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| 1 | Use of probiotics for prevention of radiation-induced diarrhea显示文摘AIM: To investigate the efficacy of a high-potency probiotic preparation on prevention of radiation-induced diarrhea in cancer patients. METHODS: This was a double-blind, placebo-controlled trial. Four hundred and ninety patients who underwent adjuvant postoperative radiation therapy after surgery for sigmoid, rectal, or cervical cancer were assigned to either the high-potency probiotic preparation VSL#3 (one sachet t.i.d.,) or placebo starting from the first day of radiation therapy. Efficacy endpoints were incidence and severity of radiation-induced diarrhea, daily number of bowel movements, and the time from the start of the study to the use of loperamide as rescue medication. RESULTS: More placebo patients had radiation-induced diarrhea than VSL#3 patients (124 of 239 patients, 51.8%, and 77 of 243 patients, 31.6%; P < 0.001) and more patients given placebo suffered grade 3 or 4 diarrhea compared with VSL#3 recipients (55.4% and 1.4%, P < 0.001). Daily bowel movements were 14.7 ± 6 and 5.1 ± 3 among placebo and VSL#3 recipients (P < 0.05), and the mean time to the use of loperamide was 86 ± 6 h for placebo patients and 122 ± 8 h for VSL#3 patients (P < 0.001). CONCLUSION: Probiotic lactic acid-producing bacteria are an easy, safe, and feasible approach to protect cancer patients against the risk of radiation-induced diarrhea. | P Delia G Sansotta V Donato P Frosina G Messina C De Renzis G Famularo | 2007 | World Journal of Gastroenterology2007，13，6： | 29 |
| 2 | Tumor-necrosis-factor stimulates ornithine decarboxylase activity in human fibroblasts and tumor target-cells显示文摘 | Donato N J Rotbein J Rosenblum M G | 1991 | Journal of Cellular Biochemistry1991，46，： | 2 |
| 3 | Analysis of UbcH10 expression represents a useful tool for the diagnosis and therapy of astrocytic tumors 显示文摘 | DONATO G IOFRIDA G LAVANO A | 2008 | Clin Neuropathol2008，27，4： | 1 |
| 4 | Classifying facial actions显示文摘 | Donato G Bartlett M S Hager J C | 1999 | IEEE Transactions on Pattern Analysis and Machine Intelligence1999，21，10： | 1 |
| 5 | Is carotid artery stenting in octogenarians really dangerous显示文摘 | Setacci C de Donato G Chisci E | | 0，，03： | 1 |
| 6 | Two years of a fungal aerobioeontamination survey in a Florentine haematology ward显示文摘 | Pini G Donato R Faggi E | 2004 | Eur J Epidemiol2004，19，7： | 1 |
| 7 | Surgical management of acute carotid thrombosis after carotid stenting: a report of three eases显示文摘 | Setacci C de Donato G Setacci F | 2005 | J Vase Surg2005，42，5： | 1 |
| 8 | Anterior and posterior facial nerve rerouting:a comparative study显示文摘 | Rosso A Piccirillo E De Donato G | 2003 | Skull Base2003，13，3： | 1 |
| 9 | Neutrophil gela- tinase-associated Iipocalin(NGAL) as a marker of kidney damage显示文摘 | olignano D Donato V Coppolino G | 2008 | Am J Kidney Dis2008，52，3： | 1 |
| 10 | S100B's double life:intracellular regulator and extracellular signal显示文摘 | Donato R Sorci G Riuzzi F | 2009 | Biochirn Biophys Acta2009，1793，6： | 1 |
| 11 | Selectivity hydrogenation of benzene to cyclohexene on Ru/γ-Al2O3显示文摘 | MILONE C NERI G DONATO A MUSOLINO M G MERCADANTE L | 1996 | J Catal1996，159，2： | 1 |
| 12 | Occurrences at the mineral-bacteria interface during the oxidation of arsenopyrite by Thiobacillusferrooxidans 显示文摘 | Monroy M G Mustin C Donato P | 1995 | Biotechnology and Bioengineering1995，46，： | 1 |
| 13 | Neutrophil gelatinase- associated lipocalin (NGAL) as a marker of kidney damage显示文摘 | Bolignano D Donato V Copp01ino G | 2011 | Am J Kidney Dis2011，52，3： | 1 |
| 14 | Safety and feasibility of intravascular optical coherence tomography using a nonocclusive technique to evaluate carotid plaques before and after stent deployrnentj显示文摘 | Setacci C de Donato G Setacci F | 2012 | J Endovascular Ther2012，19，3： | 1 |
| 15 | Acid gelation in heated and unheated milks: inter acttions between serum protein complexes and the surfaces of casein micelles 显示文摘 | Donato L Alexander M Dalgleish D G | 2007 | Journal of Agricultural and Food Chemistry2007，55，： | 1 |
| 16 | Photovoltaic properties of multi-walled carbon nanotubes deposited on n-doped silicon 显示文摘 | Arena A Donato N Saitta G | 2008 | Microelectron J2008，39，12： | 1 |
| 17 | Subintimal angioplasty with the aid of a re-entry device for TASC C and D lesions of the SFA显示文摘 | Setacci C Chisci E de Donato G | 2009 | EurJ Vasc Endovasc Surg2009，38，： | 1 |
| 18 | Facial reanimation after facial nerve injury using hypoglossal to facial nerve anastomosis: the gmppo otologico experience 显示文摘 | Tanbouzi HS Kumar DV De Donato G | 2013 | Indian J Otolaryngol Head Neck Surg2013，65，4： | 1 |
| 19 | Neutrophil gelatinase-associated lipocalin (NGAL) as a marker of kidney damage 显示文摘 | Bolignano D Donato V Coppolino G | 2008 | Am J Kidney Dis2008，52，3： | 1 |
| 20 | Total anomalous pulmonary venous connection:long-term appraisal with evolving technical solutions显示文摘 | Michielon G Di Donato RM Pasquini L | 2002 | Eur J Cardiothorac Surg2002，22，2： | 1 |
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