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| 1 | Effects of Bacillus subtilis CSL2 on the composition and functional diversity of the faecal microbiota of broiler chickens challenged with Salmonella Gallinarum显示文摘Background: The chicken gastrointestinal tract contains a diverse microbiota whose composition and structure play important roles in gut functionality. In this study, microbial shifts resulting from feed supplementation with Bacillus subtilis CSL2 were evaluated in broilers challenged and unchallenged with Salmonella Gallinarum. To analyse bacterial community composition and functionality, 454 GS-FLX pyrosequencing of 16 S r RNA gene amplicons was performed.Results: The Quantitative Insights into Microbial Ecology(QIIME) pipeline was used to analyse changes in the faecal microbiota over a 24-h period. A total of 718,204 sequences from broiler chickens were recorded and analysed. At the phylum level, Firmicutes, Bacteroidetes, and Proteobacteria were the predominant bacterial taxa. In Salmonellainfected chickens(SC), Bacteroidetes were more highly abundant compared to control(NC) and Bacillus-treated(BT)chickens. At the genus level, in the NC and BT groups, Lactobacil us was present at high abundance, and the abundance of Turicibacter, unclassified Enterobacteriaceae, and Bacteroides increased in SC broilers. Furthermore, taxon-independent analysis showed that the SC and BT groups were compositional y distinct at the end of the 24-h period. Further analysis of functional properties showed that B. subtilis CSL2 administration increased gut-associated energy supply mechanisms(i.e. carbohydrate transport and metabolism) to maintain a stable microbiota and protect gut integrity.Conclusions: This study demonstrated that S. Gallinarum infection and B. subtilis CSL2 supplementation in the diet of broiler chickens influenced the diversity, composition, and functional diversity of the faecal microbiota. Moreover, the findings offer significant insights to understand potential mechanisms of Salmonel a infection and the mode of action of probiotics in broiler chickens. | Ju Kyoung Oh Edward Alain B.Pajarillo Jong Pyo Chae In Ho Kim Dong Soo Yang Dae-Kyung Kang | 2017 | Journal of Animal Science and Biotechnology2017，8，2： | 6 |
| 2 | Venous thromboembolism prophylaxis in hospitalized elderly patients: Time to consider a 'MUST' strategy显示文摘静脉的 thromboembolism ( VTE )是可防止的死亡在的最普通的原因 patients.Elderly 就医了病人因为 comorbidities 和在老病人的 VTE 的尖锐 illnesses.Clinical 诊断是的预先安排的高流行,有 VTE 的更高的风险特别地困难并且,这样足够的 VTE 预防具有在减少 VTE 预防的 VTE.Omission 的死亡和病态的枢轴的重要性然而,尽管有连续 education.A 。 | Kwok M Ho Edward Litton | 2011 | Journal of Geriatric Cardiology2011，8，2： | 6 |
| 3 | The reference genetic linkage map for the multinational Brassica rapa genome sequencing project显示文摘 | Su Ryun Choi Graham R. Teakle Prikshit Plaha Jeong Hee Kim Charlotte J. Allender Elena Beynon Zhong Yun Piao Pilar Soengas Tae Ho Han Graham J. King Guy C. Barker Paul Hand Derek J. Lydiate Jacqueline Batley David Edwards Dal Hoe Koo Jae Wook Bang Beom-Se | 2007 | Theoretical and Applied Genetics2007，，6： | 2 |
| 4 | Aesthetic Considerations in Understanding Chinese Literati Musical Behaviours 显示文摘 | Ho Edward | 1997 | British Journal of Ethnomusicology 61997，39，： | 1 |
| 5 | Analyses of Three-dimensional Eddy Current Field and Thermal Problems in an Isolated Phase Bus显示文摘 | HO S L LI Y EDWARD W C | 2003 | IEEE Transactions on Magnetics2003，39，3： | 1 |
| 6 | Elevated tumour marker CA19-9:clinical interpretation and influence of obstructive jaundice显示文摘 | Mann DV Edwards R Ho S | | 0，，05： | 1 |
| 7 | Universal alignment probabilities and subset selection for ordinal optimization显示文摘 | Edward T W Ho Y C | 1997 | Journal of Optimization Theory and Applications1997，93，3： | 1 |
| 8 | Elevated tumor marker-CA199 Clinical interpretation and influence of obstructive jaundice显示文摘 | Mann D V Edwards R Ho S | 2000 | Eur J Surg Ocol2000，26，： | 1 |
| 9 | Supply chain knowledge management : A literature review 显示文摘 | Marra M Ho W Edwards J S | 2012 | Expert Systems with Applications2012，39，5： | 1 |
| 10 | Elevated tumour marker CA19-9: clinical interpretation and influence of obstructive jaundice显示文摘 | DV Mann R Edwards S Ho WY Lau G Glazer | 2000 | European Journal of Surgical Oncology2000，，5： | 1 |
| 11 | Long-Term Use of Aspirin and the Risk of Gastrointestinal Bleeding显示文摘 | Edward S. Huang Lisa L. Strate Wendy W. Ho Salina S. Lee Andrew T. Chan | 2011 | The American Journal of Medicine2011，，5： | 1 |
| 12 | Characterization of ionotripic glutamate receptor mediated nitric oxide production in rats显示文摘 | Edward HO Robert JB | 1997 | J Neurosurg1997，40，4： | 1 |
| 13 | Elevated tumour marker CA19 -9: clinical interpretation and influence of obstructive jaundice 显示文摘 | Mann DV Edwards R Ho S | 2000 | Eur J Surg Oncol2000，26，5： | 1 |
| 14 | Universal alignment probabilities and subset selection for ordinal optimization显示文摘 | T W Edward Lau Y C Ho | 1997 | Journal of Optimization Theory and Applications1997，93，3： | 1 |
| 15 | Universal alignment probabilities and subset selection for ordinal optimization显示文摘 | Edward L T W Ho Y C | 1997 | Journal of Optimization Theory and Applications1997，93，3： | 1 |
| 16 | Universal alignment probabilities and subset selection for ordinal optimization显示文摘 | Edward Lau T W Ho Y C | 1997 | Optimization Theory and Applications1997，97，3： | 1 |
| 17 | Explanation of Goal Softening in Ordinal Optimization 显示文摘 | Loo Hay lee Tak Wing Edward Lau Yu Chi Ho | 1999 | IEEE Trans on Automatic Control1999，44，1： | 1 |
| 18 | Universal Alignment Probabilities and Subset Selection for Ordinal Opti- mization 显示文摘 | Edward Lau T W Ho Y C | 1997 | Journal of Optimization Theory and Applications1997，93，3： | 1 |
| 19 | Use of Chlorhexidine-impregna- ted Dressing to Prevent Vascular and Epidural Catheter Colo- nization and Infection: A Meta analysis显示文摘 | Kwok M Ho Edward Litton | 2006 | Journal of Antimi- crobial Chemotherapy2006，58，： | 1 |
| 20 | Wound protectors reduce surgical site infection: a recta-analysis of randomized con- trolled trials 显示文摘 | Edwards JP Ho AL Tee MC | 2012 | Ann Surg2012，256，1： | 1 |
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