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28篇 您的检索式：作者名="Dadone B"

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	题名	作者	年代	出处	被引量
1	Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system显示文摘允许的技术内长的基因的特定的规定为基因功能的学习是珍贵的并且在治疗学有大潜力。我们创造了在 CRISPR 上系统,由核酸酶死者 Cas9 (dCas9 ) 蛋白质组成的二部件的 transcriptional 使活跃之物与互补顺序与 transcriptional 激活域和单个指南 RNA (sgRNAs ) 熔化了到基因倡导者。我们证明在 CRISPR 上能高效地以一种悦耳的方式在人和老鼠房间激活外长的记者基因。另外,我们证明在 vivo 的柔韧的记者基因激活能被把系统部件注入老鼠接合子完成。而且,我们证明在 CRISPR 上能激活内长的 IL1RN, SOX2,和 OCT4 基因。最有效的基因激活被对近似倡导者有约束力的 3-4 sgRNAs 的簇完成,建议他们在基因正式就职的 synergistic 行动。显著地,当指向多重基因的 sgRNAs 同时被介绍进房间时,柔韧的多路的内长的基因激活被完成。染色体宽的表示介绍表明了系统的高特性。	Albert W Cheng Haoyi Wang Hui Yang Linyu Shi Yarden Katz Thorold W Theunissen Sudharshan Rangarajan Chikdu S Shivalila Daniel B Dadon Rudolf Jaenisch	2013	Cell Research2013，23，10：	65
2	Ghost-cell method with far field coarsening and mesh adaptation for Cartesian grids 显示文摘	DADONE A GROSSMAN B	2006	Computers & Fluids2006，35，7：	1
3	Ghost-Cell method for inviscid two-dimensional flows on cartesian grids 显示文摘	DADONE A GROSSMAN B	2004	AIAA Journal2004，42，12：	1
4	Ghost-cell method for inviscid three-dimensional flows on cartesian grids 显示文摘	DADONE A GROSSMAN B	2007	Computers & Fluids2007，36，10：	1
5	Progressive optimization of in verse fluid dynamic design problem显示文摘	Dadone A Grissman B	2000	Computers and Fluids2000，29，1：	1
6	Ghost-cell method for inviscid two-dimensional flows on Cartesian grids显示文摘	Dadone A Grossman B	2004	AIAA Jour- nal2004，42，24：	1
7	Surface boundary conditions for the numerical solution of the Euler equations in three di- mensions 显示文摘	Dadone A Grossman B	1995	Lecture Notes in Physics1995，453，：	1
8	Ghost-cell method for inviscid two-dimensional flows on cartesian grids 显示文摘	DADONE A GROSSMAN B	2004	AIAA JOUR- NAL2004，42，12：	1
9	Ghost-Cell method with far field coarsening and mesh adaptation for Cartesian grids 显示文摘	Dadone A Grossman B	2006	Computers & Fluids2006，35，7：	1
10	An immersed body methodology for inviscid flows on Cartesian grids显示文摘	Dadone A Grossman B	2002	AIAA paper2002，1059，：	1
11	Ghost-cell method with far field coarsening and mesh adaptation for Cartesian grids 显示文摘	DADONE A GROSSMAN B	2006	Computers & Fluids2006，35，7：	1
12	Ghost-cell method for inviscid three-dimensional flows on cartesian grids 显示文摘	DADONE A GROSSMAN B	2007	Computers & Fluids2007，36，10：	1
13	Surface boundary conditions for the numerical solution of the Euler equations显示文摘	Dadone A Grossman B	1994	AIAA journal1994，32，2：	1
14	Ghost-cell method for inviscid two-dimensional flows on Cartesian grids显示文摘	Dadone A Grossman B	2004	AIAA Journal2004，42，12：	1
15	Surface boundary conditions for the numerical solution of the Euler equations in three di- mensions显示文摘	Dadone A Grossman B	1995	Lect Notes Phys1995，453，：	1
16	Ghost-cell method with far field coarsening and mesh adaptation for Cartesian grids 显示文摘	Dadone A Grossman B	2006	Computers & Fluids2006，35，7：	1
17	Surface Boundary Conditions for the Numerical Solution of the Euler Equations 显示文摘	Dadone A Grossman B	1994	AIAA Journal1994，32，2：	1
18	Ghost- Cell Method for Analysis of Inviscid Three- Dimensional Flows on Cartesian- grids 显示文摘	Dadone A Grossman B	2007	Computers&Fluids2007，36，：	1
19	Ghost cell method for inviscid two-dimensional flows on cartesian grids显示文摘	DADONE A GROSSMAN B	2004	AIAA Journal2004，42，12：	1
20	A renal metanephric adenoma showing both a 2p16e24 deletion and BRAF V600E mutation:a synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation显示文摘	Dadone B Ambrosetti D Carpentier X	2013	Cancer Genet2013，206，910：	1

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