维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

1篇 您的检索式：作者名="Daofang Ding"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Mash1 efficiently reprograms rat astrocytes into neurons显示文摘To date,it remains poorly understood whether astrocytes can be easily reprogrammed into neurons.Mash1 and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons.In this study,we examined astrocytes from 2-month-old Sprague-Dawley rats,and found that Brn2 was expressed,but Mash1 was not detectable.Thus,we hypothesized that Mash1 alone could be used to reprogram astrocytes into neurons.We transfected a recombinant MSCV-MASH1 plasmid into astrocytes for 72 hours,and saw that all cells expressed Mash1.One week later,we observed the changes in morphology of astrocytes,which showed typical neuronal characteristics.Moreover,β-tubulin expression levels were significantly higher in astrocytes expressing Mash1 than in control cells.These results indicate that Mash1 alone can reprogram astrocytes into neurons.	Daofang Ding Leqin Xu Hao Xu Xiaofeng Li Qianqian Liang Yongjian Zhao Yongjun Wang	2014	Neural Regeneration Research2014，9，1：	2

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费