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45篇 您的检索式:作者名="Chenglong Huang"
    题名 作者 年代 出处 被引量
1The Sunway TaihuLight supercomputer: system and applications显示文摘The Sunway Taihu Light supercomputer is the world's first system with a peak performance greater than 100 PFlops. In this paper, we provide a detailed introduction to the Taihu Light system. In contrast with other existing heterogeneous supercomputers, which include both CPU processors and PCIe-connected many-core accelerators(NVIDIA GPU or Intel Xeon Phi), the computing power of Taihu Light is provided by a homegrown many-core SW26010 CPU that includes both the management processing elements(MPEs)and computing processing elements(CPEs) in one chip. With 260 processing elements in one CPU, a single SW26010 provides a peak performance of over three TFlops. To alleviate the memory bandwidth bottleneck in most applications, each CPE comes with a scratch pad memory, which serves as a user-controlled cache. To support the parallelization of programs on the new many-core architecture, in addition to the basic C/C++and Fortran compilers, the system provides a customized Sunway Open ACC tool that supports the Open ACC2.0 syntax. This paper also reports our preliminary efforts on developing and optimizing applications on the Taihu Light system, focusing on key application domains, such as earth system modeling, ocean surface wave modeling, atomistic simulation, and phase-field simulation.Haohuan FU Junfeng LIAO Jinzhe YANG Lanning WANG Zhenya SONG Xiaomeng HUANG Chao YANG Wei XUE Fangfang LIU Fangli QIAO Wei ZHAO Xunqiang YIN Chaofeng HOU Chenglong ZHANG Wei GE Jian ZHANG Yangang WANG Chunbo ZHOU Guangwen YANG 2016Science China(Information Sciences)2016,59,7:45
2Genome-Wide Association Studies of Image Traits Reveal Genetic Architecture of Drought Resistance in Rice显示文摘理解植物怎么对干旱作出回应能有益于繁殖的干旱抵抗(医生) 。用一台非破坏性的 phenotyping 设备,为 507 米饭就职的 51 个基于图象的特点(i 特点) 被提取。这些 i 特点能被用来监视干旱回答 ? 并且高评估医生可遗传性和这些特点的大变化在自然人口在干旱应力下面被观察。染色体宽的协会研究(GWAS )?i 特点和传统的医生特点识别了 470 协会 loci,某包含知道医生相关的基因。这 470 loci, 443 loci (94%) 用 i 特点被识别, 437 loci (93%) 与以前报导的医生相关的量的特点 loci,和 313 loci (66.6%)co 局部性被 GWAS reproducibly 在不同的年里识别。协会网络,基于 GWAS 建立了结果,揭示中心 i 特点和中心 loci。这表明把的可行性和必要性复杂医生特点进可继承、简单的 i 特点。作为原则的证明,我们说明了这条综合途径的力量以前识别 unreported 医生相关的基因。OsPP15 与中心 i 特点被联系,并且它在医生的角色被基因转变实验证实。而且, i 特点能被用于医生连接分析,并且 69 个 i 特点地点协会被 recombinant 的 GWAS 和连接分析识别生来的线人口。最后,我们证实了 i 特点的关联在这个领域里搀。我们的学习为医生为原因的基因的基因解剖和发现提供一条有希望的新奇途径。Zilong Guo Wanneng Yang Yu Chang Xiaosong Ma Haifu Tu Fang Xiong Ni Jiang Hui Feng Chenglong Huang Peng Yang Hu Zhao Guoxing Chen Hongyan Liu Lijun Luo Honghong Hu Qian Liu Lizhong Xiong 2018Molecular Plant2018,11,6:21
3Determination of rice panicle numbers during heading by multi-angle imaging显示文摘Plant phenomics has the potential to accelerate progress in understanding gene functions and environmental responses. Progress has been made in automating high-throughput plant phenotyping. However, few studies have investigated automated rice panicle counting. This paper describes a novel method for automatically and nonintrusively determining rice panicle numbers during the full heading stage by analyzing color images of rice plants taken from multiple angles. Pot-grown rice plants were transferred via an industrial conveyer to an imaging chamber. Color images from different angles were automatically acquired as a turntable rotated the plant. The images were then analyzed and the panicle number of each plant was determined. The image analysis pipeline consisted of extracting the i2 plane from the original color image, segmenting the image, discriminating the panicles from the rest of the plant using an artificial neural network, and calculating the panicle number in the current image. The panicle number of the plant was taken as the maximum of the panicle numbers extracted from all 12 multi-angle images. A total of 105 rice plants during the full heading stage were examined to test the performance of the method. The mean absolute error of the manual and automatic count was 0.5, with 95.3% of the plants yielding absolute errors within ± 1. The method will be useful for evaluating rice panicles and will serve as an important supplementary method for high-throughput rice phenotyping.Lingfeng Duan Chenglong Huang Guoxing Chen Lizhong Xiong Qian Liu Wanneng Yang 2015The Crop Journal2015,3,3:18
4Human ACE2-Functionalized Gold“Virus-Trap”Nanostructures for Accurate Capture of SARS-CoV-2 and Single-Virus SERS Detection显示文摘The current COVID-19 pandemic urges the extremely sensitive and prompt detection of SARS-CoV-2 virus.Here,we present a Human Angiotensin-converting-enzyme 2(ACE2)-functionalized gold“virus traps”nanostructure as an extremely sensitive SERS biosensor,to selectively capture and rapidly detect S-protein expressed coronavirus,such as the current SARS-CoV-2 in the contaminated water,down to the single-virus level.Such a SERS sensor features extraordinary 106-fold virus enrichment originating from high-affinity of ACE2 with S protein as well as“virus-traps”composed of oblique gold nanoneedles,and 109-fold enhancement of Raman signals originating from multi-component SERS effects.Furthermore,the identification standard of virus signals is established by machine-learning and identification techniques,resulting in an especially low detection limit of 80 copies mL^(−1) for the simulated contaminated water by SARS-CoV-2 virus with complex circumstance as short as 5 min,which is of great significance for achieving real-time monitoring and early warning of coronavirus.Moreover,here-developed method can be used to establish the identification standard for future unknown coronavirus,and immediately enable extremely sensitive and rapid detection of novel virus.Yong Yang Yusi Peng Chenglong Lin Li Long Jingying Hu Jun He Hui Zeng Zhengren Huang Zhi-Yuan Li Masaki Tanemura Jianlin Shi John R.Lombardi Xiaoying Luo 2021Nano-Micro Letters2021,13,7:6
5Nondestructive 3D Image Analysis Pipeline to Extract Rice Grain Traits Using X-Ray Computed Tomography显示文摘The traits of rice panicles play important roles in yield assessment,variety classification,rice breeding,and cultivation management.Most traditional grain phenotyping methods require threshing and thus are time-consuming and labor-intensive;moreover,these methods cannot obtain 3D grain traits.In this work,based on X-ray computed tomography,we proposed an image analysis method to extract twenty-two 3D grain traits.After 104 samples were tested,the R^(2) values between the extracted and manual measurements of the grain number and grain length were 0.980 and 0.960,respectively.We also found a high correlation between the total grain volume and weight.In addition,the extracted 3D grain traits were used to classify the rice varieties,and the support vector machine classifier had a higher recognition accuracy than the stepwise discriminant analysis and random forest classifiers.In conclusion,we developed a 3D image analysis pipeline to extract rice grain traits using X-ray computed tomography that can provide more 3D grain information and could benefit future research on rice functional genomics and rice breeding.Weijuan Hu Can Zhang Yuqiang Jiang Chenglong Huang Qian Liu Lizhong Xiong Wanneng Yang Fan Chen 2020Plant Phenomics2020,2,1:6
6Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts显示文摘Vascular diseases are the most prevalent cause of ischemic necrosis of tissue and organ,which even result in dysfunction and death.Vascular regeneration or artificial vascular graft,as the conventional treatment modality,has received keen attentions.However,small-diameter(diameter<4 mm)vascular grafts have a high risk of thrombosis and intimal hyperplasia(IH),which makes long-term lumen patency challengeable.Endothelial cells(ECs)form the inner endothelium layer,and are crucial for anti-coagulation and thrombogenesis.Thus,promoting in situ endothelialization in vascular graft remodeling takes top priority,which requires recruitment of endothelia progenitor cells(EPCs),migration,adhesion,proliferation and activation of EPCs and ECs.Chemotaxis aimed at ligands on EPC surface can be utilized for EPC homing,while nanofibrous structure,biocompatible surface and cell-capturing molecules on graft surface can be applied for cell adhesion.Moreover,cell orientation can be regulated by topography of scaffold,and cell bioactivity can be modulated by growth factors and therapeutic genes.Additionally,surface modification can also reduce thrombogenesis,and some drug release can inhibit IH.Considering the influence of macrophages on ECs and smooth muscle cells(SMCs),scaffolds loaded with drugs that can promote M2 polarization are alternative strategies.In conclusion,the advanced strategies for enhanced long-term lumen patency of vascular grafts are summarized in this review.Strategies for recruitment of EPCs,adhesion,proliferation and activation of EPCs and ECs,anti-thrombogenesis,anti-IH,and immunomodulation are discussed.Ideal vascular grafts with appropriate surface modification,loading and fabrication strategies are required in further studies.Yu Zhuang Chenglong Zhang Mengjia Cheng Jinyang Huang Qingcheng Liu Guangyin Yuan Kaili Lin Hongbo Yu 2021Bioactive Materials2021,6,6:5
7Concept of the solar ring mission:An overview显示文摘The concept of the Solar Ring mission was gradually formed from L5/L4 mission concept, and the proposal of its pre-phase study was funded by the National Natural Science Foundation of China in November 2018 and then by the Strategic Priority Program of Chinese Academy of Sciences in space sciences in May 2019. Solar Ring mission will be the first attempt to routinely monitor and study the Sun and inner heliosphere from a full 360-degree perspective in the ecliptic plane. The current preliminary design of the Solar Ring mission is to deploy six spacecraft, grouped in three pairs, on a sub-AU orbit around the Sun. The two spacecraft in each group are separated by about 30?and every two groups by about 120?. This configuration with necessary science payloads will allow us to establish three unprecedented capabilities:(1) determine the photospheric vector magnetic field with unambiguity,(2) provide 360-degree maps of the Sun and the inner heliosphere routinely, and(3) resolve the solar wind structures at multiple scales and multiple longitudes. With these capabilities, the Solar Ring mission aims to address the origin of solar cycle, the origin of solar eruptions, the origin of solar wind structures and the origin of severe space weather events. The successful accomplishment of the mission will advance our understanding of the star and the space environment that hold our life and enhance our capability of expanding the next new territory of human.WANG YuMing JI HaiSheng WANG YaMin XIA LiDong SHEN ChengLong GUO JingNan ZHANG QuanHao HUANG ZhengHua LIU Kai LI XiaoLei LIU Rui WANG JingXiu WANG Shui 2020Science China(Technological Sciences)2020,63,9:4
8Fossil leaves of Berhamniphyllum(Rhamnaceae) from Markam,Tibet and their biogeographic implications显示文摘A new occurrence of buckthorn fossil leaves is reported from the upper Eocene strata of Markam Basin,southeastern Tibet,China.The leaf margin is either entire or slightly sinuous.Secondary veins are regularly spaced,forming eucamptodromous venation.These secondaries exist as straight lines from midvein to near margin and then arch abruptly upward and enter into a margin vein.The tertiary veins are densely spaced and parallel,and are percurrent to secondary veins.This leaf architecture conforms with Berhamniphyllum Jones and Dilcher,an extinct fossil genus reported from America.Our fossils are characterized by their dense secondaries,with secondary veins on the upper half portion of the blade accounting for over 40%of all secondaries.A new species,Berhamniphyllum junrongiae Z.K.Zhou,T.X.Wang et J.Huang sp.nov.,is proposed.Further analysis shows that confident assignment among Rhamnidium,Berchemia,and Karwinskia cannot be made based on leaf characters alone.Berhamniphyllum might represent an extinct common ancestor of these genera.In this study,several fossil Berchemia from Yunnan and Shandong are emended and reassigned to Berhamniphyllum.A new complex,namely the Berchemia Complex,is proposed based on morphology,molecular evidence,and the fossil record.This complex contains the fossil leaves of Rhamnidium,Karwinskia,Berchemia,and Berhamniphyllum.The historical biogeography of the Berchemia Complex is also discussed in this paper.This complex might have originated in the late Cretaceous in Colombia,South America,and dispersed to North America via Central America during the Eocene.Subsequently,the complex moved from North America to East Asia via the Bering Land Bridge no later than the late Eocene.Besides,the complex migrated from North America to Europe via the North Atlantic Land Bridge and then migrated further to Africa.In East Asia,it first appeared in Markam on the Qinghai-Tibetan Plateau,and then dispersed to other regions of Asia.Zhekun ZHOU Tengxiang WANG Jian HUANG Jia LIU Weiyudong DENG Shihu LI Chenglong DENG Tao SU 2020Science China Earth Sciences2020,63,2:4
9Charge‑Transfer Resonance and Electromagnetic Enhancement Synergistically Enabling MXenes with Excellent SERS Sensitivity for SARS‑CoV‑2 S Protein Detection显示文摘The outbreak of coronavirus disease 2019 has seriously threatened human health.Rapidly and sensitively detecting SARSCoV-2 viruses can help control the spread of viruses.However,it is an arduous challenge to apply semiconductor-based substrates for virus SERS detection due to their poor sensitivity.Therefore,it is worthwhile to search novel semiconductor-based substrates with excellent SERS sensitivity.Herein we report,for the first time,Nb2C and Ta2C MXenes exhibit a remarkable SERS enhancement,which is synergistically enabled by the charge transfer resonance enhancement and electromagnetic enhancement.Their SERS sensitivity is optimized to 3.0×10^6 and 1.4×10^6 under the optimal resonance excitation wavelength of 532 nm.Additionally,remarkable SERS sensitivity endows Ta2C MXenes with capability to sensitively detect and accurately identify the SARS-CoV-2 spike protein.Moreover,its detection limit is as low as 5×10^−9 M,which is beneficial to achieve real-time monitoring and early warning of novel coronavirus.This research not only provides helpful theoretical guidance for exploring other novel SERS-active semiconductor-based materials but also provides a potential candidate for the practical applications of SERS technology.Yusi Peng Chenglong Lin Li Long Tanemura Masaki Mao Tang Lili Yang Jianjun Liu Zhengren Huang Zhiyuan Li Xiaoying Luo John RLombardi Yong Yang 2021Nano-Micro Letters2021,13,3:3
10Colour compound lenses for a portable fluorescence microscope显示文摘In this article,we demonstrated a handheld smartphone fluorescence microscope(HSFM)that integrates dualfunctional polymer lenses with a smartphone.The HSFM consists of a smartphone,a field-portable illumination source,and a dual-functional polymer lens that performs both optical imaging and filtering.Therefore,compared with the existing smartphone fluorescence microscope,the HSFM does not need any additional optical filters.Although fluorescence imaging has traditionally played an indispensable role in biomedical and clinical applications due to its high specificity and sensitivity for detecting cells,proteins,DNAs/RNAs,etc.,the bulky elements of conventional fluorescence microscopes make them inconvenient for use in point-of-care diagnosis.The HSFM demonstrated in this article solves this problem by providing a multifunctional,miniature,small-form-factor fluorescence module.This multifunctional fluorescence module can be seamlessly attached to any smartphone camera for both bright-field and fluorescence imaging at cellular-scale resolutions without the use of additional bulky lenses/filters;in fact,the HSFM achieves magnification and light filtration using a single lens.Cell and tissue observation,cell counting,plasmid transfection evaluation,and superoxide production analysis were performed using this device.Notably,this lens system has the unique capability of functioning with numerous smartphones,irrespective of the smartphone model and the camera technology housed within each device.As such,this HSFM has the potential to pave the way for realtime point-of-care diagnosis and opens up countless possibilities for personalized medicine.Bo Dai Ziao Jiao Lulu Zheng Hunter Bachman Yongfeng Fu Xinjun Wan Yule Zhang Yu Huang Xiaodian Han Chenglong Zhao Tony Jun Huang Songlin Zhuang Dawei Zhang 2019Light(Science & Applications)2019,8,1:3
11Fossil seeds of Euryale(Nymphaeaceae) indicate a lake or swamp environment in the late Miocene Zhaotong Basin of southwestern China显示文摘Euryale(Nymphaeaceae) is a monotypic genus distributed in eastern Asia, but fossils in its native distribution are sparse as compared to Europe where the genus has disappeared. Here, we describe a new fossil species, Euryale yunnanensis sp. nov., from the late Miocene Zhaotong Basin in southwestern China on the basis of seed remains. Characteristics including an ellipsoidal to almost spherical shape,a smooth surface, a germination cap that covers the micropyle, the separation of the hilum and germination cap(micropyle), elliptic testa surface cells with undulate margins and thickened cell walls collectively indicate a close affinity with the genus Euryale in Nymphaeaceae. Comparisons ofseed morphology and anatomy demonstrate that the newly described fossil species differs from modern and other fossil species of Euryale and thus verify the assignment to a new fossil species. As the modern Euryale is an aquatic plant,preferably living in swamps and lakes with shallow and stable water, we hypothesize that a lake and/or swamp environment with shallow water was present near Shuitangba in the Zhaotong Basin, where the Shuitangba hominoid lived during the late Miocene. This inference is generally consistent with paleoenvironmental data extracted from avian, fish, frog, turtle and crocodile fossils, as well as from aquatic pollen. The fossil history suggests a comparatively recent(Miocene) emergence of Euryale, which is roughly in agreement with the divergence time inferred from the molecular information.Yongjiang Huang Xueping Ji Tao Su Li Wang Chenglong Deng Wenqi Li Hongfen Luo Zhekun Zhou 2015Science Bulletin2015,60,20:3
12Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian 2017Molecular Plant2017,10,12:3
13A high-performance bio-tissue imaging method using air flow-assisted desorption electrospray ionization coupled with a high-resolution mass spectrometer显示文摘Mass spectrometry imaging (MSI) technology can simultaneously obtain the spatial distribution of thousands of chemical compounds and has unique advantages compared to other techniques that allow mapping the surface of bio-tissue. Here, we combined an air flow-assisted desorption electrospray ionization (AFADESI) MSI device with a high-resolution mass spectrometer to optimize the system parameters and achieve more accurate spatial distribution characteristics for compounds of interest while investigating bio-tissue sections. The platform set-up, required instrumentation, sample pretreatment, parameter optimization and bio-tissue characterization are described and discussed.Finally, the parameter conditions that can provide optimal ionic intensity and enhanced resolution were confirmed. The reasonable resolution and sensitivity improvements of AFADESI-MSI have been achieved through tandem a high-resolution mass spectrometer system, therefore, it would be a promising technique for the bio-tissue imaging analysis.Yiwei Lv Tiegang Li Chengan Guo Chenglong Sun Fei Tang Luojiao Huang Zhigang Luo Xin Li Ruiping Zhang Qingce Zang Jiuming He Zeper AbliZ 2019Chinese Chemical Letters2019,30,2:2
14A rapid and sensitive UPLC–MS/MS method for quantitative determination of arformoterol in rat plasma, lung and trachea tissues显示文摘A rapid and sensitive ultra-performance liquid chromatography-tandem mass spectrometry(UPLC–MS/MS) method was developed and fully validated for determination of arformoterol in rat plasma, lung and trachea tissues. The chromatographic separation was performed on an Agilent XDB C8 column with gradient elution by using acetonitrile and 0.1% formic acid water. The method presented high sensitivity(LLOQ of 1.83 pg/mL for plasma and 3.90 pg/mL for lung and trachea tissue homogenates) and great linearity over the range of 1.83–458 pg/mL for plasma, 13.9–1560 pg/mL for lung and trachea tissue homogenates. No carry over effect and matrix effect were observed. The intra-and inter-day precision/accuracy were within ±15% at three quality control concentration levels. This robust method was successfully applied to the pharmacokinetic, lung and trachea tissue distribution study after inhalation administration of arformoterol tartrate inhalation solution(50 m g/kg). The in vivo information indicate that arformoterol can be rapidly absorbed into blood through respiratory systems, lung and trachea tissue maintain a certain amount of arformoterol in 1 h after dosing.Chenglong Sun Jiuming He Hongbo Wu Xiaowei Song Jiangshuo Li Luojiao Huang Xiaoyu Xu Manjiangcuo Wang Ruiping Zhang Zeper Abliz 2018Chinese Chemical Letters2018,29,8:2
15Geo-location for Ground Target with Multiple Observations Using Unmanned Aerial Vehicle显示文摘In order to improve the target location accuracy of unmanned aerial vehicle(UAV),a novel target location method using multiple observations is proposed.Firstly,the camera intrinsic parameters are calibrated.Then,the weighted least squares estimation is used to improve the localization precision because the traditional crossover method is vulnerable to noise and has low precision.By repeatedly measuring the same target point,a nonlinear observation equation is established and then covered to linear equations using Taylor expansion.The weighted matrix is obtained according to the height of the measurement point and the camera optic axis pointing angle,and then the weighted least squares estimation is used to calculate the target position iteratively.Finally,the effectiveness and robustness of this method is verified by numerical simulation and flight test.The results show that this method can effectively improve the precision of target location.Xu Cheng He Chenglong Huang Daqing 2018Transactions of Nanjing University of Aeronautics and Astronautics2018,35,5:1
16Experimental and modeling study of the auto-ignition of n -heptane/ n -butanol mixtures显示文摘Jiaxiang Zhang Shaodong Niu Yingjia Zhang Chenglong Tang Xue Jiang Erjiang Hu Zuohua Huang 2013Combustion and Flame2013,,1:1
17Comparative proteomic analysis of plasma from bipolar depression and depressive disorder: identification of proteins associated with immune regulatory显示文摘Jin Chen (1) (2) (3) ChengLong Huang (2) (3) (5) YiRen Song (1) (2) (3) HaiYang Shi (1) (2) (3) Dong Wu (2) (3) (5) YongTao Yang (2) (3) (4) ChengLong Rao (2) (3) (7) Li Liao (2) (3) (5) You Wu (2) (3) (6) JianYong Tang (2) (3) (5) Ke Cheng (1) (2) (3) Jian Zhou (2) (3) Peng Xie (1) (2) (3) 2015Protein & Cell2015,6,12:1
18Cretaceous palynomorphs of Taiwan (2) -Taxonomic treatment 显示文摘 Huang Tsengchieng 1994Taiwania1994,39,34:1
19Pollen analysis of the Cretaceous sediments in Taiwan 显示文摘 Huang Tsengchieng 1995Taiwania1995,40,3:1
20Numerical study on combustion of diluted methanol-air premixed mixtures显示文摘The effect of nitrogen dilution on the premixed combustion characteristics and flame structure of laminar premixed methanol-air-nitrogen mixtures are analyzed numerically based on an extended methanol oxidation mechanism. The laminar burning velocities, the mass burning fluxes, the adiabatic flame temperature, the global activation temperature, the Zeldovich number, the effective Lewis number and the laminar flame structure of the methanol-air-nitrogen mixtures are obtained under different nitrogen dilution ratios. Comparison between experiments and numerical simulations show that the extended methanol oxidation mechanism can well reproduce the laminar burning velocities for lean and near stoichiometric methanol-air-nitrogen mixtures. The laminar burning velocities and the mass burning fluxes decrease with the increase of nitrogen dilution ratio and the effect is more obvious for the lean mixture. The effective Lewis number of the mixture increases with the increase of nitrogen dilution ratio, and the diffusive-thermal instability of the flame front is decreased by the nitrogen addition. Nitrogen addition can suppress the hydrodynamic instability of methanol-air-nitrogen flames. The decrease of the mole fraction of OH and H is mainly responsible for the suppressed effect of nitrogen diluent on the chemical reaction in the methanol-air-nitrogen laminar premixed flames, and the NOx and formaldehyde emissions are decreased by the nitrogen addition.Zheng JianJun Zhang ZhiYuan Huang ZuoHua Hu ErJiang Tang ChengLong Wang JinHua 2010Chinese Science Bulletin2010,55,9:1
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