(ΔR/R0=1.9%).A small temperature gradient(ΔT=2.2 K)between the environment and the human body can drive the high-gain OECT(71.08 mS)with high fidelity,and a good signal to noise ratio.For practical applications,the on-body FPMD produced an enduring and steady output signal and demonstrated a linear monitoring region(sensitivity of 30.4 NCR(normalized current response)/dec,10 nM~50µM)for glucose in artificial sweat with reliable performance regarding anti-interference and reproducibility.This device can be expanded to the monitoring of various bio-markers and provides a new strategy for constructing wearable,comfortable,highly integrated and self-powered biosensors.Xing Qing Huijun Chen Fanjia Zeng Kangyu Jia Qing Shu Jianmei Wu Huimin Xu Weiwei Lei Dan Liu Xungai Wang Mufang Li Dong Wang 2023Advanced Fiber Materials2023,5,3:1
5HYDRUS-2D simulations of water movement in a drip irrigation system under soilless substrate显示文摘A comprehensive understanding of the distribution and water movement of the substrate in root areas is crucial to the design and management of drip irrigation systems,which is a significant step to maximizing crop water use efficiency by understanding the hydrodynamics in soilless substrates.In this study,an improved HYDRUS-2D model by the dynamic root growth model was used to simulate water movement under the condition of drip irrigation and the water uptake process of the root,and then,compared with the observed data.Substrate water content under drip irrigation was also measured with the calibrated ECH20-EC5 sensors.The situation of substrate water movement was analyzed under the conditions of different depths,different initial water content,and different irrigation amount.The substrate water movement under different drip irrigation conditions was explored.The results showed that incorporating the defined initial and boundary conditions and the hydraulic characteristics of the substrate into the model enabled HYDRUS model to predict the movement and position of water in unsaturated porous media by solving Richards equation.Under drip irrigation,the substrate wetting body was approximately a quarter ellipse,and the water would continue to move to the area where the wetting front did not reach within 1 h after irrigation.The simulation results of the improved HYDRUS-2D model agreed well with those observed by the ECH2O-EC5 sensors,and the model could provide a basis for precision irrigation of soilless substrate culture under drip irrigation.Lei Geng Li Li Wei Li Chengfei Yang Fanjia Meng 2022International Journal of Agricultural and Biological Engineering2022,15,3:0
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