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| 1 | 国际专家组关于超声内镜引导下胰腺囊性肿瘤消融的立场声明显示文摘背景和目的最近,一些有关胰腺囊性肿瘤(pancreatic cystic neoplasms,PCNs)治疗的指南建议已经发表,但是超声内镜(endoscopic ultrasound,EUS)引导下PCNs消融的作用在这些指南中尚未明确。本文的目的是通过提出一系列临床问题并根据可获得的最佳科学证据提供答案来探讨围绕EUS引导下PCNs消融的问题。方法我们从亚洲EUS学组和一个国际专家组中招募了一个EUS引导下PCNs消融专家小组。创建了一个临床问题列表,并将每个问题分配给一个成员以产生一个陈述。然后在2016年10月至2017年10月的三次互联网会议上讨论了这些陈述。之后相互协商对这些陈述进行修改,直到取得协商一致意见。之后,将完整的陈述总结集体发送给所有小组成员,以对陈述的强度进行投票,对陈述进行分类,对证据进行分级。结果制定了关于EUS引导下PCNs的23个陈述。这些陈述涉及操作步骤、操作技术、操作前和操作后管理,并发症的管理以及手术中所需能力和培训。结论在所有内镜学会中,本共识是关于EUS引导下PCNs消融的首篇共识。有兴趣进行这项技术的临床医生应参考这些共识,未来的研究应设法解决本共识中提出的重要问题。 | Anthony Yuen-Bun Teoh DongWan Seo William Brugge John Dewitt Pradermchai Kongkam 令狐恩强(文/译) Matthew T.Moyer JiKon Ryu Khek Yu Ho 杜晨(翻译) 李惠凯(翻译) | 2019 | 中华胃肠内镜电子杂志2019，6，4： | 8 |
| 2 | Cysteine residues of the porcine reproductive and respiratory syndrome virus small envelope protein are non-essential for virus infectivity显示文摘 | Changhee L Dongwan Y | 2005 | Journal of General Virology2005，86，： | 1 |
| 3 | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and their potential as vaccine vectors 显示文摘 | Dongwan Yoo Siao-Kun W Welch Changhee Lee | 2004 | Vet Immunol Immunopathol2004，102，： | 1 |
| 4 | Design of fuzzy power system stabilizer using adaptive evolutionary algorithm显示文摘 | HWANG Gihyun KIN Dongwan LEE Jaehyun | 2008 | Engineering Applications of Artificial Intelligence2008，21，1： | 1 |
| 5 | Nonstrue- tural protein la subunit-based inhibition of NF-B ac- tivation and suppression of interferon-l] production by porcine reproductive and respiratory syndrome virus 显示文摘 | CHENG S PETER K DONGWAN Y | 2010 | Virology2010，407，2： | 1 |
| 6 | Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virus显示文摘 | Cheng Song Peter Krell Dongwan Yoo | 2010 | Virology2010，，2： | 1 |
| 7 | Microstructura/ Interpretation of the Effect of Various Matrices on the Ablation Properties of Carbon-fibe-reinforced Composites显示文摘 | Cho Dongwan Yoon Byung | 2001 | Composites Science and Technology2001，61，3： | 1 |
| 8 | Chronic hypoperfusion due to intracranial large artery stenosis is not associated with cerebralβ-amyloid deposition and brain atrophy显示文摘Background:Insufficient cerebral perfusion is suggested to play a role in the development of Alzheimer disease(AD).However,there is a lack of direct evidence indicating whether hypoperfusion causes or aggravates AD pathology.We investigated the effect of chronic cerebral hypoperfusion on AD-related pathology in humans.Methods:We enrolled a group of cognitively normal patients(median age:64 years)with unilateral chronic cerebral hypoperfusion.Regions of interest with the most pronounced hypoperfusion changes were chosen in the hypoperfused region and were then mirrored in the contralateral hemisphere to create a control region with normal perfusion.11C-Pittsburgh compound-positron emission tomography standard uptake ratios and brain atrophy indices were calculated from the computed tomography images of each patient.Results:The median age of the 10 participants,consisting of 4 males and 6 females,was 64 years(47-76 years).We found that there were no differences in standard uptake ratios of the cortex(volume of interest[VOI]:P=0.721,region of interest[ROI]:P=0.241)and grey/white ratio(VOI:P=0.333,ROI:P=0.445)and brain atrophy indices(Bicaudate,Bifrontal,Evans,Cella,Cella media,and Ventricular index,P>0.05)between the hypoperfused regions and contralateral normally perfused regions in patients with unilateral chronic cerebral hypoperfusion.Conclusion:Our findings suggest that chronic hypoperfusion due to large vessel stenosis may not directly induce cerebralβ-amyloid deposition and neurodegeneration in humans. | Dongyu Fan Huiyun Li Dongwan Chen Yang Chen Xu Yi Heng Yang Qianqian Shi Fangyang Jiao Yi Tang Qiming Li Fangyang Wang Shunan Wang Rongbing Jin Fan Zeng Yanjiang Wang | 2022 | Chinese Medical Journal2022，，5： | 1 |
| 9 | Interaction of the porcine reproductive and respiratory syndrome virus nucleocapsid protein with the inhibitor of MyoD family-a domain-containing protein显示文摘 | Cheng Song Ray Lu Dorothee Bienzle Hsiao-Ching Liu Dongwan Yoo | 2009 | Biological Chemistry2009，，3： | 1 |
| 10 | Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages 显示文摘 | Sarah K W Dongwan Y | 2003 | J Virol2003，77，8： | 1 |
| 11 | Peptide domains involved in the localization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus显示文摘 | Raymond R.R. Rowland Paula Schneider Ying Fang Sarah Wootton Dongwan Yoo David A. Benfield | 2003 | Virology2003，，1： | 1 |
| 12 | The role of porcine reproductive and respiratory syndrome virus (PRRSV) nucleocapsid protein for induction of IL-10 and reg- ulatory T lymphocytes(Treg)显示文摘 | Piya Wongyanin Supranee Buranapraditkul Dongwan Yoo et ol | 2012 | Gen Virol2012，，3： | 1 |
| 13 | Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells显示文摘 | Oekyung Kim Yan Sun Frances W. Lai Cheng Song Dongwan Yoo | 2010 | Virology2010，，2： | 1 |
| 14 | Prevalence of hepatitis E virus antibodies in Canadian swine herds and identification of a novel variant of swine hepatitis E virus显示文摘 | Philip W Yanlong P M Anthony H Anne D Catherine E D Robert M F Yungho Y Marcelo G Carmencita Y Antonio G | 2001 | Clinical and Diagnostic Laboratory Immunology2001，8，6： | 1 |
| 15 | Homo-oligomerization of the porcine reproductive and respiratory syndrome virus nucleocapsid protein and the role of disulfide linkages 显示文摘 | Sarah K Wootton Dongwan Y | 2003 | J Virol2003，77，8： | 1 |
| 16 | A single amino acid change within antigenic domain Ⅱ of the spike protein of bovine coronavirus confers resistance to virus neutralization; clinical and diagnostic laboratory immunology显示文摘 | Dongwan Y Dirk D | 2001 | March2001，8，2： | 1 |
| 17 | The small envelope protein of porcine reproductive and respiratory syndrome virus possesses ion channel protein-like properties显示文摘 | Changhee Lee Dongwan Yoo | 2006 | Virology2006，，1： | 1 |
| 18 | Prevalence of hep atitis E virus antibodies in Canadian swine herds and identification of a novel variant of swine hepatitis E Virus显示文摘 | Dongwan Yoo Philip Willon Yanlong Pei | 2004 | Clinical and Diagnostic Laboratory Immunology2004，8，6： | 1 |
| 19 | The small envelope protein of porcine reproductive and respiratory syndrome virus possesses ion channel protein-like properties 显示文摘 | Lee Changhee Yoo Dongwan | 2006 | Virology2006，355，： | 1 |
| 20 | Prevalence of hepatitis E virus antibodies in canadian swine erds and identification of novel variant of swine hepatitis virus显示文摘 | Dongwan Yoo Philip Willon Yanlong Pei | 2003 | Clinical and Diagnostic Laboratory Immunology2003，8，6： | 1 |
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