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| 1 | Defining the Functional Network of Epigenetic Regulators in Arabidopsis thaliana显示文摘薄片薄片和 ChIP-seq 技术的开发允许为 epigenetic 管理者的联系染色质的标记和有约束力的地点的染色体宽的高分辨率的介绍。然而,发信号因为指导 epigenetic 修饰词到他们的目标地点没被理解。在这份报纸,我们测试了那个染色体地点能影响的假设用染色质制图的 epigenetic 管理者(CC ) 的参与排队,它把相同 transgene 构造在 Arabidopsis 染色体在不同地点插入了。为酶记者基因的 epigenetic silencing 显示出证据的四根 CC 线与个别地指向 epigenetic 管理者 LHP1, MOM1, CMT3, DRD1, DRM2, SUVH2, CLF,和 HD1 的 RNAi 向量被转变。在 silencing 的一个特别 epigenetic 管理者的参与在一根 CC 线的 transgene 地点被重要改变在管理者的表示的抑制以后在酶表示决定。我们的结果建议指向 epigenetic 管理者能被染色体地点以及顺序上下文影响。另外,一个 epigenetic 管理者的相对重要性能被织物身份影响。我们也报导一条新奇途径通过在通常认为的下游的目标的基因表示用改变聚类管理者的分析预言在 epigenetic 管理者之间的相互作用,包括内长的 loci 和 transgenes,在 epigenetic 异种或 RNAi 线。我们的数据支持服务在更高的植物协调并且控制全球基因表示的 epigenetic 管理者的一个复杂、动态的网络的存在。 | Chongyuan Luo Brittany G. Durgin Naohide Watanabe Eric Lain | 2009 | Molecular Plant2009，2，4： | 2 |
| 2 | RNAi-mediated pinoresinol lariciresinol reductase gene silencing in flax ( Linum usitatissimum L.) seed coat: Consequences on lignans and neolignans accumulation显示文摘 | Sullivan Renouard Marie-Aude Tribalatc Frederic Lamblin Ga?lle Mongelard Ophélie Fliniaux Cyrielle Corbin Djurdjica Marosevic Serge Pilard Hervé Demailly Laurent Gutierrez Christophe Hano Fran?ois Mesnard Eric Lainé | 2014 | Journal of Plant Physiology2014，，15： | 1 |
| 3 | Recovery of plants from cryopreserved embryogenic cell suspensions of Pinus caribaea显示文摘 | Eric Laine Pascale Bade Alain David | 1992 | Plant Cell Reports (-)1992，，5： | 1 |
| 4 | Nutrient Modification of the Innate Immune Response: A Novel Mechanism by Which Saturated Fatty Acids Greatly Amplify Monocyte Inflammation显示文摘 | Eric A. Schwartz Wei-Yang Zhang Sheetal K. Karnik Sabine Borwege Vijay R. Anand Phyllis S. Laine Yali Su Peter D. Reaven | 2010 | Arteriosclerosis Thrombosis and Vascular Biology2010，，4： | 1 |
| 5 | EMMPRIN/CD147 and MMP modulator in cancer development and tissue repair 显示文摘 | Eric E G Thanh H X A lain M | 2005 | Bioehin Ie2005，87，9： | 1 |
| 6 | The use of the phosphomannose isomerase gene as alternative selectable marker for Agrobacterium-mediated transformation of flax (Linum usitatissimum)显示文摘 | Frédéric Lamblin Aurélie Aimé Christophe Hano Isabelle Roussy Jean-Marc Domon Bart Droogenbroeck Eric Lainé | 2007 | Plant Cell Reports2007，，6： | 1 |
| 7 | Nonlinear isotropic constitutive laws: choice of the three invariants, convex potentials and constitutive inequalities 显示文摘 | Eric Laine Claude Vallee Danielle Fortune | 1999 | International Journal of Engineering Science1999，37，： | 1 |
| 8 | Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors显示文摘Background and purpose Depression is common after stroke and is often treated with antidepressant medications(AD).ADs have also been hypothesised to improve stroke recovery,although recent randomised trials were neutral.We investigated the patterns of in-hospital AD initiation after ischaemic stroke and association with clinical and readmission outcomes.Methods All Medicare fee-for-service beneficiaries aged 65 or older hospitalised for ischaemic stroke in participating Get With The Guidelines-Stroke hospitals between April and December 2014 were eligible for this analysis.Outcome measures included days alive and not in a healthcare institution(home time),all-cause mortality and readmission within 1-year postdischarge.Propensity score(PS)-adjusted logistic regression models were used to evaluate the associations between AD use and each outcome measure.We also compared outcomes in patients prescribed selective serotonin reuptake inhibitors(SSRIs)AD versus those prescribed non-SSRI ADs.Results Of 21805 AD naive patients included in this analysis,1835(8.4%)were started on an AD at discharge.Patients started on an AD had higher rates of depression and prior ischaemic stroke,presented with higher admission National Institutes of Health Stroke Scale score and were less likely to be discharged home.Similarly,patients started on an SSRI had lower rates of discharge to home.Adjusting for stroke severity,patients started on an AD had worse all-cause mortality,all-cause readmission,major adverse cardiac events,readmission for depression and decreased home-time.However,AD use was also associated with an increased risk for the sepsis,a falsification endpoint,suggesting the presence of residual confounding.Conclusions Patients with ischaemic stroke initiated on AD therapy are at increased risk of poor clinical outcomes and readmission even after PS adjustment,suggesting that poststroke depression requiring medication is a poor prognostic sign.Further research is needed to explore the reasons why depression is associated with worse outcome,and whether AD treatment modifies this risk or not. | Mark R Etherton Shreyansh Shah Xu Haolin Ying Xian Lesley Maisch Deidre Hannah Brianna Lindholm Barbara Lytle Laine Thomas Eric E Smith Gregg C Fonarow Lee H Schwamm Deepak L Bhatt Adrian F Hernandez Emily C O'Brien | 2021 | Stroke & Vascular Neurology2021，6，3： | 0 |
| 9 | C4NP-无铅倒装晶片焊凸形成生产工艺与可靠性数据(英文)显示文摘受控倒塌芯片连接新工艺是一种由IBM公司开发、由Suss Micro Tec公司推向商品化的新型焊凸形成技术。受控倒塌芯片连接新工艺采用各种无铅焊料合金致力于解决现有的凸台。形成技术限定,使低成本小节距焊凸形成成为可能。受控倒塌芯片连接新工艺是一种焊球转移技术,熔焊料被注入预先制成并可重复使用的玻璃模板(模具)。这种注满焊料的模具在焊料转入圆片之前先经过检查以确保高成品率。注满焊料的模具与圆片达到精确的接近后以与液态熔剂复杂性无关的简单工序转移在整个300mm(或300mm以下)圆片上。受控倒塌芯片连接新工艺技术能够在焊膏印刷中实现小节距凸台形成的同时提供相同合金选择的适应性。这种简单的受控倒塌芯片连接新工艺使低成本、高成品率以及快速封装周期的解决方法对于细节距FCiP以及WLCSP凸台形成均能适用。 | Eric Laine Klaus Ruhmer Luc Belanger Michel Turgeon Eric Perfecto Hai Longworth David Hawken | 2007 | 电子工业专用设备2007，36，8： | 0 |
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