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| 1 | Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice显示文摘雌激素缺乏调停变老,但是内在的机制尚待充分坚定。我们这里报导 aromatase 的指向的混乱在老鼠引起的雌激素缺乏在 vivo 在肾上腺导致 telomerase 活动的重要抑制。基因表示分析证明当雌激素不在时, telomerase 颠倒 transcriptase (TERT ) 基因表示在肾上腺外皮和肾的萎缩与损害房间增长联合被减少。在 c 工具包积极的干细胞被识别在肾的外皮的实质占据。telomeres 的分析表明那雌激素缺乏比那在肾的外皮导致显著地更短的 telomeres 在野类型(WT ) 控制鼠标。为了推进,建立雌激素的原因的效果,我们在这些雌激素缺乏的动物进行了雌激素代替治疗。为 3 个星期的雌激素的管理在雌激素缺乏的老鼠恢复 TERT 基因表示, telomerase 活动和房间增长。因此,我们第一次,那雌激素缺乏在 vivo 在鼠标的肾上腺引起 TERT 基因表示, telomerase 活动, telomere 维护,和房间增长的抑制的数据表演,建议那 telomerase 抑制并且 telomere 弄短可以调停在肾上腺的房间增长拘捕,因此贡献雌激素在生理的条件下面的导致缺乏的老化。 | Sharyn Bayne Margaret EE Jones He Li Alex R Pinto Evan R Simpson Jun-Ping Liu | 2008 | Cell Research2008，18，11： | 6 |
| 2 | C35 (C17ori37) isa novel tumor biomarker abundantly expressed in breast cancer显示文摘 | EVANS EE HENN A D JONASON A | 2006 | Mol Cancer Ther2006，5，11： | 1 |
| 3 | Effect of reducing interns'work hours on serious medical errors in intensive care units显示文摘 | Lockley SW Cronin JW Evans EE | 2004 | N Engl J Med2004，351，： | 1 |
| 4 | C35(C17orf37)is a no-vel tumor biomarker abundantly expressed in breast cancer显示文摘 | Evans EE Henn AD Jonason A | 2006 | Mol Cancer Ther2006，5，： | 1 |
| 5 | LCAT modulates atherogenic plasma lipoproteins and the extend of atherosclerosis only in the presence of normal LDL receptor in transgenic rabbits显示文摘 | Brousseau ME Kauffman RD Herderick EE Demosky SJ Jr Evans W Marcovina S | 2000 | Arterioscler Throm Vasc Biol2000，20，2： | 1 |
| 6 | C35 (C17ort37) is a novel tumor biomark er abundantly expressed in breast cancer 显示文摘 | Evans EE Henn AD Jonason A | 2006 | Mol Cancer Ther2006，5，： | 1 |
| 7 | Epidemiology of Helicobacter pylori infection among 4742 randomly selected subjects from Northern Ireland显示文摘 | Murray LJ Mccrum EE Evans AE | 1997 | Int J Epidemiol1997，26，1： | 1 |
| 8 | Induced bactericidal responses of abalones显示文摘 | Cushing JE Evans EE Evans ML 1971 | 1971 | J Invert Pathol1971，17，： | 1 |
| 9 | Leptin resistance and obesity显示文摘 | Enriori PJ Evans AE Sinnayah P Jobst EE Tonelli-Lemos L Billes SK | 2006 | Obesity (silver spring)2006，14，5： | 1 |
| 10 | Genetics of colon carcinogenesis in mice treated with 1,2-dimethylhydrazine显示文摘 | Evans JT Shows TB Sproul EE | 1977 | Cancer Res1977，37，1： | 1 |
| 11 | Interaction of the glucose tolerance factor(GTF)with insulin显示文摘 | Evans GW Roginksi EE Mertz W | 1973 | Biochem Biophys Res Commun1973，50，3： | 1 |
| 12 | C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast canc- er显示文摘 | Evans EE Henn AD Jonason A | 2006 | Mol Cancer Ther2006，5，： | 1 |
| 13 | Interaction of the glucose tolerance factor (GTF) with insulin显示文摘 | Evans GW Ropginksi EE Mertz W | 1973 | Biochem Biophs Res Commun1973，50，3： | 1 |
| 14 | Challenging Theophrastus: A common core list of plant traits for functional ecology显示文摘 | Evan Weiher Adrie van der Werf Ken Thompson ee al | 1998 | Journal of Vegetation Science1998，10，5： | 1 |
| 15 | Lethality-based selection of recombinant genes in mammalian cells: application to identifying tumor antigens 显示文摘 | Smith ES Mandokhot A Evans EE | 2001 | Nat Med2001，7，8： | 1 |
| 16 | Interaction of the glucose tolerance factor,(GTF) with insulin显示文摘 | EVANS GW ROGINKSI EE MERTZ W | | 0，，03： | 1 |
| 17 | Genetics of colon carcinogenesis in mice treated with 1,2-dimethylhydrazine 显示文摘 | Evans JT Shows TB Sproul EE | 1977 | Cancer Res1977，37，1： | 1 |
| 18 | C35 (C 17orf37 ) is a novel tumor biomarker abundantly expressed in breast cancer 显示文摘 | Evans EE Henn AD Jonason A | 2006 | Mol Cancer Ther2006，5，11： | 1 |
| 19 | C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer显示文摘 | Evans EE Henn AD Jonason A | 2006 | Mol Cancer Ther2006，5，： | 1 |
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