|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019，4，4： | 2 |
| 2 | Oral fluoropyrimidine treatment of colorectal cancer显示文摘 | Eng C Kindler H L Schilsky R L | 2001 | Clin Colorectal Cancer2001，1，2： | 1 |
| 3 | Role of osteopontin in induction of monocyte chemoatU-actant proteinl and macrophage inflammation protein 1 beta through the NF-Kappa B and MAPK pathways in rheumatoid arthritis显示文摘 | 2~eng W Li R Pan H | 2009 | Arthritis Rheum2009，60，： | 1 |
| 4 | Phonon density of states of iron up to 153 Gigapascals显示文摘 | Mao H.K Xu J Struzhkin V.V Shu J.F Hemley R.J Sturhahn W Wu M.Y Alp E.E Vocadlo L Alfe D Price G.D Gillan M.J Schwoerer-B(o)hning M H(a)usermann D Eng P Shen G Giefers H Lubbers R Wortmann G | | 0，，： | 1 |
| 5 | Evaluation of antimicrobial activities of Satureja hortensis L.显示文摘 | F ?ahin ? Karaman M Güllüce H ??üt?ü M ?engül A Ad?güzel S ?ztürk R Kotan | 2003 | Journal of Ethnopharmacology2003，，1： | 1 |
| 6 | Use of D2 lactic acid measurement in the diagnosis of bacterial infections显示文摘 | SMITH S M ENG R H K BUCCINI F | 1986 | J Infect Dis1986，154，： | 1 |
| 7 | Studies on untreated and urea-treated rice straw from three cultivation seasons: Histologi- cal investigations by light and scanning electron microscopy 显示文摘 | Shen H S Sundstel F Eng E R | 1999 | Anim Feed Sci Tech1999，80，： | 1 |
| 8 | Glass Transition and Crystallization Phenomena in Epoxidized Trans-Polyisoprene: A Differential Scanning Calorimetry Study显示文摘 | Burfield D R Eng A H | 1989 | Polymer1989，30，11： | 1 |
| 9 | Bactericidal effects of antibiotics on slowly growing and nongrowing bacteria显示文摘 | Eng R H K Padberg F T Smith S M | 1991 | Antimicrobial Agents and Chemothercpy1991，，： | 1 |
| 10 | Use of D-lactic acid measurements in the diagnosis of bacterial infections显示文摘 | Smith S M Eng R H Buccini F | 1986 | J Infect Dis1986，154，4： | 1 |
| 11 | Ultrapyrolysis of propane in a spouted-bed reactor with a draft tube显示文摘 | Stocker R K Eng J H Svrcek W Y | 1989 | JIChE J1989，35，： | 1 |
| 12 | Overview of the HUPO Plasma Proteome Project:results from the pilot phase with 35 collaborating laboratories and multiple analytical groups,generating a core dataset of 3020 proteins and a publicly-available database显示文摘 | Omenn G S States D J Adamski M Blackwell T W Menon R Hermjakob H Apweiler R Haab B B Simpson R J Eddes J S Kapp E A Moritz R L Chan D W Rai A J Admon A Aebersold R Eng J Hancock W S Hefta S A Meyer H Paik Y K Yoo J S Ping P Pounds J Adkins J Qian X Wang R | | 0，，： | 1 |
| 13 | Clindamycin for eolonization and infection by methicillin-resistant Staphylococcus aureus 显示文摘 | Smith S M Mangia A Eng R H | 1988 | Infection1988，16，： | 1 |
| 14 | Use of D-lactic acid measurement in the diagnosis of bacterial infections 显示文摘 | SMITH S M ENG R H BUCCINI F | 1986 | J Infect Dis1986，154，4： | 1 |
| 15 | Use of D-lactic acid measurements in the diagnosis of bacterial infections显示文摘 | Smith S M Eng R H Buccini F | 1986 | J Infect Dis1986，154，： | 1 |
| 16 | Studies on untreated and urea-treated rice straw fro three cultivation seasons: 3 histological investigations by light and scanning electron microscopy 显示文摘 | SHEN H SUNDSTOL F ENG E R | 1999 | Anim Feed Sci Technol1999，80，： | 1 |
| 17 | Studies on untreated and urea-treated rice straw from three cultivation seasons: Histological investigations by light and scanning electron microscopy 显示文摘 | Shen H S Sundstol F Eng E R | 1999 | Animal Feed Science and Technology1999，80，： | 1 |
| 18 | Preparation of BaxSr1-xTiO3 pyroelectric ceramics by sol-gel technique显示文摘 | Eng H R Qu C F Yao C H | 1999 | J Inorg Mater1999，14，1： | 1 |
| 19 | Effect of antibiotics on endotoxin release from gram-negative bacteria显示文摘 | Eng R H K Smith S M Fan-Havard P | 1993 | Diagnostic Microbiology and Infectious Disease1993，16，3： | 1 |
| 20 | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia eoli 显示文摘 | Tsuruta H Paddon C J Eng D Lenihan J R Homing T Anthony L C Regentin R Keasling J D Renninger N S Newman J D | 2009 | PLoS ONE2009，4，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员