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| 1 | 血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI. | Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A | 2014 | 中华神经外科疾病研究杂志2014，13，3： | 6 |
| 2 | 门诊烧伤的预防与治疗显示文摘大多数烧伤可由初级保健医生在门诊实施治疗。加强预防可使烧伤发生率明显下降,特别对儿童而言。与其他创伤管理相似,烧伤管理包括初级和次级评估。处理浅度烧伤可采用药液、蜂蜜、芦荟或抗生素软膏局部用药。部分皮层烧伤局部用抗菌药物或吸收性封闭敷料有助于减少疼痛、促进愈合和防止创面干燥。 | Emillia CO Lloyd Blake C Rodgers 周淑新(译) 葛军(译) | 2013 | 中国全科医学2013，16，9： | 3 |
| 3 | 曲马多治疗糖尿病性神经疼痛的双盲随机试验显示文摘目的 :本研究旨在评价曲马多治疗糖尿病性神经痛的有效性和安全性。背景 :糖尿病性神经痛是糖尿病患者的主要症状 ,其治疗和其他的末梢神经病变一样 ,不能令人满意。曲马多是作用于中枢的镇痛剂 ,用于治疗中到重度疼痛。方法 :多中心、门诊病例、随机、双盲、安慰剂做对照、设置平行组的研究 ,包括清洗期 (在此期间停用所有镇痛剂 )和一个为期 42天的双盲治疗期。总共有 1 31名患糖尿病性神经痛的患者按每日 4次接受了曲马多 (n =65)或看上去与曲马多相同的安慰剂胶囊治疗 (n =66)。 42天的治疗结束后或治疗中断后比较曲马多组和安慰剂组平均疼痛强度评分作出主要有效性分析 ;次要有效性分析为疼痛缓解率评分和根据日常活动和睡眠状况作出的对生活质量的评估。结果 :曲马多平均剂量为 2 1 0mg/天 ,治疗糖尿病性神经痛较安慰剂有显著疗效 (P≤ 0 .0 0 1 )。曲马多组患者生理(P =0 .0 2 )和社会功能 (P =0 .0 4 )的评分显著优于安慰剂组。未发现对睡眠有显著治疗作用。曲马多最常见的不良反应是恶心 ,便秘 ,头疼和嗜睡。结论 | Harati Y Gooch C Swenson M Green D Raskin P Donofrio P Cornblath D Sachdeo R Siu CO Kamin M | 2001 | 中国疼痛医学杂志2001，7，1： | 2 |
| 4 | 由磁共振成像评估的主动脉弓脉搏波传导速度是心血管事件的预测因子:多种族动脉粥样硬化研究显示文摘通过磁共振成像评估的主动脉弓脉搏波传导速度(pulse wave velocity,PWV)对心血管病事件的预测价值尚未完全确定。为了评估多种族动脉粥样硬化研究(multi-ethnic study of atherosclerosis,MESA)受试者中主动脉弓PWV与心血管病的关系,Ohyama等纳入3527例MESA受试者[基线时平均年龄为(62±10)岁,47%为男性], | 刘莉 叶鹏 Ohyama Y Ambale-Venkatesh B Noda C Kim JY Tanami Y Teixido-Tura G Chugh AR Redheuil A Liu CY Wu CO Hundley WG Bluemke DA Guallar E Lima JAC | 2017 | 中华高血压杂志2017，25，8： | 2 |
| 5 | Theoretical and experimental characterization of transient electromagnetic fields radiated by electromagnetic fields radiated by electrostatic discharge (ESD) currents显示文摘 | Graziano C Simona Ch Simone Co | 2002 | IEEE Trans on Electromagnetic Compatibility2002，44，1： | 1 |
| 6 | Chronic hepatitis C and type Ⅱ diabetes mellitus: a prospective cross-sectional study显示文摘 | Zein CO Levy C Basu A | 2005 | Am J Gastroenterol2005，100，1： | 1 |
| 7 | Involvement of cholinergic neuronal systems in intravenous cocaine self-administration 显示文摘 | Co C Yin X | 2004 | Neurosci Biobehav Rev2004，27，8： | 1 |
| 8 | Production of biogenic amines in ' Salamini italiani alla cacciatora PDO'显示文摘 | Co(i)sson J D Cerutti C Travaglia F | | 0，，02： | 1 |
| 9 | Transient,recurrent,white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation显示文摘 | Hanemann CO Bergmann C Senderek J | 2003 | Arch Neurol2003，60，4： | 1 |
| 10 | Transient,recurrent,white matter lesions in X-linked Charcot-Marie-Tooth disease with novel connexin 32 mutation显示文摘 | Bergmann C Senderek J | 2003 | Arch Neurol2003，60，： | 1 |
| 11 | Chronic hepatitis C and type Ⅱ diabetes mellitus: a prospective cross-sectional study 显示文摘 | Zein CO Levy C Basu A | 2005 | Am J Gastroenterol2005，100，： | 1 |
| 12 | The Robustness of CAN-Q in Modeling Automated Manufacturing Systems 显示文摘 | Co H C Wysk R A | 1986 | International Journal of production Research1986，，10： | 1 |
| 13 | Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF显示文摘 | Jacob CO Pricop L Putterman C | 2006 | J Immunol2006，177，4： | 1 |
| 14 | Characterization of tumor cell dissemination patterns in preclinical models of cancer metastasis using flow cytometry and laser scanning cytometry显示文摘 | Goodale D Phay C Postenka CO | 2009 | Cytometry A2009，75，4： | 1 |
| 15 | Influence ot' the fire re- tardaotlium polyphosphate, on the thermal degrada- tion of poly(metfa Tlthacrylate)显示文摘 | CO G Grassie N Mcneill I C | 1978 | Journal of Polymer Science1978，16，1： | 1 |
| 16 | Use of RAPD to detect sodium arsenite-induced DNA damage in human lym- phoblastoid cells 显示文摘 | Lee Y Co Yang V C Wang T S | 2007 | Toxicology2007，239，： | 1 |
| 17 | Malignancy is increased in ANCA-associated vasculitis显示文摘 | Pankhurst T Savage CO Gordon C | 2004 | Rheumatology2004，43，： | 1 |
| 18 | Do Patent Rights Regimes Matter? 显示文摘 | CO C C | 2004 | Re- view of International Economics2004，12，3： | 1 |
| 19 | Gas Dispersion Properties:Bubble Surface Area Flux and Gas Holdup显示文摘 | Finch JA Xiao J Hardie C Gomez CO | 2000 | Minerals Engineering2000，，13： | 1 |
| 20 | The effects of environmental regulations on foreign direct investment 显示文摘 | ~List J A Co C Y | 2000 | Journal of Environmental Economics and Management2000，40，： | 1 |
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