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| 1 | Synthesis of New Substituted 4-Amino-3,5-dinitropyridine Derivatives显示文摘为一些新 4-amino-3,5-dinitropyridine 衍生物的准备的灵巧的合成线路被揭示了。2-chloropyridin-4-amine (1 ) 的硝代作为开始的材料在意外一步舞反应,给 dinitrated 衍生物,由分别地,有钠叠氮化物,钾氟化物,氨,甲胺,和 4-nitroimidazol 的反应给了代替的 4-amino-3,5-dinitropyridine 衍生物的亲核的替换列在后面。同时,它的叠氮化物衍生物经历了戒指闭合变换进 7-amino-6-nitro-[1,2,5 ] oxadiazolo [3,4-b ] pyridine-1-oxide。是意义所有在温和条件下面亲核的替换反应被执行。 | Congming Ma Yongbin Wang Kehui Hou Zuliang Liu Qizheng Yao | 2013 | Chinese Journal of Chemistry2013，31，10： | 4 |
| 2 | Synthesis of 2-Azido-4-nitroimidazole and Its Derivatives for High-Energy Materials显示文摘2-Azido-4-nitroimidazole 和它的衍生物为精力充沛的材料应用程序被综合了。综合混合物被 1H, 13C NMR 光谱学和元素的分析充分描绘。他们中的大多数被单个水晶 X 光检查衍射决定。混合物的计算密度在 1.71 和 1.92 g 牡汹祰慲潺敬 ? 典昊鰬[整之间变化吗? | Kehui Hou Congming Ma Zuliang Liu | 2013 | Chinese Journal of Chemistry2013，31，12： | 2 |
| 3 | Molecular Epidemiology of Klebsiella pneumoniae from Clinical Bovine Mastitis in Northern Area of China,2018–2019显示文摘Klebsiella pneumoniae(K.pneumonia,KpⅠ)is a predominate inducement of bovine mastitis,which is associated with high mortality and milk yield reduction.However,data is lacking on the molecular characteristics of bovine K.pneumoniae,limiting the risk assessment of its transmission through the food chain.Herein,we investigated the prevalence of K.pneumoniae in 6301 clinical mastitis(CM)milk samples from dairy cattle in northern area of China.In total,183 K.pneumoniae isolates were recovered,with detection rates of 3.0% and 2.8% in 2018 and 2019,respectively.Like human clinical K.pneumoniae,all CM K.pneumoniae isolates belonged to one of three phylogroups:KpⅠ(n=143),Klebsiella.quasipneumoniae subsp.similipneumoniae(KpⅡ-B)(n=37),and Klebsiella variicola(KpⅢ)(n=3).We detected the extendedspectrum β-lactamase-encoding genes bla_(SHV-2a),blac_(CTX-M-14),and bla_(CTX-M-15),as well as clpC,lpfA,lacI,lacZ,lacY,and the fecABDEIR operon in the KpⅠ isolates,which may contribute to their pathogenicity and host adaptability in cows.The high prevalence of KpⅠ in dairy farms may be problematic,as it showed relatively higher rates of antibiotic resistance and virulence gene carriage than the KpⅡ-B and KpⅢ isolates.Furthermore,we observed distinct differences in population structure between CM-and human infection-associated KpⅠ isolates,with the genes associated with invasive infection in humans rarely being observed in bovine isolates,indicating that few CM-associated K.pneumoniae isolates pose a threat to human health.Nevertheless,bovine KpⅡ-B isolates shared a high level of nucleotide sequence identity with isolates from human infections and frequently carried the nitrogen-fixation gene nif,suggesting an association between KpⅡ-B isolates from cattle and humans,and plant-derived bacteria. | Shikai Song Wenjuan He Dawei Yang Manar Benmouffok Yao Wang Jiyun Li Chengtao Sun Xiangbin Song Shizhen Ma Chang Cai Shuangyang Ding Congming Wu Zhangqi Shen Yang Wang | 2022 | Engineering2022，8，3： | 1 |
| 4 | Multi responsive methylcellulose/Fe-alginate-g-PVA/PVA/Fe3O4 microgels for immobilizing enzyme 显示文摘 | Xiao Congming Ma Peipei Geng Nannan | 2011 | Polymers for Advanced Technologies2011，22，12： | 1 |
| 5 | Regularity of solutions for an integral system of Wolff type显示文摘 | Chao Ma Wenxiong Chen Congming Li | 2010 | Advances in Mathematics2010，，3： | 1 |
| 6 | Tracking Campylobacter contamination along a broiler chicken production chain from the farm level to retail in China显示文摘 | Licai Ma Yang Wang Jianzhong Shen Qijing Zhang Congming Wu | 2014 | International Journal of Food Microbiology2014，，： | 1 |
| 7 | Regularity of solutions for an integral system of Wolff type显示文摘 | Ma Chao Chen Wenxiong Li Congming | 2011 | Adv Math2011，226，： | 1 |
| 8 | Transmission of Carbapenem Resistance Between Human and Animal NDM-Positive Escherichia coli Strains显示文摘Although carbapenem use is prohibited in animals in China,carbapenem-resistant Escherichia coli(CREC),especially New Delhi metallo-β-lactamase(NDM)-producing strains,are widely prevalent in foodproducing animals.At present,the impact of livestock-associated CREC strains on human populations at the national level is unknown.Here,we conduct a retrospective cross-sectional study to investigate the prevalence of CREC from clinical settings across 22 Chinese provinces or municipalities and analyze anthropogenic factors associated with their presence.We also ascertain the blaNDMand blaKPCabundance among pig and chicken farms and present a detailed genomic framework for CREC of animal and human origin.Overall,631/29799(2.1%)clinical Escherichia coli(E.coli)isolates were identified as CREC.Multivariable analysis revealed that being male,an age below 1,an age between 13 and 18,provinces with greater chicken production,and provinces with higher pig production were associated with higher odds of CREC infection.In general,73.8%(n=45/61)of pig farms and 62.2%(n=28/45)of chicken farms had a blaNDMabundance of 1×10^(-5)to 1×10^(-3)and 1×10^(-3)to 1×10^(-2),respectively.Among all the Chinese NDM-positive E.coli(n=463)available at the National Center for Biotechnology Information(NCBI),the genomic analysis revealed that blaNDM-5and Inc X3 were the predominant carbapenemase gene-plasmid combination,while a highly homogeneous relationship between NDM-positive isolates from humans and animals was demonstrated at the plasmid and core genome levels.All the findings suggest frequent CREC transmission between humans and animals,indicating that further discussions on the use of antibiotics in animals and humans are needed,both in China and across the globe. | Yingbo Shen Fupin Hu Yongqiang Wang Dandan Yin Lu Yang Yiqiang Chen Chunyan Xu Jiyun Li Junyao Jiang Xueyang Wang Yulin Fu Dongyan Shao Dejun Liu Tengfei Ma Chang Cai Zhangqi Shen Shaolin Wang Juan Li Rong Zhang Yuebin Ke Congming Wu Jianzhong Shen Timothy R.Walsh Yang Wang | 2022 | Engineering2022，8，8： | 0 |
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