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| 1 | Use of antibiotics in broiler production:Global impacts and alternatives显示文摘Antibiotics are used to fight bacterial infections.However, a selective pressure gave rise to bacteria resistant to antibiotics.This leaves scientists worried about the danger to human and animal health.Some strategies can be borrowed to reduce the use of antibiotics in chicken farms.Much research has been carried out to look for natural agents with similar beneficial effects of growth promoters.The aim of these alternatives is to maintain a low mortality rate, a good level of animal yield while preserving environment and consumer health.Among these, the most popular are probiotics, prebiotics, enzymes,organic acids, immunostimulants, bacteriocins, bacteriophages, phytogenic feed additives, phytoncides,nanoparticles and essential oils. | Youcef Mehdi Marie-Pierre Létourneau-Montminy Marie-Lou Gaucher Younes Chorfi Gayatri Suresh Tarek Rouissi Satinder Kaur Brar Caroline Cté Antonio Avalos Ramirez Stéphane Godbout | 2018 | Animal Nutrition2018，，2： | 19 |
| 2 | Cyclin A2:At the crossroads of cell cycle and cell invasion显示文摘Cyclin A2 is an essential regulator of the cell division cycle through the activation of kinases that participate to the regulation of S phase as well as the mitotic entry. However,whereas its degradation by the proteasome in mid mitosis was thought to be essential for mitosis to proceed,recent observations show that a small fraction of cyclin A2 persists beyond metaphase and is degraded by autophagy. Its implication in the control of cytoskeletal dynamics and cell movement has unveiled its role in the modulation of Rho A activity. Since this GTPase is involved in both cell rounding early in mitosis and later,in the formation of the cleavage furrow,this suggests that cyclin A2 is a novel actor in cytokinesis. Taken together,these data point to this cyclin as a potential mediator of cell-niche interactions whose dysregulation could be taken as a hallmark of metastasis. | Abdelhalim Loukil Caroline T Cheung Nawal Bendris Bénédicte Lemmers Marion Peter Jean Marie Blanchard | 2015 | World Journal of Biological Chemistry2015，6，4： | 6 |
| 3 | Clostridium paraputrificum septicemia and liver abscess显示文摘We report the first case of a healthy 23-year-old female who underwent an interventional radiology-guided embolization of a hepatic adenoma, which resulted in a gas forming hepatic liver abscess and septicemia by Clostridium paraputrificum. A retrospective review of Clostridial liver abscesses was performed using a Pub Med literature search, and we found 57 clostridial hepatic abscess cases. The two most commonly reported clostridial species are C. perfringens and C. septicum(64.9% and 17.5% respectively). C. perfringens cases carried a mortality of 67.6% with median survival of 11 h, and 70.2% of the C. perfringens cases experienced hemolysis. All C. septicum cases were found to have underlying liver malignancy at the time of the presentation with a mortality of only 30%. The remaining cases were caused by various Clostridium species, and this cohort's clinical course was significantly milder when compared to the above C. perfringens and C. septicum cohorts. | Yong K Kwon Faiqa A Cheema Bejon T Maneckshana Caroline Rochon Patricia A Sheiner | 2018 | World Journal of Hepatology2018，10，3： | 4 |
| 4 | A comparison of the relative efficiency of ICSI and extended culture with epididymal sperm versus testicular sperm in patients with obstructive azoospermia显示文摘This is a retrospective cohort study comparing blastocyst transfer outcomes following intracytoplasmic sperm injection utilizing epididymal versus testicular sperm for men with obstructive azoospermia.All cases at a single center between 2012 and 2016 were included.Operative approach was selected at the surgeon’s discretion and included microepididymal sperm aspiration or testicular sperm extraction.Blastocyst culture was exclusively utilized prior to transfer.The primary outcome was live birth rate.Secondary outcomes included fertilization rate,blastulation rate,euploidy rate,and implantation rate.A mixed effects model was performed.Seventy-six microepididymal sperm aspiration cases and 93 testicular sperm extraction cases were analyzed.The live birth rate was equivalent(48.6%vs 50.5%,P=0.77).However,on mixed effects model,epididymal sperm resulted in a greater likelihood of fertilization(adjusted OR:1.37,95%CI:1.05–1.81,P=0.02)and produced a higher blastulation rate(adjusted OR:1.41,95%CI:1.1–1.85,P=0.01).As a result,the epididymal sperm group had more supernumerary blastocysts available(4.3 vs 3,P<0.05).The euploidy rate was no different.Pregnancy rates were no different through the first transfer cycle.However,intracytoplasmic sperm injection following microepididymal sperm aspiration resulted in a greater number of usable blastocysts per patient.Thus,the true benefit of epididymal sperm may only be demonstrated via a comparison of cumulative pregnancy rates after multiple transfers from one cohort. | Scott J Morin Brent M Hanson Caroline R Juneau Shelby A Neal Jessica N Landis Richard T Scott Jr James M Hotaling | 2020 | Asian Journal of Andrology2020，22，2： | 2 |
| 5 | Clinicopathologic analysis of breast lesions associated with muhiple papillomas 显示文摘 | Ali-Fehmi R Carolin K Wallis T | 2003 | Hum Pathol2003，34，3： | 1 |
| 6 | Biobankonomics: a tax- onomy for evaluating the economic benefits of standardized centralized human biobanking for translational research 显示文摘 | Rogers J Carolin T Vaught J | 2011 | JNCI Monogr2011，42，： | 1 |
| 7 | Biobankonomics: a tox- onomy for evaluating the benefits of standardized centralized hunan biobanking for translation reasearh显示文摘 | Royers J Carolin T Vaught J | 2011 | JNCI Monogr2011，42，： | 1 |
| 8 | Evaluation of morbidity and mortality after anastomotic leakage following elective colorectal surgery in patients treated with or without mechanical bowel preparation显示文摘 | Hans Pieter van’t Sant Wibo F. Weidema Wim C.J. Hop Johan F. Lange Caroline M.E. Contant | 2011 | The American Journal of Surgery2011，，3： | 1 |
| 9 | Relationship marketing in consunmer markets Rhetoric or reality?显示文摘 | LISA O CAROLINE T | 2000 | European Journal d Marketing2000，34，7： | 1 |
| 10 | Dysphagia in Acute stroke显示文摘 | Caroline Gordon Richard Langton Uewer Derick T Ward | 1987 | British Medical Journal1987，295，15： | 1 |
| 11 | Bacterial co- mmunity dynamics in an anaerobic plug-flow type bioreactor treating swine manure 显示文摘 | Caroline S R Guylaine T Edward T | 2009 | Water Res2009，43，1： | 1 |
| 12 | The principal factors affecting construction project overhead expenses:an exploratory factor analysis approach 显示文摘 | Caroline T W Chan | 2012 | Construction Management and Economics2012，30，10： | 1 |
| 13 | Dysphagia in Acute Stroke显示文摘 | Caroline Gord Richard Langton hewer Derick T Wade | 1987 | British Medical Journal1987，295，15： | 1 |
| 14 | Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene显示文摘 | Inge T Caroline M Sven T | 2001 | Biochemical and Biophisical Research Communication2001，287，1： | 1 |
| 15 | Exceptionally high levels of CA125 due to endometriosis显示文摘 | Caroline C Bashir T | 2002 | J Obstet Gynaecol2002，22，3： | 1 |
| 16 | Assessing depression in youth:relation between the Children's Depression Inventory and a structured interview显示文摘 | Benedikte T Caroline B Laura D | 2004 | Journal for Clinical Child and Adoles- cent Psychology2004，33，1： | 1 |
| 17 | The Challenges of Seamless Handover in Future Mobile Multimedia Network显示文摘 | LARRY T RICHARD T CAROLINE L | 1999 | IEEE Personal Communication1999，1999，： | 1 |
| 18 | The influence of mechanical bowel preparation on long-term survival in patients surgically treated for colorectal cancer显示文摘 | Hans Pieter van’t Sant Arnoud Kamman Wim C.J. Hop Martijn van der Heijden Johan F. Lange Caroline M.E. Contant | 2015 | The American Journal of Surgery2015，，1： | 1 |
| 19 | Mechanical bowel preparation for elective colorectal surgery:a multicentre randomised trial 显示文摘 | Caroline ME Contant Wim CJ Hop Hans Pieter van't Sant | 2008 | The Lancet2008，370，9605： | 1 |
| 20 | Dysphagia in Acute Stroke 显示文摘 | Caroline Gordon Richard Langton hewer Derick T Wade | 1987 | British Medical Journal1987，295，15： | 1 |
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