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| 1 | 24h动态血压监测预测和评估经皮经导管射频消融去肾交感神经术的降压作用显示文摘经皮经导管射频消融去肾交感神经术治疗难治性高血压(renal denervation for resistant hypertension,DENERHTN)临床试验显示,明确诊断的难治性高血压患者经英国指南推荐的标准化阶梯降压治疗(standardized stepped-care antihypertensive treatment,SSAHT)加上使用Symplicity导管的经皮经导管射频消融去肾交感神经术(renal denervation,RDN)。 | Gosse P Cremer A Pereira H Bobrie G Chatellier G Chamontin B Courand P Delsart P Denolle T Dourmap C 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，4： | 6 |
| 2 | Metabolic syndrome and colorectal neoplasms:An ominous association显示文摘AIM:To evaluate the association of metabolic syndrome(MS) and colorectal cancer and adenomas in a Western country,where the incidence of MS is over 27%.METHODS:This was a prospective study between March 2013 and March 2014.MS was diagnosed according to the National Cholesterol Education ProgramATP III.Demographic characteristics,anthropometric measurements,metabolic risk factors,and colonoscopic pathologic findings were assessed in patients with MS(group 1) who underwent routine colonoscopy at our department.This data was compared with consecutive patients without metabolic syndrome(group 2),with no differences regarding sex and age.Patients with incomplete colonoscopy,family history,or past history of colorectal neoplasm were excluded.Informed consent was obtained and the ethics committee approved this study.Statistical analysis was performed using Student's t-test and χ2 test,with a P value ≤ 0.05 being considered statistically significant.RESULTS:Of 258 patients,129 had MS;51% males;mean-age 67.1 years(50-87).Among the MS group,94% had high blood pressure,91% had increased waist circumference,60% had diabetes,55% had low high-density lipoprotein cholesterol level,50% had increased triglyceride level,and 54% were obese [body mass index(BMI) 30 kg/m2].51% presented 4 criteria of MS.MS was associated with increased prevalence of adenomas(43% vs 25%,P = 0.004) and colorectal cancer(13% vs 5%,P = 0.027),compared with patients without MS.MS was also positively associated with multiple(≥ 3) adenomas(35% vs 9%,P = 0.024) and sessile adenomas(69% vs 53%,P = 0.05).No difference existed between location(P = 0.086),grade of dysplasia(P = 0.196),or size(P= 0.841) of adenomas.In addition,no difference was found between BMI(P = 0.078),smoking(P = 0.146),alcohol consumption(P = 0.231),and the presence of adenomas.CONCLUSION:MS is positively associated with adenomas and colorectal cancer.However,there is not enough information in western European countries to justify screening in patients with MS.To our knowledge,no previous study has evaluated this association in Portuguese patients. | Daniel Trabulo Suzane Ribeiro Cláudio Martins Cristina Teixeira Cláudia Cardoso Jo?o Mangualde Ricardo Freire élia Gamito Ana L Alves Fátima Augusto Ana P Oliveira Isabelle Cremers | 2015 | World Journal of Gastroenterology2015，21，17： | 5 |
| 3 | Appropriateness of outpatient gastrointestinal endoscopy in a non-academic hospital显示文摘AIM:To assess the appropriate use and the diagnostic yield of upper gastrointestinal endoscopy and colonoscopy in this subgroup of patients.METHODS:In total,789 consecutive outpatients referred for gastrointestinal(GI) endoscopy [381 for esophagogastroduodenoscopy(EGD) and 408 for colonoscopy] were prospectively enrolled in the study.The American Society for Gastrointestinal Endoscopy(ASGE) guidelines were used to assess the relationship between appropriateness and the presence of relevant endoscopic f indings.RESULTS:The overall inappropriate rate was 13.3%.The indications for EGD and colonoscopy were,respectively,appropriate in 82.7% and 82.6% of the exams,uncertain in 5.8% and 2.4% and inappropriate in 11.5% and 15%.The diagnostic yield was signif icant higher forEGDs and colonoscopies judged appropriate and uncertain when compared with those considered inappropriate(EGD:36.6% vs 36.4% vs 11.4%,P = 0.004;Colonoscopy:24.3% vs 20.0% vs 3.3%,P = 0.001).Of the 25 malignant lesions detected,all but one was detected in exams judged appropriate or uncertain.CONCLUSION:This study shows a good adherence to ASGE guidelines by the referring physicians and a significant increase of the diagnostic yield in appropriate examinations,namely in detecting neoplastic lesions.It underscores the importance that the appropriateness of the indication assumes in assuring high-quality GI endoscopic procedures. | Joo Mangualde Marie I Cremers Ana M Vieira Ricardo Freire lia Gamito Cristina Lobato Ana L Alves Fátima Augusto Ana P Oliveira | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，10： | 2 |
| 4 | CD24 expression causes the acquisition of multiple cellular properties associ- ated with tumor growth and metastasis 显示文摘 | Baumann P Cremers N Kroese F | 2005 | Cancer Res2005，65，10： | 1 |
| 5 | Rapid detection of human chro- mosome 21 aberration by in situ hybridization显示文摘 | Licher P Cremer T Tang JC | 1988 | Proc Nad Aead Sei USA1988，85，24： | 1 |
| 6 | CD24 Expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis 显示文摘 | Baumann P Cremers N Kroese F | 2005 | Cancer Res2005，65，10： | 1 |
| 7 | Low State Control,High Effort at Work and Schemic Heart Dis- ease 显示文摘 | Siegrist J Peter Junge A Cremer P | 1990 | Prospective Evidence from Blue - collar Man1990，31，10： | 1 |
| 8 | Reforming Our Pension System: Is it a Demographic, Financial or Political Problem? 显示文摘 | Cremer H Pestieau P | 2000 | Europe- an Economic Review2000，44，04： | 1 |
| 9 | 显示文摘 | Riensche E Cremer P | 2000 | Journal of Power Sources2000，86，： | 1 |
| 10 | Design and Characterization of Immobilized Enzymes in Mierofluidle Systems 显示文摘 | Mao H B Yang T L Cremer P S | 2002 | Analytilcal Chemistry2002，74，： | 1 |
| 11 | Neural state and trait bases of mood-incongruent memory formation and retrieval in first-episode major depression显示文摘 | van Wingen GA van Eijndhoven P Cremers HR | 2010 | J Psychiatr Res2010，44，8： | 1 |
| 12 | Piracy prevention and the pricingof information goods显示文摘 | Cremer H Pestieau P | 2009 | Information Economics andPolicy2009，21，1： | 1 |
| 13 | Full extraction of the surplus in Bayesian and dominant strategy auctions显示文摘 | Cremer J Mclean R P | | 0，，： | 1 |
| 14 | CD24 Expression causes the acquisition of multiple cellular properties associateel with tumor growth and metastasis 显示文摘 | Baumann P Cremers N Kroese F | 2005 | Cancer Res2005，65，10： | 1 |
| 15 | Piracy prevention and the pricing of information goods 显示文摘 | Cremer H Pestieau P | 2009 | Information Economics and Policy2009，21，1： | 1 |
| 16 | Social immunity 显示文摘 | Cremer S Armitage SA Schmid - Hempel P | 2007 | Current Biology2007，17，16： | 1 |
| 17 | LISEM:a single-event physically-based hydrological and soil erosion model for drainage basins Ⅰ:theory,input and output显示文摘 | De Roo A P J Offermans R J E Cremers D T | 1996 | Hydrological Processes1996，，10： | 1 |
| 18 | The Double Dividend of Postponing Retire- rnent显示文摘 | Cremer H Pestieau P | | 0，，10： | 1 |
| 19 | Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries显示文摘 | Lichter P Cremer T Borden J | 1988 | Hum Genet1988，80，3： | 1 |
| 20 | Prognostic value of the extent of left ventricular hypertrophy and its evolution in the hy- pertensive patient 显示文摘 | Gosse P Cremer A Vircoulon M | 2012 | J Hypertens2012，30，12： | 1 |
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