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| 1 | Predictive findings forHelicobacter pylori-uninfected, -infected and -eradicated gastric mucosa: Validation study显示文摘AIM:To validate the usefulness of screening endoscopy findings for predictingHelicobacter pylori (H. pylori) infection status. METHODS:H. pylori infection status was determined by histology, serology, and the urea breast test in 77 consecutive patients who underwent upper endoscopy. Based on the findings, patients were categorized as H. pylori -uninfected, -infected, or -eradicated cases. Using six photos of certain sites in the stomach per case, we determined the presence or absence of the following endoscopic findings:regular arrangement of collecting venules (RAC), linear erythema, hemorrhage, fundic gland polyp (FGP), atrophic change, rugal hyperplasia, edema, spotty erythema, exudate, xanthoma, and mottled patchy erythema (MPE). The diagnostic odds ratio (DOR) and inter-observer agreement (Kappa value) for these 11 endoscopic findings used in the determination of H. pylori infection status were calculated. RESULTS:Of the 77 patients [32 men and 45 women; mean age (SD), 39.7 (13.4) years] assessed, 28 were H. pylori uninfected, 28 were infected, and 21 were eradicated. DOR values were significantly high (< 0.05) for the following H. pylori cases:uninfected cases with RAC (11.5), linear erythema (24.5), hemorrhage (4.1), and FGP (34.5); for infected cases with atrophic change (8.67), rugal hyperplasia (15.8), edema (14.2), spotty erythema (11.5), and exudate (3.52); and for eradicated cases with atrophic change (32.4) and MPE (103.0). Kappa values were excellent for FGP (0.93), good for RAC (0.63), hemorrhage (0.79), atrophic change (0.74), and MPE (0.75), moderate for linear erythema (0.51), rugal hyperplasia (0.49), edema (0.58), spotty erythema (0.47), and exudate (0.46), and poor for xanthoma (0.19). CONCLUSION:The endoscopic findings of RAC, hemorrhage, FGP, atrophic change, and MPE will be useful for predicting H. pylori infection status. | Kazuhiro Watanabe Naoyoshi Nagata Ryo Nakashima Etsuko Furuhata Takuro Shimbo Masao Kobayakawa Toshiyuki Sakurai Koh Imbe Ryota Niikura Chizu Yokoi Junichi Akiyama Naomi Uemura | 2013 | World Journal of Gastroenterology2013，19，27： | 17 |
| 2 | Magnifying Narrowband Imaging Is More Accurate Than Conventional White-Light Imaging in Diagnosis of Gastric Mucosal Cancer显示文摘 | Yasumasa Ezoe Manabu Muto Noriya Uedo Hisashi Doyama Kenshi Yao Ichiro Oda Kazuhiro Kaneko Yoshiro Kawahara Chizu Yokoi Yasushi Sugiura Hideki Ishikawa Yoji Takeuchi Yoshibumi Kaneko Yutaka Saito | 2011 | Gastroenterology2011，，6： | 4 |
| 3 | Body mass index correlated with forced expiratory volume in 1 second/forced vital capacity in a population with a relatively low prevalence of obesity显示文摘背景肥胖是在世界上的最普通的新陈代谢的疾病。然而,在肥胖之间的关系和肺功能充分没被理解。尽管几纵的研究证明了那在身体增加,重量能在肺的功能导致减小,这是否并且是否高是有日本人口的盒子身体团索引( BMI )地位独自代表现在的学习的 unclear.The 目的是在日本病人的呼吸量测定法在一般诊所测量的肺功能上估计 BMI 的效果的妨碍的肺机能障碍遗体的一个适当预言者。我们屏蔽请教了一般 clinics.Methods 题目的病人上的测量 BMI 和执行呼吸量测定法包括了 1231 个病人 40 岁(吝啬的年龄(65. | Susumu Fukahori Hiroto Matsuse Nobom Takamura Tomoko Tsuchida Tetsuya Kawano Chizu Fukushima Senjyu Hideaki Shigeru Kohno | 2010 | Chinese Medical Journal2010，，20： | 3 |
| 4 | The Current State of Diagnosis and Treatment for Early Gastric Cancer显示文摘 | Tomoyuki Yada Chizu Yokoi Naomi Uemura Tony C. K. Tham | 2013 | Diagnostic and Therapeutic Endoscopy2013，，： | 3 |
| 5 | Metachronous gastric cancers after endoscopic resection: how effective is annual endoscopic surveillance?显示文摘 | Takeshi Nakajima Ichiro Oda Takuji Gotoda Hisanao Hamanaka Takako Eguchi Chizu Yokoi Daizo Saito | 2006 | Gastric Cancer2006，，2： | 2 |
| 6 | Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity显示文摘BACKGROUND Endoscopy-based Kyoto classification for gastritis and pathological topographic distribution of neutrophil infiltration are correlated with gastric cancer risk.AIM To investigate the association between Kyoto classification and the topographic distribution of neutrophil activity.METHODS Kyoto classification score,ranging from 0 to 8,consisted of atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness.Neutrophil activity was scored according to the updated Sydney System using biopsy samples obtained from the greater curvature of the corpus and the antrum.The participants were divided into four categories,inactive stomach,antrumpredominant gastritis,pangastritis,and corpus-predominant gastritis,based on the topographic distribution of neutrophil activity.Effects of sex,age,body mass index,drinking habit,smoking habit,family history of gastric cancer,serum Helicobacter pylori(H.pylori)antibody,and Kyoto score on topography of neutrophil infiltration were analyzed.RESULTS A total of 327 patients(comprising 50.7%women,with an average age of 50.2 years)were enrolled in this study.H.pylori infection rate was 82.9%with a mean Kyoto score of 4.63.The Kyoto score was associated with the topographic distribution of neutrophil activity.Kyoto scores were significantly higher in the order of inactive stomach,antrum-predominant gastritis,pangastritis,and corpuspredominant gastritis(3.05,4.57,5.21,and 5.96,respectively).Each individual score of endoscopic findings(i.e.,atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness)was correlated with the topographic distribution of neutrophil activity.On multivariate analysis,the Kyoto score,age,and serum H.pylori antibody were independently associated with the topographic distribution of neutrophil activity.CONCLUSION The Kyoto classification score was associated with the topographic distribution of neutrophil activity. | Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Yoshiki Sakaguchi Yousuke Nakai Hidenobu Watanabe Hidekazu Suzuki Chizu Tanikawa Koichi Matsuda Kazuhiko Koike | 2020 | World Journal of Gastroenterology2020，26，34： | 2 |
| 7 | Endoscopic submucosal dissection allows curative resection of locally recurrent early gastric cancer after prior endoscopic mucosal resection显示文摘 | Chizu Yokoi Takuji Gotoda Hisanao Hamanaka Ichiro Oda | 2006 | Gastrointestinal Endoscopy2006，，： | 2 |
| 8 | A Multicenter Survey of the Management After Gastric Endoscopic Submucosal Dissection Related to Postoperative Bleeding显示文摘 | Osamu Goto Mitsuhiro Fujishiro Ichiro Oda Naomi Kakushima Yorimasa Yamamoto Yosuke Tsuji Ken Ohata Takashi Fujiwara Junko Fujiwara Naoki Ishii Chizu Yokoi Shinichi Miyamoto Toshiyuki Itoh Shinji Morishita Takuji Gotoda Kazuhiko Koike | 2012 | Digestive Diseases and Sciences2012，，2： | 2 |
| 9 | SJWD14101600000482显示文摘 | Naoyoshi Nagata Ryota Niikura Tomonori Aoki Takuro Shimbo Yoshihiro Kishida Katsunori Sekine Shohei Tanaka Kazuhiro Watanabe Toshiyuki Sakurai Chizu Yokoi Junichi Akiyama Mikio Yanase Masashi Mizokami Naomi Uemura | 2014 | J Gastroenterol Hepatol2014，，10： | 2 |
| 10 | Lower GI bleeding risk of nonsteroidal anti-inflammatory drugs and antiplatelet drug use alone and the effect of combined therapy显示文摘 | Naoyoshi Nagata Ryota Niikura Tomonori Aoki Takuro Shimbo Yoshihiro Kishida Katsunori Sekine Shohei Tanaka Hidetaka Okubo Kazuhiro Watanabe Toshiyuki Sakurai Chizu Yokoi Junichi Akiyama Mikio Yanase Masashi Mizokami Naomi Uemura | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 11 | A novel control method for nitritation: The domination of ammonia-oxidizing bacteria by high concentrations of inorganic carbon in an airlift-fluidized bed reactor显示文摘 | Takaaki Tokutomi Chizu Shibayama Satoshi Soda Michihiko Ike | 2010 | Water Research2010，，14： | 1 |
| 12 | Systematic analysis of postadministrative saiboku-to wrine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine显示文摘 | Masato H Kitaro O Chizu T | 1997 | Biome Chromastogra1997，11，： | 1 |
| 13 | Synthesis and properties of some novel high birefringence phenylacetylene liquid crystal materials with lateral substitutes显示文摘 | Chizu S Kazunori 1 Naoto K etal | 2001 | Liquid Crystals2001，28，8： | 1 |
| 14 | Devices for Facial AestheticImprovement in the Treatment of Skeletal Mandibular Protrusion 显示文摘 | Satoshi Yokoo Takahide Komori Chizu Tateishi | 2002 | Aesthetic PlasticSurgery2002，26，4： | 1 |
| 15 | Metachronous gastric cancers after endoscopic resection: how effective is annual endoscopic surveillance?显示文摘 | Takeshi Nakajima Ichiro Oda Takuji Gotoda Hisanao Hamanaka Takako Eguchi Chizu Yokoi Daizo Saito | 2006 | Gastric Cancer2006，，2： | 1 |
| 16 | Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining显示文摘 | Yuuko Ninomiya Keiichiro Suzuki Chizu Ishii | 2004 | Proc Natl Acad Sci USA2004，101，12： | 1 |
| 17 | Impact of discontinuing non-steroidal antiinflammatory drugs on long-term recurrence in colonic diverticular bleeding显示文摘AIM: To determine the effect of discontinuing nonsteroidal antiinflammatory drugs(NSAIDs) on recurrence in long-term follow-up patients with colonic diverticular bleeding(CDB).METHODS: A cohort of 132 patients hospitalized for CDB examined by colonoscopy was prospectively enrolled. Comorbidities, lifestyle, and medications(NSAIDs, low-dose aspirin, antiplatelet agents, anticoagulants, acetaminophen, and corticosteroids) were assessed. After discharge, patients were requested to visit the hospital on scheduled days during the followup period. The Kaplan-Meier method was used to estimate recurrence.RESULTS: Median follow-up was 15 mo. The probability of recurrence at 1, 6, 12, and 24 mo was 3.1%, 19%, 27%, and 38%, respectively. Of the 41 NSAID users on admission, 26(63%) discontinued NSAID use at discharge. Many of the patients who could discontinue NSAIDs were intermittent users, and could be switched to alternative therapies, such as acetaminophen or an antiinflammatory analgesic plaster. The probability of recurrence at 12 mo was 9.4% in discontinuing NSAID users compared with 77% in continuing users(P < 0.01, log-rank test). The hazard ratio for recurrence in the discontinuing NSAIDs users was 0.06 after adjusting for age > 70 years, right-sided diverticula, history of hypertension, and hemodialysis. No patients developed cerebrocardiovascular events during follow-up.CONCLUSION: There is a substantial recurrence rate after discharge among patients hospitalized for diverticular bleeding. Discontinuation of NSAIDs is an effective preventive measure against recurrence. This study provides new information on risk reduction strategies for diverticular bleeding. | Naoyoshi Nagata Ryota Niikura Tomonori Aoki Takuro Shimbo Katsunori Sekine Hidetaka Okubo Kazuhiro Watanabe Toshiyuki Sakurai Chizu Yokoi Junichi Akiyama Mikio Yanase Masashi Mizokami Naomi Uemura | 2015 | World Journal of Gastroenterology2015，21，4： | 1 |
| 18 | An efficient diagnostic strategy for small, depressed early gastric cancer with magnifying narrow-band imaging: a post-hoc analysis of a prospective randomized controlled trial显示文摘 | Shinya Yamada Hisashi Doyama Kenshi Yao Noriya Uedo Yasumasa Ezoe Ichiro Oda Kazuhiro Kaneko Yoshiro Kawahara Chizu Yokoi Yasushi Sugiura Hideki Ishikawa Yoji Takeuchi Yutaka Saito Manabu Muto | 2013 | Gastrointestinal Endoscopy2013，，： | 1 |
| 19 | Structural characterization of copper( I ) complexes supported by β- dlketiminate ligands with different substitution patterns 显示文摘 | Chizu S Yoshimitsu T Nagatoshi N | 2006 | Bull Chem Soc Jpn2006，79，： | 1 |
| 20 | Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis显示文摘 | Mika Watanabe Jun Kato Izumi Inoue Noriko Yoshimura Takeichi Yoshida Chizu Mukoubayashi Hisanobu Deguchi Shotaro Enomoto Kazuki Ueda Takao Maekita Mikitaka Iguchi Hideyuki Tamai Hirotoshi Utsunomiya Nobutake Yamamichi Mitsuhiro Fujishiro Masataka Iwane Ta | 2012 | Int J Cancer2012，，11： | 1 |
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