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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Mineralogy and geochemistry of hydrothermal sediments from the serpentinite-hosted Saldanha hydrothermal field ( 36°34' N ; 33 ° 26' W) at MAR 显示文摘 | Dias A S Barriga F J | 2006 | Marine Geology2006，225，： | 1 |
| 3 | Efficacy of CFRP- based techniques for the flexural and shear strengthening of concrete beams 显示文摘 | Barros J A O Dias S J E Lima J 1 T | 2007 | Cement and Concrete Composites2007，29，3： | 1 |
| 4 | Endocrinology:fertility hormone in repose显示文摘 | Dias J A | 2005 | Nature2005，433，： | 1 |
| 5 | Rapid silver staining and recover of PCR products separated in polyacrylamide gels显示文摘 | SANGUINETTI C J DIAS N E SIMPSON A J G | 1994 | Bio techniques1994，17，： | 1 |
| 6 | F'olysaccha,'ide isolaled from Agardhiella ram()sissima:Chendcal slru('ture and anti- inflanunation activity 显示文摘 | Batista J A Dias EGN Brito TV | 2014 | Carhohydrate Polymers2014，99，1： | 1 |
| 7 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels 显示文摘 | SANGUINETTI C J DIAS NETO E SIMPSON A J | 1994 | Biotechniques1994，17，5： | 1 |
| 8 | Rapid silverstaining and recover of PCR products separated on polycrylamidegels显示文摘 | SANGUINETTI C J DIAS NETO E SIMPSON A J | 1994 | Biotechniques1994，17，5： | 1 |
| 9 | Bioindication of air pollution effects near a copper smelter in Brazil using mango trees and soil microbiological properties显示文摘 | KLUMPP A HINTEMANN T SANTANA DIA J | 2003 | Environmental Pollution2003，126，： | 1 |
| 10 | 显示文摘 | Silva T F Dias J A C Maciel C G | 2013 | Catal Sci Technol2013，3，： | 1 |
| 11 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels polymerase chain reaction product recover显示文摘 | Sanguinetti C J Dias N E Simpson A J | 1994 | Biotechniques1994，17，5： | 1 |
| 12 | Massive barite deposits in the convergent margin off Peru:implications for fluid circulation within subduction zones显示文摘 | Aquilina L Dia A N Boulegue J | 1997 | Geochimica et Cosmochimica1997，61，21： | 1 |
| 13 | The effectiveness of a home care program for supporting caregivers of persons with dementia in developing countries: a randomised controlled tri- al from Goa, India显示文摘 | Dias A Dewey ME D Souza J | 2008 | Plos ONE2008，3，6： | 1 |
| 14 | Regulation of hepatic lipogenesis by dietary protein energy in juvenile European seabass 显示文摘 | DIAS J ALVAREZM J DIEEZ A | 1998 | Aquaculture1998，161，3： | 1 |
| 15 | Regulation of hepatic lipogenesis by dietary protein/energy in juvenile European seabass (Dicentrarchus labrax ) 显示文摘 | Dias J Alvarez M J Diez A | 1998 | Aquaculture1998，161，14： | 1 |
| 16 | Risk factors associated with sero-positivity to Toxoplasma gondii in captive neotropical felids from Brazil显示文摘 | Ramossilva J C Marvulo M F Dias R A | 2007 | Prey Vet Med2007，78，34： | 1 |
| 17 | Magnesium and its alloys as orthopedic biomaterials: A review显示文摘 | STAIGER M P PIETAK A M HUADMAI J DIAS G | 2006 | Biomaterials2006，27，9： | 1 |
| 18 | Multiohjective genetic algorithms applied to solve optimization problems显示文摘 | Dias'A H F De vasconcelos J A | 2002 | IEEE Transactions on Magnetics2002，38，2： | 1 |
| 19 | Nanosized and re- usable SiO2/ZrO2 catalyst for highly efficient biodiesel production by soybean ktransesterification显示文摘 | Faria E A Marques J S Dias I M | 2009 | Braz Chem Soc2009，20，： | 1 |
| 20 | Immobilization of Fe, Mn and Co tetraphenylporphyrin complexes in MCM-41 and their catalytic activity in cyclohexene oxidation reaction by hydrogen peroxide 显示文摘 | COSTA A A GHESTI G F MACEDO J L BRAGA V S SANTOS M M DIAS J A DIAS S C L | 2008 | J Mol Catal A: Chem2008，282，： | 1 |
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