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26篇 您的检索式:作者名="DEFRES"
    题名 作者 年代 出处 被引量
1Innate and adaptive immune responses toward nanomedicines显示文摘Since the commercialization of the frst liposomes used for drug delivery,Doxil/Caelyx® and Myocet®,tremendous progress has been made in understanding interactions between nanomedicines and biological systems.Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more effciently.While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics,the clinical successes of gene silencing approaches like patisiran lipid complexes(Onpattro®)have paved the way for a variety of therapies beyond cancer.In parallel,the global severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has highlighted the potential of mR NA vaccines to develop immunization strategies at unprecedented speed.To rationally design therapeutic and vaccines,chemists,materials scientists,and drug delivery experts need to better understand how nanotechnologies interact with the immune system.This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions.Iara Maíra de Oliveira Viana Sabrina Roussel Joan Defrêne Eliana Martins Lima Frédéric Barabé Nicolas Bertrand 2021Acta Pharmaceutica Sinica B2021,11,4:5
2Nuclear factor–kappaB: a main regulator of inflammation and cell survival in endometriosis pathophysiology显示文摘Reinaldo González-Ramos Sylvie Defrère Luigi Devoto 2012Fertility and Sterility2012,,3:2
3Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis显示文摘González-Ramos Donnez J Defrère S 2007Mol Hum Reprod2007,13,7:1
4Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis显示文摘González-Ramos R Donnez J Defrère S 2007Mol Hum Reprod2007,13,7:1
5Agents blocking the nuclear factor-kappaB pathway are effective inhibitors of endometriosis in an in vivo experimental model显示文摘González-Ramos R Van Langendonckt A Defrère S 2008Gynecol Obstet Invest2008,65,3:1
6Global land cover classification at lkm resolution using a decision tree classifier显示文摘Han M C Defr R S Town S H 2000International Journal of Remote Sensing2000,21,6:1
7Iron overload en-hances epithelial cell proliferation in endometriotic lesions inducedin a murine model显示文摘Defrère S Van Langendonckt A Vaesen S 2006Hum Reprod2006,21,11:1
8Antiangiogenic and vas- cular-disrupting agents in endometriosis :pitfalls and promises显示文摘Van Langendonckt A Donnez J Defr~re S 2008Mol Hum Reprod2008,14,5:1
9Interactions between protected areas and their surroundings in human-dominated tropical landscapes显示文摘DEFRES R KARANTH K K PAREETH S 0,,12:1
10Endometriomas as a possible cause of reduced ovarian reserve in women with endometriosis显示文摘Michio Kitajima Sylvie Defrère Marie-Madeleine Dolmans Sebastien Colette Jean Squifflet Anne Van Langendonckt Jacques Donnez 2011Fertility and Sterility2011,,3:1
11An investigation of the Peutz-Jeghers g ene (LKB1) in sporadic breast and colon cancers显示文摘 Defres S Goudie DR 2000J Clin Pathol2000,53,10:1
12Endometriomas as a possible cause of reduced ovarian reserve in women with endometriosis显示文摘Michio Kitajima Sylvie Defrère Marie-Madeleine Dolmans Sebastien Colette Jean Squifflet Anne Van Langendonckt Jacques Donnez 2011Fertility and Sterility2011,,3:1
13Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis显示文摘 Donnez J Defrère S 2007Mol Hum Reprod2007,13,3:1
14MRSA as a cause of lung in- fection including airway infection, community-acquired pneumonia and hospital-acquired pneumonia显示文摘Defres S Marwick C Nathwani D 2009European Respiratory Jour- nal2009,34,6:1
15Nuclear factor-kappaB : a main regulator of inflammation and cell survival in erldometriosis pathophysiology 显示文摘Gonzflez-Ramos R Defr~re S Devoto L 2012Fertil Steril2012,98,3:1
16Involve- ment of the nuclear factor-KB pathway in the pathogenesis of endo- metriosis 显示文摘Gonz~tlez-Ramos R Van Langendockt A Defr~re S 2010Fertil Steri12010,94,6:1
17An investigation of the Peatz-Jeghers gene 显示文摘Forster L F Defres S Goudie D R 2000J Clin Pathol2000,3,10:1
18Health risk assessment of dioxin emissions from municipal waste incinerators:the neerlandquarter (Wilrijk,Belgium)显示文摘NOUWEN J CORNELIS C DEFRE R 2001Chemosphere2001,43,:1
19Absence of aromatase proteinand mRNA expression in endometriosis显示文摘Colette S Lousse JC Defrère S 2009Hum Reprod2009,24,9:1
20An investigation of the Peutz-Jeghere gene (LKB1) in sporadic breast and colon cancers显示文摘 Defres S Goudie DR 2000J Clin Pathol2000,53,10:1
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