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	题名	作者	年代	出处	被引量
1	Identification of patients at-risk for Lynch syndrome in a hospital-based colorectal surgery clinic显示文摘AIM:To determine the prevalence of a family history suggestive of Lynch syndrome (LS) among patients with colorectal cancer (CRC) followed in a coloproctology outpatient clinic in Southern Brazil.METHODS:A consecutive sample of patients with CRC were interviewed regarding personal and family histories of cancer.Clinical data and pathology features of the tumor were obtained from chart review.RESULTS:Of the 212 CRC patients recruited,61 (29%) reported a family history of CRC,45 (21.2%) were diagnosed under age 50 years and 11 (5.2%) had more than one primary CRC.Family histories consistent with Amsterdam and revised Bethesda criteria for LS were identified in 22 (10.4%) and 100 (47.2%) patients,respectively.Twenty percent of the colorectal tumors had features of the high microsatellite instability phenotype,which was associated with younger age at CRC diagnosis and with Bethesda criteria (P < 0.001).Only 5.3% of the patients above age 50 years had been previously submitted for CRC screening and only 4% of patients with suspected LS were referred for genetic risk assessment.CONCLUSION:A significant proportion of patients with CRC were at high risk for LS.Education and training of health care professionals are essential to ensure proper management.	Patrícia Koehler-Santos Patricia Izetti Jamile Abud Carlos Eduardo Pitroski Silvia Liliana Cossio Suzi Alves Camey Cláudio Tarta Daniel C Damin Paulo Carvalho Contu Mario Antonello Rosito Patricia Ashton-Prolla Joāo Carlos Prolla	2011	World Journal of Gastroenterology2011，17，6：	2
2	Adventitious shoots from cotyledons of immature cherry and apricot embryos显示文摘	LANE W D COSSIO F	1986	Canadia Journal of Plant Science1986，66，：	1
3	Enuresis显示文摘	Cossio SE		0，，02：	1
4	Oxidation of alcohols using bis (trichloromethyl) carbonate as activator of dimethyl sulfoxide显示文摘	Palomo C Cossio F P Ontoria J M		0，，20：	1
5	Synthesis of pyrazolo pyridines by cycloaddition reactions under microwave irradiation显示文摘	DIAZ-ORTIZ A CARRILLO J R COSSIO F P	2000	Tetrahedron2000，56，11：	1
6	Prevalence of intestinal metaplasia of the gastric cardia and its relation with Helieobacter pylori strains cagA and vacA显示文摘	Abdo - Francis JM Sobrino - Cossio S Berual - Sahagun F	2010	Cir Cir2010，78，4：	1
7	Strategies of the Poorest in Local Water Conflict and Cooperation-Evidence from Vietnam,Bolivia and Zambia显示文摘	Funder M R Bustamante V Cossio P T M Huong B van Koppen C Mweemba I Nyambe L T T Phuong T Skielboe		0，，01：	1
8	Does the firm's market orientation behavior influence innova- tion:s success显示文摘	VEGA VAZQUEZ M COSSIO SILVA F MARTIN RUIZ D	2012	Management Decision2012，50，8：	1
9	Ameloblastic carcinoma of the maxilla:a report of 3 cases显示文摘	Hernandez Guisado JM Fernandez Machin P	1998	J Craniomaxillofac Surg1998，26，：	1
10	Behavior and strength in shear of beams and beams without web reinforcement 显示文摘	Diazde Cossio R	1960	ACI structural journal1960，56，8：	1
11	Existence of solutions for an asymptotically linear diriehlet problem via lazer solimini results accepted manuscript显示文摘	Jorge Cossio Sigifredo Herron Carlos Velet	2008	Nonlinear Analysis2008，，：	1
12	Spermatocytes and round spermatids of rat testis: protein patterns显示文摘	Sanchez JC Golaz O	1995	Electrophoresis1995，16，7：	1
13	Paediatric radial neck fractures: One-step percutaneous reduction and fixation显示文摘	Cossio A Cazzaniga C Gridavilla G	2014	Injury2014，45，6：	1
14	Predicting Topographic and Bathymetric Measurement Performance for Low-SNR Airborne LiDAR显示文摘	Cossio T Slatton K C Carter W	2009	IEEE Transactions on Geoscience and Remote Sensing2009，47，7：	1
15	Adventitious shoots from cotyledons of immature cherry and apricot embryoes显示文摘	Lane W D Cossio F	1986	Canadian Journal of Plant Science1986，66，：	1
16	Tattooing and piercing in teenagers 显示文摘	Perez-Cotapos ML Cossio ML	2006	Rev Med Chil2006，134，10：	1
17	Intra- alveolar chlorhexidinegel for the prevention of dry socket in mandibular third molar surgery a pilot study 显示文摘	Tortes Lagares D Infante Cossio Gutierrez Perez	2006	Med Oral Patol Oral Cir Bucal2006，11，2：	1
18	Behavior and strength in shear of beams and frames without web reinforcement 显示文摘	De Cossio R D Siess C P	1960	ACI Structural Journal1960，56，2：	1
19	How do different indices of obesity correlate with cardiometabolic disease risk factors in multiethnic youths? 显示文摘	Cossio S Messiah SE Garibay-Nieto N	2009	Endocr Pract2009，15，5：	1
20	β-adrenergic effect of antibodies from chagasic patients and normal human lymphocytes on isolated rat a tria显示文摘	Diez C Cossio PM	1982	Clin Exp Immunol,1982，50，：	1

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