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1MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration显示文摘Arora S Ranade AR Tran NL Nasser S Sridhar S Korn RL Ross JT Dhruv H Foss KM Sibenaller Z Ryken T Gotway MB Kim S Weiss GJ 2011中国神经肿瘤杂志2011,9,1:30
2Autoimmune hepatitis:Appraisal of current treatment guidelines显示文摘Autoimmune hepatitis affects patients of all ages and gender, across all geographic regions. Although still rare, its incidence and prevalence are increasing. Genetic predisposition conveyed by human leucocyte antigen is a strong risk factor for the disease and may be responsible in part for the wide variation in presentation in different geographic regions. Our understanding of the underlying pathogenic mechanisms is evolving and may lead to development of more targeted immunotherapies. Diagnosis is based on elevated levels of serum aminotransferases, gamma globulins, autoantibodies and characteristic findings on histology. Exclusion of other causes of chronic hepatitis is important.Although undiagnosed disease is associated with poor outcomes, it is readily treatable with timely immunosuppressive therapy in the majority of patients.International guidelines are available to guide management but there exists a disparity in the standard treatment regimens. This minireview aims to review the available guidelines and summarize the key recommendations involved in management of this complex autoimmune disease.Dhruv Lowe Savio John 2018World Journal of Hepatology2018,10,12:5
3Variability in permeability and integrity of cell membrane and depletion of food reserves in neem(Azadirachta indica) seeds from trees of different age classes显示文摘We quantified cell membrane permeability(electrical conductivityEC,water soluble sugar-WSS,and amino acids-AA)and integrity(phospholipids,α-tocopherol and lipid peroxidation)along with food reserve deterioration(total proteins,total sugar,and total starch)of neem seeds collected from various mother tree age classes and stored for 65days in airtight plastic containers at ambient room temperature(35±5°C).Results show that the activities were higher in fresh seeds(EC267.56-2950.01μS/g,WSS 19.96-19.48 mg/g and AA 5.40-5.35 mg/g)and declined with increasing duration of storage period(EC153.37-195.17μS/g,WSS 3.13-4.17 mg/g and AA 4.29-4.49 mg/g after35 days and EC 144.02-161.56μS/g,WSS 2.06-2.40 mg/g and AA3.98-4.27 mg/g after 65 days of storage).Phospholipids andα-tocopherol were higher in fresh seed(0.073-0.093 OD at 710 nm and0.080-0.105 OD,respectively)and declined as storage duration increased(0.033-0.042 OD at 710 nm and 00.0010-0.0020 OD,respectively).Dead seeds showed reduced amounts of phospholipids and minimum activity ofα-tocopherol(antioxidants).The level of MDA was lower in fresh seeds(0.0066-0.0087 OD at 600-535 nm)and increased as storage duration increased(0.0248-0.0268 OD after 65 days of storage).The higher amount of MDA indicated that seeds died due to rancidity of the oil inside the seed.Neem seed cake was assessed for deterioration of food reserves(total proteins,total sugar,and total starch),concentrations of which were higher in fresh seed and declined as storage duration increased.Germination was higher in fresh seeds and after 65days,no germination was received perhaps due to deterioration of biochemicals in seeds.Patterns of seed deterioration were similar across all seed lots.evendra Kumar Dhruv Kumar Mishra 2014Journal of Forestry Research2014,25,1:4
4Eigentaste: A Constant Time Collaborative Filtering Algorithm显示文摘Ken Goldberg Theresa Roeder Dhruv Gupta Chris Perkins 2001Information Retrieval2001,,2:3
5Healthcare utilization and costs associated with gastroparesis显示文摘AIM To use a national database of United States hospitals to evaluate the incidence and costs of hospital admissions associated with gastroparesis.METHODS We analyzed the National Inpatient Sample Database(NIS)for all patients in whom gastroparesis(ICD-9 code:536.3)was the principal discharge diagnosis during the period,1997-2013.The NIS is the largest publicly available all-payer inpatient care database in the United States.It contains data from approximately eight million hospital stays each year.The statistical significance of the difference in the number of hospital discharges,length of stay and hospital costs over the study period was determined by regression analysis.RESULTS In 1997,there were 3978 admissions with a principal discharge diagnosis of gastroparesis as compared to16460 in 2013(P<0.01).The mean length of stay for gastroparesis decreased by 20%between 1997 and 2013from 6.4 d to 5.1 d(P<0.001).However,during this period the mean hospital charges increased significantly by 159%from$13350(after inflation adjustment)per patient in 1997 to$34585 per patient in 2013(P<0.001).The aggregate charges(i.e.,'national bill') for gastroparesis increased exponentially by 1026%from$50456642±4662620 in 1997 to$568417666±22374060 in 2013(P<0.001).The percentage of national bill for gastroparesis discharges(national bill for gastroparesis/total national bill)has also increased over the last 16 years(0.0013%in 1997 vs 0.004%in2013).During the study period,women had a higher frequency of gastroparesis discharges when compared to men(1.39/10000 vs 0.9/10000 in 1997 and 5.8/10000vs 3/10000 in 2013).There was a 6-fold increase in the discharge diagnosis of gastroparesis amongst type 1 DM and 3.7-fold increase amongst type 2 DM patients over the study period(P<0.001).CONCLUSION The number of inpatient admissions for gastroparesis and associated costs have increased significantly over the last 16 years.Inpatient costs associated with gastroparesis contribute significantly to the national healthcare bill.Further research on cost-effective evaluation and management of gastroparesis is required.Vaibhav Wadhwa Dhruv Mehta Yash Jobanputra Rocio Lopez Prashanthi N Thota Madhusudhan R Sanaka 2017World Journal of Gastroenterology2017,23,24:3
6The impact of technology on the quality-value-loyalty chain: A research agenda显示文摘A. Parasuraman Dhruv Grewal Journal of the Academy of Marketing Science0,,:2
7Customer Experience Management in Retailing: An Organizing Framework显示文摘Dhruv G Michael L Kumar V 2009Journal of Re-tailing2009,85,1:1
8Challenges and Opportunities in Multichannel Customer Management 显示文摘Neslin S A Dhruv G Leghorn R 2005Jour- nal of Service Research2005,9,2:1
9Regulation of FasL/Fas in Human Trophoblasts: Possible Implications for Chorioamnionitis 显示文摘DHRUV R BALKUNDI JUDY A ZIEGLER JON F WATCHKIO 2003Biol Reprod2003,69,69:1
10The Influence of Store Environment on Quality Inferences and Store Image 显示文摘Julie Baker Dhruv Grewal Parasuraman A 1994Journal of the Academy of Marketing Science1994,22,4:1
11Fertilizer management for sustainable production of potato-onion-rice cropping sequence in alluvial soils of Bihar显示文摘DHRUV K SHARMAR R C 2002Indian Journal of Agricultural Science2002,72,:1
12An Empirical Analysis of the Extreme Cherry Picking Behavior of Consumers in the Frequently Purchased Goods Market显示文摘Debabrata Talukdar Dinesh K. Gauri Dhruv Grewal 2010Journal of Retailing2010,,4:1
13SERVCON: development and validation of a multidimensional service convenience scale显示文摘Kathleen Seiders Glenn B. Voss Andrea L. Godfrey Dhruv Grewal 2007Journal of the Academy of Marketing Science2007,,1:1
14Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells显示文摘Brahma N. Singh Dhruv Kumar Sharmila Shankar Rakesh K. Srivastava 2012Biochemical Pharmacology2012,,9:1
15Effects of Price,Brand,and Store Information on Buyers' Product Evaluations显示文摘Dodds William B Kent B Monroe Dhruv Grewel 1991Journal of Marketing Research1991,,:1
16Identifica-tion of photovoltaic source显示文摘Abir Chatterjee Ali Keyhani Kapoor Dhruv 2011IEEE Transactions on Energy Conversion2011,26,3:1
17The effect of store name, brand name and price discounts on con- sumers' evaluations and purchase intentions显示文摘Grewal Dhruv R Krishnan Julie Baker etc 1998Journal of Retailing1998,74,3:1
18Microendoscopic lumbar discectomy: Technique and results of 188 cases显示文摘Kulkarni AG Bassi A Dhruv A 2014Indian Journal of Orthopaedic2014,49,2:1
19Microendoscopic lumbar discec- tomy:Technique and results of 188 cases 显示文摘Kulkami AG Bassi A Dhruv A 2014Indian J Orthop2014,48,1:1
20Retailing research:Past,present,and future显示文摘 2007Journal of Retailing2007,,4:1
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