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| 1 | The Subcellular Localization and Blue-Light- Induced Movement of Phototropin 1-GFP in Etiolated Seedlings of Arabidopsis thalianaw显示文摘Phototropin 1 (phot1 ) 是为向光性,叶绿体运动,有气孔的洞,叶扩大,并且响应蓝光的太阳的追踪的一个光敏电阻器。有 PHOT1::GFP 的后面的更早的工作(Sakamoto 和布里格斯, 2002 ) ,我们调查了模式细胞并且在 34 d 的 phot1 的 subcellular 本地化 Arabidopsis thalinana 的旧变白的幼苗。是从本国的在上游的序列表示了, PHOT1::GFP 熔化蛋白质在子叶的离开轴心的纸巾并且在胚轴的伸长的区域强烈被表示。它中等在根顶附近在射击 / 根转变地区并且在房间被表示。一个荧光信号在根外皮,根帽子,和根是无法发现的顶端的分裂组织本身。子叶边缘附近的叶肉房间的血浆膜显得一致地标记但是跨墙由最近的房间部门创造了更强烈被标记。单个房间类型标记的模式与房间类型和发展舞台变化。蓝光的处理原因 PHOT1::GFP,均匀地相对开始在血浆膜散布了,与强烈标记的有小斑点的区域和完全缺乏在胚轴延伸区域在外皮的房间观察的 fluorescencea 现象最好的另外的区域重新组织变得进不同马赛克。伴随物与或追随者这个重组,进在所有房间类型的细胞质的 PHOT1::GFP 行动除了警卫房间调查了。它在黑暗在几个小时以后由未辩别出的机制从细胞质消失。它在细胞质的外观也不它在黑暗的最终的消失被翻译禁止者酮环己酰亚胺也不阻止,尽管后者过程被延迟。我们假设那 blue-light-induced phot1 重新本地化调制 blue-light-activated 信号 transduction。 | Ying-Lang Wan William Eisinger David Ehrhardt Ulrich Kubitscheck Frantisek Baluska Winslow Briggs | 2008 | Molecular Plant2008，1，1： | 10 |
| 2 | Microtubules Are Essential for Guard-Cell Function in Vicia and Arabidopsis显示文摘放射状地安排的外皮的微导管是警卫房间的一个突出的特征。表示 GFP 导管素的警卫房间在微导管的外观看了一致变化 stomata 什么时候开了或关门。当 stomata 关门了,警卫房间显示出更少微导管结构,是否由转移导致了到黑暗,骆驼毛的织物,氢过氧化物,或钠氢碳酸盐。警卫房间不知(关上的 stomata ) 在轻处理上在微导管结构和有气孔的孔显示出增加。GFP-EB1,标记加结束成长的微导管,没在有气孔的闭合上在汇编的正结束或速度的数字显示出变化。因为当微导管结构数字衰退了时,加结束和正结束的生长的率成长的数字没变化,微导管不稳定性或重新整理一定为微导管的明显的损失负责。当外皮的微导管变得拆卸,有关上的 stomata 的警卫房间与开的 stomata 比那些显示出更多的 cytosolic GFP 荧光,尽管与在全部的荧光的大网损失。指向微导管的药在 Vicia 和 Arabidopsis 堵住了警卫房间功能。Oryzalin 破坏了警卫房间微导管并且阻止了有气孔的开和 taxol 稳定的警卫房间微导管和推迟的有气孔的闭合。煤气的交换大小显示为荧光灯标签的蛋白质的 transgenes 没破坏正常有气孔的功能。在微导管与我们的禁止者研究相结合的警卫房间的这些动态变化在警卫房间功能为微导管的一个活跃角色提供证据。 | William Eisinger David Ehrhardt Winslow Briggs | 2012 | Molecular Plant2012，5，3： | 9 |
| 3 | Quantitative Changes in Microtubule Distribution Correlate with Guard Cell Function in Arabidopsis显示文摘放射状地安排的外皮的微导管是警卫房间的一个突出的特征。我们观察了与共焦的显微镜学表示 GFP 导管素(GFP-TUA6 ) 的警卫房间并且当时,在微导管的外观发现了可认识的变化开或靠近的 stomata (Eisinger 等, 2012 ) 。在现在的学习,荧光分发的分析作为 stomata 在警卫房间以内在微导管捆的山峰紧张显示出戏剧的增加开。这增加随能被归因于 polymerized 导管素的全部的荧光的增加被相关。邻近的人行道房间没在山峰紧张或综合荧光看类似的变化有气孔的孔什么时候变化了。标注 RFP 的结束绑定蛋白质 1 的成像(EB1 ) 和在一样的房间表示的标注 YFP 的导管素表明有种结束的微导管的数字仍然保持不变,尽管 polymerized 导管素的全部的数量是更高的在比在关上的警卫房间开。一起拿,这些结果显示在微导管的变化穿被相关与并且为正常要求警卫房间功能被变化在聚类的微导管或捆绑描绘的组织。 | William R. Eisinger Viktor Kirik Charlotte Lewis David W. Ehrhardt Winslow R. Briggs | 2012 | Molecular Plant2012，5，3： | 4 |
| 4 | Adipose tissue fibrosis显示文摘The increasing prevalence of obesity causes a major interest in white adipose tissue biology.Adipose tissue cells are surrounded by extracellular matrix proteins whose composition and remodeling is of crucial importance for cell function.The expansion of adipose tissue in obesity is linked to an inappropriate supply with oxygen and hypoxia development.Subsequent activation of hypoxia inducible factor 1(HIF-1) inhibits preadipocyte differentiation and initiates adipose tissue fibrosis.Thereby adipose tissue growth is limited and excess triglycerides are stored in ectopic tissues.Stressed adipocytes andhypoxia contribute to immune cell immigration and activation which further aggravates adipose tissue fibrosis.There is substantial evidence that adipose tissue fibrosis is linked to metabolic dysfunction,both in rodent models and in the clinical setting.Peroxisome proliferator activated receptor gamma agonists and adiponectin both reduce adipose tissue fibrosis,inflammation and insulin resistance.Current knowledge suggests that antifibrotic drugs,increasing adipose tissue oxygen supply or HIF-1 antagonists will improve adipose tissue function and thereby ameliorate metabolic diseases. | Christa Buechler Sabrina Krautbauer Kristina Eisinger | 2015 | World Journal of Diabetes2015，6，4： | 3 |
| 5 | 新型HK750PT推管机用于阿姆河的穿越工程显示文摘本文详细介绍了采用水平定向钻进和直推铺管联合施工法穿越阿姆河铺设56”天然气管道的工程情况,包括工程的地质情况、施工过程和造斜施工等。 | J. Himmerich A. Groβmann M. Lubberger J. Eising 程国亮(译) | 2011 | 非开挖技术2011，，1： | 2 |
| 6 | Designing piping systems against acoustically induced structural fatigue显示文摘 | EISINGER F L | 1997 | Journal of Pressure Vessel Technology1997，119，3： | 1 |
| 7 | Selective proliferation of normal human melanocytes in vitro in the presence of phorbol easter and cholera toxin显示文摘 | Eisinger M Marco O | 1982 | Proc Natl Acad Sci USA1982，79，： | 1 |
| 8 | Adiponectin up-regulates hepatocyte CMKLR1which is reduced in human fatty liver显示文摘 | Wanninger J Bauer S Eisinger K | 2012 | Mol Cell Endocrinol2012，349，2： | 1 |
| 9 | The Conditions of Political Protest Behavior in American Cities 显示文摘 | Eisinger Peter | 1973 | American Political Science Review1973，67，1： | 1 |
| 10 | Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis显示文摘 | D. Grunberger R. Banerjee K. Eisinger E. M. Oltz L. Efros M. Caldwell V. Estevez K. Nakanishi | 1988 | Experientia1988，，3： | 1 |
| 11 | Retinoic acid inhibits beta-catenin through suppression of Cox-2 : a role for truncated adenomatous polyposis coli 显示文摘 | Eisinger Air Nadauld LD Shelton DN | 2007 | J Biol Chem2007，282，29： | 1 |
| 12 | Effect of mifepristone for symptomatic leiomyomata on quality of life and uterine size显示文摘 | Fiscella K Eisinger S H Meldrum S | 2006 | Obstet Gynecol2006，108，6： | 1 |
| 13 | APC truncation and increased β-catenin levels in a human breast cancer cell line显示文摘 | Schlosshauer P W Brown S A Eisinger K | 2000 | Carcinogenesis2000，21，7： | 1 |
| 14 | Chronic morphine treatment inhibits opioids receptor desensitization and internalization显示文摘 | Eisinger DA Ammer H Schulz R | 2002 | J Neurosci2002，22，10： | 1 |
| 15 | Site- and gender-specific time trend analyses of the incidence of skin melanomas in the former German Democratic Republic (GDR) including 19351 cases 显示文摘 | Stang A Stabenow R Eisinger B | 2003 | Eur J Cancer2003，39，11： | 1 |
| 16 | Selectine poliferation of normal human melano- cytes in vitro in the presence of phorbol ester and cholera toxin 显示文摘 | Eisinger M Marko O | 1982 | Proc Natl Aead Scl USA1982，79，8： | 1 |
| 17 | The effects of statin therapy on inflammatory cytokines in patients with bacterial infections:a randomized double-blind placebo controlled clinical trial显示文摘 | Novack V Eisinger M Frenkel A | | 0，，07： | 1 |
| 18 | The effects of statin therapy on inflammatory cytokines in patients with bacterial infections:a randomized double-blind placebo controlled clinical trial显示文摘 | Novack V Eisinger M Frenkel A | 2009 | Intensive Care Med2009，35，7： | 1 |
| 19 | Chronic morphine treatment inhibits opioid receptor desensitization and internalization显示文摘 | Ammer H Schulz R | 2002 | J Neurosci2002，22，10： | 1 |
| 20 | Cultural basis for differences between US and French clinical recommendations for women at increased risk of breast and ovarian cancer显示文摘 | Eisinger F Geller G Burke W | 1999 | Lancet1999，353，9156： | 1 |
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