| 6 | Phytochemicals and cancer chemoprevention显示文摘The unending morbidity and mortality that results from cancer,as well as adverse reactions due to chemotherapy and the enormous economic burden of treatment and hospitalization,advocates for the necessity of chemopreventive measures.Cancer chemoprevention refers to the use of agents capable of reversing,reducing,or slowing down the pathology of cancer at various stages.Fortunately,a few therapeutic drugs with relatively low toxicity(e.g.,tamoxifen,finasteride),and a sparse number of vaccines(hepatitis B,HPV),are used to prevent specific cancers.In the general population,however,therapeutic options for cancer prevention are not common.Nonetheless,it is generally agreed that diet affects the genesis of cancer,and phytochemicals have the capacity of functioning as cancer chemoprevention agents.This is supported by epidemiological studies and clearly documented with animal models designed to mimic human carcinogenesis.Additionally,some public health strategies,such as recommendations for greater consumption of fruits and vegetables,reflect the merits of cancer chemoprevention.Here,we focus on some well-established natural product cancer chemopreventive agents,including resveratrol(grapes),epigallocatechin-3-gallate(green tea),sulforaphane(cruciferous vegetables),anthocyanins(grapes and berries),curcumin(turmeric),silibinin(milk thistle),and lycopene(tomatoes).As aptly demonstrated by genomic analysis and other methods,the mechanistic underpinning is variable and complex.In addition,responses may be mediated through indirect mechanisms,such as interaction with the microbiome.Furthermore,ancillary applications of chemopreventive agents are worthy of consideration,such as management of sequelae induced by chemotherapy.Recognizing the loss of millions of cancer patients every year,it is obvious that negating malignant metastatic conditions remains of paramount importance.In meeting this objective,cancer chemoprevention offers great promise. | Asim Dave Falguni Parande Eun-Jung Park John M.Pezzuto | 2020 | Journal of Cancer Metastasis and Treatment2020，6，1： | 0 |
| 7 | 化石燃料+太阳能=未来发电显示文摘太阳能热发电对人类环境的改善及电力行业的可持续发展,具有重要的战略意义,也是21世纪的一种重要能源产业。文章介绍可再生能源发展与应用的推广瓶颈,重点分析了3种聚焦型太阳热能(CSP)的集热技术及应用情况,提出了将可再生能源技术与传统发电技术相结合,取长补短,是一种切实可行的解决办法。可以预见,未来发电的趋势是将传统的火力发电技术与太阳能热发电技术相结合。 | Dave UgoLini Justin Zachary Hyung Joon Park 徐慧超 | 2009 | 上海电力2009，，6： | 0 |
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