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| 1 | Elastic band ligation of hemorrhoids:Flexible gastroscope or rigid proctoscope?显示文摘AIM: To compare rigid proctoscope and flexible endoscope for elastic band ligation of internal hemorrhoids. METHODS: Patients between 18 and 80 years old, with chronic complaints (blood loss, pain, itching or prolapse) of internal hemorrhoids of grade I-Ⅲ, were randomized to elastic band ligation by rigid proctoscope or flexible endoscope (preloaded with 7 bands). Patients were re- treated every 6 wk until the cessation of complaints. Evaluation by three-dimensional anal endosonography was performed. RESULTS: Forty-one patients were included (median age 52.0, range 27-79 years, 20 men). Nineteen patients were treated with a rigid proctoscope and twenty two with a flexible endoscope. Twenty-nine patients had grade I hemorrhoids, 9 patients had grade Ⅱ hemorrhoids and 3 patients had grade Ⅲ hemorrhoids. All patients needed a minimum of 1 treatment and a maximum of 3 treatments. A median of 4.0 bands was used in the rigid proctoscope group and a median of 6.0 bands was used in the flexible endoscope group (P < 0.05). Pain after ligation tended to be more frequent in patients treated with the flexible endoscope (first treatment: 3 vs 10 patients, P < 0.05). Three- dimensional endosonography showed no sphincter defects or alterations in submucosal thickness. CONCLUSION: Both techniques are easy to perform, well tolerated and have a good and fast effect. It is easier to perform more ligations with the flexible endoscope. Additional advantages of the flexible scope are the maneuverability and photographic documentation. However, treatment with the flexible endoscope might be more painful and is more expensive. | M Cazemier RJF Felt-Bersma MA Cuesta CJJ Mulder | 2007 | World Journal of Gastroenterology2007，13，4： | 12 |
| 2 | Anal plugs and retrograde colonic irrigation are helpful in fecal incontinence or constipation显示文摘AIM: To evaluate the feasibility, clinical effect and predicting factors for favorable outcome of treatment with anal plugs in fecal incontinence and retrograde colonic irrigation (RCI) in patients with fecal incontinence or constipation. METHODS: Patients who received treatment with an anal plug or RCI between 1980 and 2005 were investigated with a questionnaire. RESULTS: Of the 201 patients (93 adults, 108 children), 101 (50/) responded. Adults: anal plugs (8), five stopped immediately, one stopped after 20 mo and two used it for 12-15 mo. RCI (40, 28 fecal incontinence, 12 constipation), 63/ are still using it (mean 8.5 years), 88/ was satisfied. Younger adults (< 40 years) were more satisfied with RCI (94 / vs 65/, P = 0.05). Children: anal plugs (7), 5 used it on demand for an average of 2.5 years with satisfactory results, one stopped immediately and one after 5 years. RCI (26 fecal incontinence, 22 constipation), 90/ are still using it (mean time 6.8 years) and felt satisfi ed. Children tend to be more satisfi ed (P = 0.001). Besides age, no predictive factors for success were found. There was no difference in the outcome between patients with fecal incontinence or constipation. CONCLUSION: RCI is more often applied than anal plugs and is helpful in patients with fecal incontinence or constipation, especially for younger patients. Anal plugs can be used incidentally for fecal incontinence, especially in children. | Marcel Cazemier Richelle JF Felt-Bersma Chris JJ Mulder | 2007 | World Journal of Gastroenterology2007，13，22： | 4 |
| 3 | Retrospective analysis of old-age colitis in the Dutch inflammatory bowel disease population显示文摘AIM: To describe the characteristics of Dutch patients with chronic inflammatory bowel disease (IBD) first diagnosed above 60 years of age-a disease also known as old-age colitis (OAC) and to highlight a condition that has a similar appearance to IBD, namely segmen- tal colitis associated with diverticular disease (SCAD). METHODS: A retrospective longitudinal survey of patient demographic and clinical characteristics, disease characteristics, diagnostic methods, management and course of disease was performed. The median follow-up period was 10 years. RESULTS: Of a total of 1100 IBD patients attending the Department of Gastroenterology, 59 (5%) [median age 82 years (range 64-101); 25 male (42%)] were identified. These patients were diagnosed with ulcerative colitis (n = 37, 61%), Crohn’s disease (n = 14, 24%), and indeterminate colitis (n = 8, 15%). Remission was induced in 40 (68%) patients within a median interval of 6 mo (range 1-21) and immunosuppressive therapy was well tolerated. Histological evaluation based on many biopsy samples and the course of the disease led to other diagnosis, namely SCAD instead of IBD in five (8%) patients. CONCLUSION: OAC is not an infrequent problem for the gastroenterologist, and should be considered in the evaluation of older patients with clinical featuressuggestive of IBD. Extra awareness and extensive biopsy sampling are required in order to avoid an erroneous diagnosis purely based on histological mimicry of changes seen in SCAD, when diagnosing IBD in the presence of diverticulosis coli. | Muhammed Hadithi Marcel Cazemier Gerrit A Meijer Elisabeth Bloemena Richel J Felt-Bersma Chris J Mulder Stephan GM Meuwissen Amado Salvador Pea Adriaan A van Bodegraven | 2008 | World Journal of Gastroenterology2008，14，20： | 3 |
| 4 | Fuzzy k-means clustering of fields in an elementary catchment and extrapolation to a larger area显示文摘 | LAGACHERIE P CAZEMIER D R van GAANS P F | 1997 | Geoderma1997，77，2： | 1 |
| 5 | Sulfonamide an-tibodies :from specific polyclonals to generic mono-clonals显示文摘 | Haasnoot W Cazemier G Du P | 2000 | Food Agric Immunol2000，12，1： | 1 |
| 6 | Immunochemical detection of aminoglycosides in milk andkidney显示文摘 | Hassnoot W Stouten P Cazemier G | 1999 | The Analyst1999，124，： | 1 |
| 7 | Proper orthogonal decomposition and low-dimensional models for driven cavity显示文摘 | Cazemier W Verstappen R W C P | 1998 | Physics of Fluids1998，10，7： | 1 |
| 8 | Development of a robe enzyme immunoassay for 'on-site' screening of urine samples in the presence of beta-agonists显示文摘 | HAASNOOT W STREPPEL L CAZEMIER G | 1996 | Analyst1996，121，： | 1 |
| 9 | Development of a tube enzyme immunoassay for 'on-site' screening of urine samples in the presence of beta-agonists显示文摘 | Haasnoot W Streppel L Cazemier G | | 0，，： | 1 |
| 10 | Sulfonamide antibodies:from speific polyclonals to generic monoclonals显示文摘 | Cazemier G Haasnoot W Du P | | 0，，8： | 1 |
| 11 | Development of a one step strip test for the detection of sulfadimidine residues显示文摘 | VERHEIJEN R STOUTEN P CAZEMIER G | 1998 | Analyst1998，123，： | 1 |
| 12 | Direct versus competitive biosensor immunoassays for the detection of (dihydro)streptomycin residues in milk显示文摘 | Haasnoot W Loomans EMG Cazemier G | 2002 | Food Agric Immunol2002，14，： | 1 |
| 13 | Application of an enzyme immunoassay for the determination of sulphamethazine (sulphadimidine) residues in swine urine and plasma and their use as predictors of the level in edible tissue显示文摘 | HAASNOOT W KORSRUD G O CAZEMIER G ctal | 1996 | Food Additives and Contaminants1996，13，7： | 1 |
| 14 | Atrophy and defects detection of the external anal sphincter: comparison between three-dimensional anal endosonography and endoanal magnetic resonance imaging 显示文摘 | Cazemier M Terra MP Stoker J | 2006 | Dis Colon Rectum2006，49，1： | 1 |
| 15 | Sulfonamide antibodies:from speific polyclonals to generic monoclonals显示文摘 | Cazemier G Du P | 2000 | Food Agirc Immunol2000，12，： | 1 |
| 16 | Sulfonamide an-tibodies :from specific polyclonals to generic mono-clonals显示文摘 | Haasnoot W Cazemier G Du P | 2000 | Food Agric Immunol2000，12，1： | 1 |
| 17 | Monoclonal antibo-dies against a sulfathiazole derivative for the immunochemical detection of sulphonamides显示文摘 | Haasnoot W Duper J Cazemier G | 2000 | Food and Agricultural Immunology2000，12，： | 1 |
| 18 | Immunochemical detection of aminoglycosides in milk and kidney显示文摘 | HAASNOOT W STOUTEN P CAZEMIER G | 1999 | Analyst1999，124，3： | 1 |
| 19 | Sulphonamide antibodies: from specific polyclonals to generic monoclonals 显示文摘 | HAASNOOT W CAZEMIER G DU PRE J | 2000 | Food Agric Immunol2000，12，1： | 1 |
| 20 | Monoclonal antibodies against a sulfathiazole derivative for the immunochemical detection of sulfonamides显示文摘 | HAASNOOT W DU PRE J CAZEMIER G | 2000 | Food Agric Immunol2000，12，： | 1 |
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