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7篇 您的检索式:作者名="Dasher J"
    题名 作者 年代 出处 被引量
1Chronic hepatitis B infection in pregnancy显示文摘There are no standard guidelines to follow when a patient with chronic hepatitis B infection becomes pregnant or desires pregnancy. Topics to consider include which patients to treat, when to start treatment, what treatment to use and when to stop treatment. Without any prophylaxis or antiviral therapy, a hepatitis B surface antigen and E antigen positive mother has up to a 90% likelihood of vertical transmission of hepatitis B virus(HBV) to child. Standard of care in the United States to prevent perinatal transmission consists of administration of hepatitis B immune globulin and HBV vaccination to the infant. The two strongest risk factors of mother to child transmission(MTCT) of HBV infection despite immunoprophylaxis are high maternal HBV viral load and high activity of viral replication. The goal is to prevent transmission of HBV at birth by decreasing viral load and/or decreasing activity of the virus. Although it is still somewhat controversial, most evidence shows that starting antivirals in the third trimester is effective in decreasing MTCT without affecting fetal development. There is a growing body of literature supporting the safety and efficacy of antiviral therapies to reduce MTCT of hepatitis B. There are no formal recommendations regarding which agent to choose. Tenofovir, lamivudine and telbivudine have all been proven efficacious in decreasing viral load at birth without known birth defects, but final decision of which antiviral medication to use will have to be determined by physician and patient. The antivirals may be discontinued immediately if patient is breastfeeding, or within first four weeks if infant is being formula fed.Jennifer R Lamberth Sheila C Reddy Jen-Jung Pan Kevin J Dasher 2015World Journal of Hepatology2015,7,9:32
2Competitive effects of metal dissolution and passivation modulated by surface structure: An AFM and EBSD study of the corrosion of alloy 22显示文摘Gray J J E1 Dasher B S Orme C A 2006Surface Science2006,600,12:1
3Development of extraction process for uranium from South African gold uranium ores显示文摘Gaudin A M Schuhmann J R Dasher J 1956Mining Engineering1956,8,8:1
4Intensive care unit management of liverrelated coagulation disorders显示文摘Dasher K Trotter J F 2012Crit Care CHn2012,28,3:1
5Study of haemoglobin types in Barbary sheep (Ammotragus lervia)显示文摘Huisman T H J Dasher G A Moretz W H 1968Biochem J1968,107,:1
6Intensive care unit management of liver-related coagulation disorders显示文摘Dasher K Trotter J F 2012Crit Care Clin2012,28,3:1
7Haemovigilance and experience of the serlous hazards of transfusion(SHOT)scheme in the United Kingdom(UK)显示文摘EMLove HJomes Williamson H Cohen A Todd K Soldan J Revill D R Norfolk J Barbara C L J Atterbury DAsher 2001中国输血杂志2001,14,S1:0
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