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| 1 | 从附睾到卵子:CRISP蛋白在哺乳动物受精过程中的作用显示文摘哺乳动物的受精过程涉及精卵结合的很多步骤,是一个非常复杂的过程,其分了机制亟待阐明。此篇综述主要论述了CRISP(富含半胱氨酸的分泌蛋白)作为模型分子在哺乳动物受精过程中的价值。大量的体外实验和基因敲出模型研究显示,附睾内的CRISP1以两种不同的亲和力结合于精子表面,参与精子获能、精子-透明带结合、精卵融合的调控。这些研究成果可以延伸至人类。我们住研究中发现,人类具有与啮齿类同源的CRISP(hCRISP1),同样参与受精过样。CRISP家族的其他成员(睾丸内CRISP2、附挈内CRISP3—4、射精时的CRISP3)也参与了精卵结合的过程,提示同源分子间的相互协同有助于受精的成功。另外,我们的研究显示,CRISP蛋白伴随精子穿越男性及女性生殖管道的全过程。我们推测CRISP不仅参与了受精过程,而且可能成为不育和避孕研究的新靶点。 | Vanina G Da Ros Mariana Weigel Munoz Maria A Battistone Nicolas G Brukman Guillermo Carvajal Ludmila Curci Matlas D Gomez-Elias Debora J Cohen Patricia S Cuasnicu | 2015 | Asian Journal of Andrology2015，17，5： | 5 |
| 2 | Determination of ammonia based on the electro-oxidation of hydroquinone in dimethylformamide or in the room temperature ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide显示文摘 | Debora Giovanelli Marisa C Buzzeo Nathan S Lawrence Christopher Hardacre Kenneth R Seddon Richard G Compton | 2003 | Talanta2003，，： | 1 |
| 3 | Effects of ohmic andconventional heating on anthocyanin degradation during the pro- cessing of blueberry pulp 显示文摘 | Julia R S Debora P J Isabel C T | 2013 | LWT- Food Science and Tech- nology2013，51，： | 1 |
| 4 | Psyehosocial perspectives of the partners of breast cancer patients treated with a mastectomy显示文摘 | Luiza AK Debora S Aretuzza F | 2008 | Cancer Nursing2008，31，4： | 1 |
| 5 | Role of endothelin-1 in neovascularation of ovarian carcinoma 显示文摘 | Debora S Valeriana D C Maria R N | 2000 | Am J Pathol2000，157，5： | 1 |
| 6 | Oxidative stress parameters in blood, liver, and kidney of diabetic rats treated with curcumin and/or insulin显示文摘 | Heloisa Einloft Palma Patrícia Wolkmer Miguel Gallio Marcos M. B. Corrêa Roberta Schmatz Gustavo R. Thomé Luciane B. Pereira Ver?nica S. P. Castro Andréia B. Pereira Andressa Bueno Lizielle S. Oliveira Debora Rosolen Thaís R. Mann Bianca S. Cecco Domingui | 2014 | 2014 (1-2)2014，，1： | 1 |
| 7 | The role of suprafacial oxygen in some perovskites for thecatalytic combustion of soot显示文摘 | DEBORA F NUNZIO R GUIDO S | 2003 | Journal of Catalysis2003，217，2： | 1 |
| 8 | Comparison of intravenous fentanyl analgesia and epidural analgesia for postoperative pain relief显示文摘 | DEBORA H S A JOSEPH C P DAVID K M | 2009 | Masui2009，58，9： | 1 |
| 9 | Exercise tolerance in asympto- matic patients with moderate-severe valvular heart disease and pre served ejection fraction显示文摘 | Olaf S Debora E Ricarda B | 2012 | Arch Med Sci2012，8，6： | 1 |
| 10 | Flow cytometric analysis of an Emiliana huxleyi bloom terminated by viral infection 显示文摘 | Jacquet S Heldal M Debora I R | 2002 | Aquatic Microbial Ecology2002，27，3： | 1 |
| 11 | Safety and tolerability of sitagliptin in patients with type 2 diabetes:a pooled analysis显示文摘 | Debora Williams-Herman Elizabeth Round Arlene S Swern | | BMC Endocrine Disorders0，8，： | 1 |
| 12 | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome 显示文摘 | Ashwini Jeggari Debora S Marks Erik Larsson | 2012 | Bioinformatics2012，28，15： | 1 |
| 13 | Zinc transporter 8 autoanti- bodies in patients with type 1 diabetes from a multiethnic population and their first degree relatives显示文摘 | Debora BA Hanna S Bianca B | 2014 | Arq Bras Endocrinol Metab2014，58，7： | 1 |
| 14 | High-temperature electrochemistry: a review 显示文摘 | Gregory G W Debora G Nathan S L | 2004 | Electroanalysis2004，16，6： | 1 |
| 15 | Reduction of murine mammary tumor metastasis by conjugated linoleicacid显示文摘 | Neil E H Debora L Lwari S et al | 2000 | Cancer Letters2000，150，1： | 1 |
| 16 | Potent synergistic interaction between the Nampt inhibitor AP0866 and the apoptosis activator TRAIL in human leukemia cells 显示文摘 | Gabriele Z Michele C Debora S | 2010 | Experimental Hematology2010，38，： | 1 |
| 17 | Antibacteral effects of carbon nanombes: size does matter显示文摘 | Kang S Herznerg M Debora F | 2008 | Langmuir2008，24，： | 1 |
| 18 | Exercise tolerance in asymptomatic patients with moderate-severe valvular heart disease and preserved ejection fraction 显示文摘 | Olaf S Debora B Ricarda B | 2012 | Arch Med Sci2012，8，6： | 1 |
| 19 | The role of suprafacial oxygen in some perovskites for the catalytic combustion of soot显示文摘 | DEBORA F NUNZIO R GUIDO S | 2003 | Journal of Catalysis2003，217，2： | 1 |
| 20 | Effectiveness of treating ovarian hyper - stimulation syndrome with cabergoline in two patients with Gonadotropin producing pituitary adenomas 显示文摘 | Mirta K Debora L Danilovic S | 2006 | Fertil Steril2006，86，3： | 1 |
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