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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | A parallel sort merge JOIN algorithm for managing data skew显示文摘 | Wolf J L Dias D M Yu P S | 1993 | IEEE Transactions Parallel and Distributed Systems1993，4，1： | 2 |
| 3 | Inorganic ceramic/polymer ferroe lectric composite electrets 显示文摘 | DIAS C J DAS-Gupta D K | 1996 | IEEE Trans Dielectr Electr Insul1996，3，5： | 1 |
| 4 | Solution conformation of brazzein by 1H nuclear magnetic resonance:resonance assignent and secondary structure 显示文摘 | Dia J X Ming D | 1999 | International Journal of Biological Macromolecules1999，24，： | 1 |
| 5 | Ultrasound-guided retrograde intubation显示文摘 | Vieira D Lages N Dias J | 2013 | Anaesthesia2013，68，10： | 1 |
| 6 | Properties of Ni/YSZ porous cermets for SOFC by tape casting and coat-mix process 显示文摘 | SIMWONIS D THULEN H DIAS F J | 1999 | J Mater Proc Tech1999，92，93： | 1 |
| 7 | The effectiveness of a home care program for supporting caregivers of persons with dementia in developing countries: a randomised controlled tri- al from Goa, India显示文摘 | Dias A Dewey ME D Souza J | 2008 | Plos ONE2008，3，6： | 1 |
| 8 | Characterization of clifferent fruit wines made from cacao,cupuassu,gabiroba,jaboticaba and umbu 显示文摘 | DUARTE W F DIAS D R OLWEIRA J M | 2010 | LWT - Food Science and Teclmology2010，43，10： | 1 |
| 9 | MyoDl proteine expression in alveolar soft part sarcoma as confirmatory evidence of its skeletal muscle nature显示文摘 | ROSAI J DIAS P PARHAM D M | 1991 | Am J Surg Pathol1991，15，： | 1 |
| 10 | A parallel sort merge join algorithm for managing data skew显示文摘 | Wolf J L Dias D M Yu P S | 1993 | IEEE Trans on Parallel and Distributed System1993，4，1： | 1 |
| 11 | Learning by feeling: evoking empathy with synthetic characters 显示文摘 | Paiva A Dias J Sobral D | 2005 | Applied Artificial Intelligence2005，19，34： | 1 |
| 12 | Towards Software Architecture-based Regression Testing显示文摘 | Muccini H Dias M Richardson D J | 2005 | ACM SIGSOFT Software Engineering Notes2005，30，4： | 1 |
| 13 | Materials Characterization in Support of the Development of an Anode Substrate for Solid Oxide Fuel Cells显示文摘 | Maoumidis A Dias F J | 1997 | J Mater Research1997，12，6： | 1 |
| 14 | Material characterization in support of the development of an anode substrate for solid oxide fuel cells显示文摘 | Simwonis D Maoumidis A Dias F J | 1997 | J Mater Reseach1997，12，6： | 1 |
| 15 | Production planning optimization for manufacturing and remanufacturing system in stochastic environment 显示文摘 | Naeem M A Dias D J Tibrewal R | 2013 | Journal of Intelligent Manufacturing2013，24，4： | 1 |
| 16 | Molecular, structural, and cellular biology of follitropin and follitropin receptor 显示文摘 | DIAS J A COHEN B D LINDAU-SHEPARD B | 2002 | Vitamins and Hormones-ad- vances in Research and Applications2002，64，： | 1 |
| 17 | Biodiversity meets the atmosphere:A global view of forest canopies显示文摘 | Ozanne C M P Anhuf D Boulter S L Keller M Kitching R L Korner C Meinzer F C Mitchell A W Nakashizuka T Dias S Stork N E Wright S J Yoshimura M | | 0，，： | 1 |
| 18 | The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit显示文摘 | Dias A Bouvier D Crépin T McCarthy A A Hart D J Baudin F Cusack S Ruigrok R W | 2009 | Nature2009，458，7240： | 1 |
| 19 | Can we improve gait skills in chronic hemiplegics? A randomised control trial with gait trainer显示文摘 | Dias D Lains J Pereira A | 2007 | Eura Medicophys2007，43，4： | 1 |
| 20 | Effects of activated char- coal on Brassica oleracea microspore culture embryogenesis显示文摘 | Carlos J Dias D S | 1999 | Euphytica1999，，08： | 1 |
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