维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

19篇 您的检索式：作者名="DE HARTOG J"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprineor 6-mercaptopurine intolerant IBD patients显示文摘AIM: To determine the tolerability and safety profile of a low-dose maintenance therapy with 6-TG in azathioprine (AZA) or 6-mercaptopurine (6-MP) intolerant inflammatory bowel disease (IBD) patients over a treatment period of at least 1 year.METHODS: Database analysis.RESULTS: Twenty out of ninety-five (21%) patients discontinued 6-TG (mean dose 24.6 mg; mean 6-TGN level 540 pmol/8×108 RBC) within 1 year. Reasons for discontinuation were GI complaints (31%), malaise (15%)and hepatotoxicity (15%). Hematological events occurred in three patients, one discontinued treatment. In the 6-TG-tolerant group, 9% (7/75) could be classified as hepatotoxicity. An abdominal ultrasound was performed in 54% of patients, one patient had splenomegaly.CONCLUSION: The majority of AZA or 6-MP-intolerant IBD patients (79%) is able to tolerate maintenance treatment with 6-TG (dosages between 0.3 and 0.4 mg/kg per d). 6-TG may still be considered as an escape maintenance immunosuppressant in this difficult to treat group of patients, taking into account potential toxicity and efficacy of other alternatives. The recently reported hepatotoxicity is worrisome and 6-TG should therefore be administered only in prospective trials.	Nanne KH de Boer Luc JJ Derijks Lennard PL Gilissen Daniel W Hommes Leopold GJB Engels Sybrand Y de Boer Gijsbertus den Hartog Piet M Hooymans Anja BU M(?)kelburg Barend D Westerveld Anton HJ Naber Chris JJ Mulder Dirk J de Jong	2005	World Journal of Gastroenterology2005，11，35：	4
	2	Effects of ultrafine and fine particulate and gaseous air pollution on cardiac autonomic control in subjects with coronary artery disease:the ULTRA study显示文摘	Timonen KL Vanninen E de Hartog J	2006	J Expo Sci Environ Epidemiol2006，16，4：	1
	3	Primary shoulder arthmplasty versus conservative treatment for comminuted proximal humeral fractures : a systematic literature review 显示文摘	den Hartog D de Haan J Sehep NW	2010	Open Orthop J2010，4，：	1
	4	Primary shoulder arthroplasty versus conservative treatment for comminuted proximal humeral fractures: a systematic literature review显示文摘	Den Hartog D De Haan J Schep NW	2010	Open Orthop J2010，4，：	1
	5	Reactivity of organic matter in aquifer sediments : Geological and geochemical controls 显示文摘	HARTOG NIELS BERGEN P F VAN LEEUW J W DE	2004	Geochimica ct Cosmochimica Acta2004，68，6：	1
	6	Motor ve hicle exhaust and chronic respiratory symptoms in children liv- ing near freeways 显示文摘	VAN VLIET P KNAPE M DE HARTOG J	1997	Environmental Research1997，74，2：	1
	7	The open lung concept:pressure controlled ventilation is as effective as high frequency oscillatory ventilation in improving gas exchange and lung mechanics in surfactant deficient animals显示文摘	Vazquez de Anda G F Hartog A Verbrugge S J C	1999	Intensive Care Med1999，25，：	1
	8	Measuring innovative work behav-iour 显示文摘	DE JONG J DEN HARTOG D	2010	Creativity and Innovation Management2010，19，1：	1
	9	Primary shoulder arthroplasty versus conservative treatment for comminuted proxi- mal humeral fractures: a systematic literature review显示文摘	den Hartog D de Haan J Schep NW	2010	Open Orthop J2010，4，：	1
	10	Do the health benefits of cycling out weigh the risks?显示文摘	Johan DE Hartog J Boogaard H	2010	Environ Health Perspect2010，118，8：	1
	11	Particulate air pollution and risk ofST-segment depression during repeated submaximal exer-cise tests among subjects with coronary heart disease:theExposure and Risk Assessment for Fine and Ultrafine Parti-cles in Ambient Air(ULTRA)study显示文摘	Pekkanen J Peters A Hoek G Tiittanen P BrunekreefB de Hartog J	2002	Circulation2002，106，8：	1
	12	Primary shoulder ar-throplasty versus conservative treatment for comminuted proxi-mal humeral fractures:a systematic literature review显示文摘	den Hartog D de Haan J Schep NW	2010	Open Or-thop J2010，4，：	1
	13	Re- activity of organic matter in aquifer sediments: geological and ge- ochemical controls 显示文摘	HARTOG N VAN BERGEN P F DE LEEUW J W	2004	Geochimica et Cosmochimica Acta2004，68，6：	1
	14	Reactivity of organic matter in aquifer sediments: geological and geochemical controls显示文摘	Hartog N Van Bergen P F De Leeuw J W	2004	Geochim et cosmochim Acta2004，68，6：	1
	15	Effects of fine and ultrafine particles On cardiorespiratory symptoms in elderly subjects with coronary heart disease:the ULTRA study显示文摘	De HARTOG J J HOEK G PETERS A	2003	American Journal of Epidemiology2003，157，7：	1
	16	Primary shoulder arthroplasty versus conservative treatment for comminuted proxi- mal humeral fractures :a systematic literature review 显示文摘	den Hartog D de Haan J Schep NW	2010	Open Or- thop J2010，，：	1
	17	Effects of fine and ultrafine particles on cardiorespiratory symptoms in elderly subjects with coronary heart disease: the ULTRA study显示文摘	de HARTOG J J HOEK G PETERS A	2003	Am J Epidemiol2003，157，：	1
	18	Effects of fine and ultrafme particles on cardiorespiratory symptoms in elderly subjects with coronary heart disease -- The ULTRA study显示文摘	de Hartog J Hoek G Peters A	2003	Am J Epidemiol2003，157，7：	1
	19	Primary shoulder arthroplasty versus conservative treatment for comminuted proximal humeral fractures: a systematic literature review显示文摘	den Hartog D de Haan J Schep NW	2010	Open Orthop J2010，17，4：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费