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| 1 | Nutritional status and nutritional therapy in inflammatory bowel diseases显示文摘Underweight and specific nutrient deficiencies are frequent in adult patients with inflammatory bowel disease(IBD).In addition,a significant number of children with IBD,especially Crohn's disease(CD) have impaired linear growth.Nutrition has an important role in the management of IBD.In adults with CD,enteral nutrition(EN) is effective in inducing clinical remission of IBD,although it is less efficient than corticosteroids.Exclusive EN is an established primary therapy for pediatric CD.Limited data suggests that EN is as efficient as corticosteroids for induction of remission.Additional advantages of nutritional therapy are control of inflammation,mucosal healing,positive benefits to growth and overall nutritional status with minimal adverse effects.The available evidence suggests that supplementary EN may be effective also for maintenance of remission in CD.More studies are needed to confirm these findings.However,EN supplementation could be considered as an alternative or as an adjunct to maintenance drug therapy in CD.EN does not have a primary therapeutic role in ulcerative colitis.Specific compositions of enteral dietselemental diets or diets containing specific components-were not shown to have any advantage over standard polymeric diets and their place in the treatment of CD or UC need further evaluation.Recent theories suggest that diet may be implicated in the etiology of IBD,however there are no proven dietary approaches to reduce the risk of developing IBD. | Corina Hartman Rami Eliakim Raanan Shamir | 2009 | World Journal of Gastroenterology2009，15，21： | 44 |
| 2 | 儿科肠外营养指南(2016版)推荐意见节译显示文摘儿科肠外营养指南英文完整版共分为14篇,刊登在2018年Clinical Nutrition 。除方法篇外,每篇均给出推荐意见列表。在此,我们将方法篇有关证据级别、推荐等级、推荐形式的相关说明以及其余13篇的推荐建议整理成中文版,供国内儿科医护人员参考学习。 | 欧洲儿科胃肠肝病与营养学会 欧洲临床营养与代谢学会 欧洲儿科研究学会 中华医学会肠外肠内营养学分会 Walter Mihatsch K.Joosten J.B.van'Goudoever Alexandre Lapillonne D.Mesotten F.Joehum M.Domellof J.Bronsky S.Kolacek I.Hojsak Susan Hill Arich Riskin Corina Hartman 颜伟慧(译) 吴江(译) 王莹(译) 蔡威(译) | 2018 | 中华儿科杂志2018，56，12： | 18 |
| 3 | COPPER AMINE OXIDASE1 (CuAO1) of Arabidopsis thaliana Contributes to Abscisic Acid- and Polyamine-lnduced Nitric Oxide Biosynthesis and Abscisic Acid Signal Transduction显示文摘Polyamines (PA ) , polyamine oxidases,铜胺 oxidases,和氮的氧化物(没有) 在植物在生理学和压力回答起重要作用。由于由 polyamine oxidases 和铜胺 oxidases 的 PA 的分解代谢的生合成都可以不解释部分地调停 PA 的回答。铜胺 oxidase 基因的参与,铜胺 OXIDASE1 (CuAO1 ) ,用大美人 cuao1-1 和 cuao1-2 在压力回答为它的角色 Arabidopsis 被测试。导致 PA 、导致骆驼毛的织物萤光计和荧光显微镜学调查的生产都没证明 cuao1-1 和 cuao1-2 在没有生产被损害,在 PA 建议 CuAO1 的功能并且调停骆驼毛的织物没有生产。而且,我们在蛋白质 S-nitrosylation 发现了 PA 依赖的增加。PA 和骆驼毛的织物的增加也导致了 H2O2 增加。cuao1-1 和 cuao1-2 作为与相比在萌芽,幼苗建立,和根生长抑制期间显示出更少的敏感到外长的骆驼毛的织物补充野类型。响应骆驼毛的织物处理,压力应答的基因 RD29A 和 ADH1 的表示层次在大美人是显著地更低的。这些观察作为骆驼毛的织物感觉迟钝的异种描绘 cuao1-1 和 cuao1-2。一起拿,我们的调查结果扩大 ABA 信号 transduction 网络作为一个潜在的贡献者包括 CuAO1 到没由骆驼毛的织物提高生产。 | Rinukshi Wimalasekera Corina Villar Tahmina Begum Giinther F. E. Scherer | 2011 | Molecular Plant2011，4，4： | 12 |
| 4 | MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines显示文摘AIM:To investigate expression of microRNA(miRNA)and potential targets in chemotherapy resistant esoph-ageal cancer cell lines.METHODS:An in-vitro model of acquired chemotherapy resistance in esophageal adeno-(EAC)and squamous cell carcinoma(ESCC)cells was used,and microRNA expression profiles for cisplatin or 5-fluorouracil(5-FU)resistant variants vs chemotherapy sensitive controls were compared using microarray and quantitative real-time polymerase chain reaction(PCR).The expression of chemotherapy-relevant genes potentially targeted by the dysregulated microRNAs in the chemotherapy resistant variants was also evaluated.RESULTS:Chemotherapy resistant sublines were found to have specific miRNA signatures,and these miRNA signatures were different for the cisplatin vs 5-FU resistant cells from the same tumor cell line,and also for EAC vs ESCC cells with resistance to the same specific chemotherapy agent.Amongst others,miR-27b-3p,miR-193b-3p,miR-192-5p,miR-378 a-3p,miR-125a-5p and miR-18a-3p were dysregulated,consistent with negative posttranscriptional control of KRAS,TYMS,ABCC3,CBL-B and ERBB2 expression via these miRNAs.CONCLUSION:The current study supports the hypothesis that microRNA expression has an impact on chemotherapy resistance in esophageal cancer. | Richard Hummel Corina Sie David I Watson Tingting Wang Alfiya Ansar Michael Z Michael Mark Van der Hoek Joerg Haier Damian J Hussey | 2014 | World Journal of Gastroenterology2014，20，40： | 8 |
| 5 | Control of PHERES1 Imprinting in Arabidopsis by Direct Tandem Repeats显示文摘印的 Genomic 是引起依赖于 parent-of-origin 的特定的基因的 monoallelic 表示的 epigenetic 现象。Arabidopsis 基因 PHERES1 印要求 FERTILIZATION 独立种子(FIS ) Polycomb 组建筑群以及包含一个双人脚踏车三元组重复序列的一个远侧地定位的 methylated 区域的功能。在这研究,我们调查了靠近的 PHERES1 相当或相同的事物 PHERES2 的规定。我们发现 PHERES2 也是 FIS Polycomb 组建筑群的直接目标基因,,但是,与 PHERES1 相对照, PHERES2 同等地从母亲、父亲的等位基因被表示。因此, PHERES2 没被印的 genomic 调整,与在 PHERES2 的双人脚踏车重复的缺乏相关。从 PHERES1 地点消除双人脚踏车重复废除印的 PHERES1,证明双人脚踏车重复为印的 PHERES1 是必要的。一起拿这些结果,我们最近复制的基因 PHERES1 和 PHERES2 两个都是 FIS Polycomb 的目标基因的学习表演组织建筑群但是仅仅 PHERES1 被印的 genomic 调整,它是可能的在 PHERES1 地点的最近由重复序列的存在引起了。 | Corina Belle R. Villar Aleksandra Erilova Grigory Makarevich Raphael Trosch Claudia Kohler | 2009 | Molecular Plant2009，2，4： | 6 |
| 6 | 为胃的倒空和活动性评估的电的 bioimpedance 和另外的技术显示文摘 The aim of this article is to identify non-invasive, inexpensive, highly sensitive and accurate techniques for evaluating and diagnosing gastric diseases. In the case of the stomach, there are highly sensitive and specific methods for assessing gastric motility and emptying (GME). However, these methods are invasive, expensive and/or not technically feasible for all clinicians and patients. We present a summary of the most relevant international information on non-invasive methods and techniques for clinically evaluating GME. We particularly emphasize the potential of gastric electrical bioimpedance (EBI). EBI was initially used mainly in gastric emptying studies and was essentially abandoned in favor of techniques such as electrogastrography and the gold standard, scintigraphy. The current research evaluating the utility of gastric EBI either combines this technique with other frequently used techniques or uses new methods for gastric EBI signal analysis. In this context, we discuss our results and those of other researchers who have worked with gastric EBI. In this review article, we present the following topics: (1) a description of the oldest methods and procedures for evaluating GME; (2) an explanation of the methods currently used to evaluate gastric activity; and (3) a perspective on the newest trends and techniques in clinical and research GME methods. We conclude that gastric EBI is a highly effective non-invasive, easy to use and inexpensive technique for assessing GME. | María Raquel Huerta-Franco Miguel Vargas-Luna Juana Berenice Montes-Frausto Corina Flores-Hernández Ismael Morales-Mata | 2012 | World Journal of Gastrointestinal Pathophysiology2012，3，1： | 5 |
| 7 | Technical tailoring of pancreaticoduodenectomy in patients with hepatic artery anatomic variants显示文摘BACKGROUND:Pancreaticoduodenectomy is the treatment of choice for periampullary and pancreatic head tumors.In case of hepatic artery abnormalities,early pancreatic transection during pancreaticoduodenectomy may prove inappropriate Early retroportal lamina dissection improves exposure of the superior mesenteric vessels and anatomic variants of the hepatic artery,where safeguarding is mandatory.METHOD:We describe our early retroportal lamina approach in patients with anatomic variants of the hepatic artery before pancreatic transection.RESULTS:This approach was used during 42 pancreatico duodenectomies with a hepatic artery anatomic variant which was spared in 40 patients.Arterial reconstruction was performed in 2 patients.Five patients with a hepatic artery variant and adenocarcinoma involving the portomesenteric junction required venous resection and reconstruction.CONCLUSIONS:Early retroportal lamina dissection during pancreaticoduodenectomy in patients with hepatic artery anatomic variants enables easier exposure,avoiding injuries that might compromise the liver arterial supply.When the portomesenteric vein is involved,this approach facilitates en bloc 'no touch' venous resection and reconstruction. | Cristian Lupascu Dan Andronic Corina Ursulescu Ciprian Vasiluta Nutu Vlad | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 3 |
| 8 | 胃肠的道上的职业应力的效果显示文摘 The aim of this review is to provide a general overview of the relationship between occupational stress and gastrointestinal alterations. The International Labour Organization suggests occupational health includes psychological aspects to achieve mental well-being. However, the definition of health risks for an occupation includes biological, chemical, physical and ergonomic factors but does not address psychological stress or other affective disorders. Nevertheless, multiple investigations have studied occupational stress and its physiological consequences, focusing on specific risk groups and occupations considered stressful. Among the physiological effects of stress, gastrointestinal tract(GIT) alterations are highly prevalent. The relationship between occupational stress and GIT diseases is evident in everyday clinical practice; however, the usual strategy is to attack the effects but not the root of the problem. That is, in clinics, occupational stress is recognized as a source of GIT problems, but employers do not ascribe it enough importance as a risk factor, in general, and for gastrointestinal health, in particular. The identification, stratification, measurement and evaluation of stress and its associated corrective strategies, particularly for occupational stress, are important topics to address in the near future to establish the basis for considering stress as an important risk factor in occupational health. | María-Raquel Huerta-Franco Miguel Vargas-Luna Paola Tienda Isabel Delgadillo-Holtfort Marco Balleza-Ordaz Corina Flores-Hernandez | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，4： | 3 |
| 9 | High resolution, binder-free investigation of the intrinsic activity of immobilized NiFe LDH nanoparticles on etched carbon nanoelectrodes显示文摘The determination of the intrinsic properties of nanomaterials is essentialfor their optimization as electrocatalysts, however it poses great challengesfrom the standpoint of analytical tools and methods. Herein, we report anovel methodology that allows for a binder-free investigation of electrocatalystnanoparficles. The potential-assisted immobilization of a non-noble metalcatalyst, i.e., nickel-iron layered double hydroxide (NiFe LDH) nanoparticles, wasemployed to directly attach small nanoparticle ensembles from a suspensionto the surface of etched carbon nanoelectrodes. The dimensions of this type ofelectrodes allowed for the immobilization of the catalyst material below thepicogram scale and resulted in a high resolution towards the faradaic currentresponse. In addition the effect of the electrochemical aging on the intrinsic activityof the catalyst was investigated in alkaline media by means of continuous cyclicvoltammetry. A change in the material properties could be observed, which wasaccompanied by a substantial decrease in its intrinsic activity. | Patrick Wilde Stefan Barwe Corina Andronescu Wolfgang Schuhmann Edgar Ventosa | 2018 | Nano Research2018，11，11： | 3 |
| 10 | Cardiovascular disease risk factor profiles in children with celiac disease on gluten-free diets显示文摘AIM:To describe the cardiovascular disease(CVD)risk factors in a population of children with celiac disease(CD)on a gluten-free diet(GFD).METHODS:This cross-sectional multicenter study was performed at Schneider Children’s Medical Center of Israel(Petach Tiqva,Israel),and San Paolo Hospital(Milan,Italy).We enrolled 114 CD children in serologic remission,who were on a GFD for at least one year.At enrollment,anthropometric measurements,blood lipids and glucose were assessed,and compared to values at diagnosis.The homeostasis model assessment-estimated insulin resistance was calculated as a measure of insulin resistance.RESULTS:Three or more concomitant CVD risk factors[body mass index,waist circumference,low density lipoprotein(LDL)cholesterol,triglycerides,blood pressure and insulin resistance]were identified in 14%of CD subjects on a GFD.The most common CVD risk factors were high fasting triglycerides(34.8%),elevated blood pressure(29.4%),and high concentrations of calculated LDL cholesterol(24.1%).On a GFD,four children(3.5%)had insulin resistance.Fasting insulin and HOMA-IR were significantly higher in the Italian cohort compared to the Israeli cohort(P<0.001).Children on a GFD had an increased prevalence of borderline LDL cholesterol(24%)when compared to values(10%)at diagnosis(P=0.090).Trends towards increases in overweight(from 8.8%to 11.5%)and obesity(from 5.3%to 8.8%)were seen on a GFD.CONCLUSION:This report of insulin resistance and CVD risk factors in celiac children highlights the importance of CVD screening,and the need for dietary counseling targeting CVD prevention. | Lorenzo Norsa Raanan Shamir Noam Zevit Elvira Verduci Corina Hartman Diana Ghisleni Enrica Riva Marcello Giovannini | 2013 | World Journal of Gastroenterology2013，19，34： | 3 |
| 11 | Pegylated-interferon alpha 2a treatment for chronic hepatitis C in patients on chronic haemodialysis显示文摘瞄准:评估反应到 pegylated 干扰素高山哈在长期的血液透析上的长期的丙肝病人的 2a。方法:有长期的 C 肝炎的十个病人在这研究被注册。所有为超过 6 瞬间,积极 antiHCV 抗体和积极 PCR HCV-RNA 增加了 aminotransferases。我们管理了木钉干扰素高山哈 2a 为 48 wk 的 180 microg/wk。在治疗的 12 wk 以后,我们评估了生物化学、早的 virological 反应(EVR ) 。在治疗的结束,我们在我们评估了的治疗的结束以后评估了生物化学的反应和 24 wk 持续 virological 反应(SVR ) 。我们在治疗期间监视了副作用。结果:二个病人在治疗的开始的 12 wk 放弃了并且 2 在治疗的开始的 12 wk 以后。在治疗的 12 wk 以后, 7 从 8 个病人有生物化学的反应和 EVR, 1 有生物化学的反应但是坚持的病毒血。我们不得不在 2 种情况中把 pegylated 干扰素的剂量归结为 135 mug/wk。三(50%) 从 6,病人们在治疗的结束以后有 SVR 24 wk。Intention-to-treat 分析证明 3 从 10 个病人(30%) 有 SVR。副作用发生在大多数病人(像流感的症候群,血小板减少或 leucopoenia ) ,但是他们没强加治疗的中止。结论:在有木钉干扰素高山的治疗的 12 wk 以后哈在有长期的 C 肝炎的长期的血液透析上的病人的 2a (40 ku ) , EVR 在 87.5% 被获得(7/8 ) 盒子。SVR 在完成了治疗的 48 wk 的 50% 盒子(3/6 病人) 中被完成。 | Ioan Sporea Alina Popescu Roxana ■irli Ovidiu Golea CameliaTotolici Mirela Dǎnilǎ Corina Vernic | 2006 | World Journal of Gastroenterology2006，12，26： | 2 |
| 12 | Fluoropyrimidine-induced cardiotoxicity显示文摘Cardio-oncology is a discipline based on early screening,monitoring,and treating chemotherapy-induced cardiotoxicity.There are many chemotherapeutics known for their cardiac toxic effects,including fluoropyrimidines.Fluoropyrimidine represents the cornerstone of many types of cancer and each year almost two million cancer patients undergo this treatment.Fluoropyrimidine-induced cardiotoxicity can be manifested in several forms,from angina pectoris to sudden death.This paper is a review of how the cardiotoxicity of fluoropyrimidines is presented,the mechanisms of its occurrence,its diagnosis,and management. | Andrada Larisa Deac Claudia Cristina Burz Ioana Corina Bocsan Anca Dana Buzoianu | 2020 | World Journal of Clinical Oncology2020，11，12： | 2 |
| 13 | 甘油氧化的光谱电化学傅里叶变换衰减全反射谱红外光谱薄膜流动池中硼酸镍层厚度的优化显示文摘在碱性甘油电氧化反应中,利用电化学傅里叶变换衰减全反射谱红外光谱法,研究了薄膜流动池中滴注硼酸镍催化剂负载量对玻碳电极性能的影响.连续操作的径向流动池包括一个位于内反射元件上方50μm的钻孔电极,可实现红外光谱分析.这是在确定条件下对电催化剂进行简便和可重复筛选的一个适合的方法,同时还提供了对复杂反应(如甘油氧化)产物选择性的检测.通过对泵送电解液进行更耗时的定量高效液相色谱分析,结果表明,衰减全反射红外光谱法可快速鉴定产物.在层流条件下,水中使用0.1 M甘油和1 M KOH,流速为5μL min^(-1)时,甘油转化率较高.转化率和选择性取决于催化剂的负载量,负载量又决定了催化剂层的厚度和粗糙度.由于在更粗糙的膜中停留时间更长有利于再吸附和C-C键断裂,因此当负载量最高达210μg cm^(-2)时,甘油转化率为73%且甲酸选择性接近80%.当最低负载量为13μg cm^(-2)时,甘油转化率达到63%,甲酸选择性降至60%,相应地,C_(2)物种(如乙醇酸盐)选择性较高,为8%.因此,只有催化剂负载量较低时才能形成几微米厚度范围内的薄膜,此时才适合进行优质催化剂的筛选. | Steffen Cychy Sebastian Lechler Zijian Huang Michael Braun Ann Cathrin Brix Peter Blümler Corina Andronescu Friederike Schmid Wolfgang Schuhmann Martin Muhler | 2021 | Chinese Journal of Catalysis2021，42，12： | 2 |
| 14 | Unsteady flow of viscoelastic fluid between two cylinders using fractional Maxwell model显示文摘The unsteady flow of an incompressible fractional Maxwell fluid between two infinite coaxial cylinders is studied by means of integral transforms.The motion of the fluid is due to the inner cylinder that applies a time dependent torsional shear to the fluid.The exact solutions for velocity and shear stress are presented in series form in terms of some generalized functions.They can easily be particularized to give similar solutions for Maxwell and Newtonian fluids.Finally,the influence of pertinent parameters on the fluid motion,as well as a comparison between models,is highlighted by graphical illustrations. | Muhammad Jamil Constantin Fetecau Corina Fetecau | 2012 | Acta Mechanica Sinica2012，28，2： | 2 |
| 15 | NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn’s disease显示文摘 | Batia Weiss Raanan Shamir Yoram Bujanover Mati Waterman Corina Hartman Akiva Fradkin Drora Berkowitz Ilana Weintraub Ram Eliakim Amir Karban | 2004 | The Journal of Pediatrics2004，，2： | 2 |
| 16 | The function of Stat3 in tumor cells and their microenvironment显示文摘 | Bernd Groner Peter Lucks Corina Borghouts | 2008 | Seminars in Cell and Developmental Biology2008，，4： | 2 |
| 17 | Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: Which anatomic structures are affected and can they be spared by IMRT?显示文摘 | Avraham Eisbruch Marco Schwartz Coen Rasch Karen Vineberg Eugene Damen Corina J. Van As Robin Marsh Frank A. Pameijer Alfons J.M. Balm | 2004 | International Journal of Radiation Oncology Biology Physics2004，，5： | 1 |
| 18 | Psycholinguistic investigations of phonological structure in ASL显示文摘 | Corina D P Hildebrandt U C | 2002 | Modality and Structure in Signed and Spoken Languages2002，，： | 1 |
| 19 | Pharmacodynamic Interaction between Propofol and Remifentanil Regarding Hypnosis, Tolerance of Laryngoscopy, Bispectral Index, and Electroencephalographic Approximate Entropy显示文摘 | Thomas W. Bouillon J?rgen Bruhn Lucian Radulescu Corina Andresen Thomas J. Shafer Carol Cohane Steven L. Shafer | 2004 | Anesthesiology2004，，6： | 1 |
| 20 | Effect of Cracking on Water and Chloride Permeability of Concrete显示文摘 | Corina Maria Aldea Surendra P Shah Member | 1999 | Journal of Materials in Civil Engineering1999，11，3： | 1 |
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