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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Phytoplankton and Zooplankton Response to Ultraviolet Radiation in a High-Altitude Andean Lake:Short-Versus Long-Term Effects显示文摘 | Cabrera S Lopez M Tartarotti B | 1997 | Journal of Plankton Research1997，19，： | 1 |
| 3 | Effects of drying and rewetting on carbon and nitrogen mineralization in soils and incorporated residues显示文摘 | Kruse J S Kissel D E Cabrera M L | 2004 | Nutr Cycl Agroeco- sys2004，69，： | 1 |
| 4 | Extrapolation and spectral estimation with iterative weighted norm modification显示文摘 | Cabrera S D Parks T W | 1991 | IEEE Transactions on Signal Processing1991，9，4： | 1 |
| 5 | Inverse association between serum resistin and insu- lin resistance in humans 显示文摘 | Ominguez Coello S Cabrera de Leon A Atmeida Gonzalez D | 2008 | Diabetes Res Clin Pract2008，82，2： | 1 |
| 6 | Learning technique to train neural networks as a state selector for inverter-fed induction machines using direct torque control 显示文摘 | Cabrera L A Elbuluk M E Zinger D S | 1997 | IEEE Trans on PE1997，12，5： | 1 |
| 7 | Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly (dimethylsiloxane) devices 显示文摘 | HEO Y S CABRERA L M SONG J W | 2007 | Anal Chem2007，79，3： | 1 |
| 8 | Fathers and mothers at play with their 2 - and 3 - year- olds: contributions to language and cognitive development 显示文摘 | TAMIS- LEMONDA C S SHANNON J D CABRERA N J | 2004 | Child Dev2004，75，6： | 1 |
| 9 | Molecular markers of endometrial carcinoma detected in uterine aspirates显示文摘 | COLAS E PEREZ C CABRERA S | 2011 | Inter- national Journal of Cancer2011，129，10： | 1 |
| 10 | The treat- ment of open tibial fractures and of tibial non - union with a novel external fixator 显示文摘 | Ong C T Choon D S K Cabrera N P | 2002 | Injur2002，33，9： | 1 |
| 11 | The oxidant/antioxidant network: Role of melatonin 显示文摘 | Tan DX Cabrera J D'Apra D Sainz RM Mayo JC Ramos S | 1999 | Biol Signals Recept1999，8，12： | 1 |
| 12 | The role of ion channels in hypoxic pulmonary vasoconstriction 显示文摘 | Weir EK Cabrera JA Mahapatra S | 2010 | Adv Exp Med Biol2010，661，： | 1 |
| 13 | Architecture of the pulmonary veins:relevance to radiofrequency ablation显示文摘 | Ho S Y Cabrera J A Tran V H | | 0，，03： | 1 |
| 14 | Genetic Polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) Genes Associated With Pathological Characteristics of Prostate Cancer in the Ecuadorian Population显示文摘 | Andrés López-Cortés Gabriela Jaramillo-Koupermann María J. Mu?oz Alejandro Cabrera Carolina Echeverría Felipe Rosales Nicolás Vivar César Paz-y-Mi?o | 2013 | The American Journal of the Medical Sciences2013，，： | 1 |
| 15 | Chelating action of thioglycollic acid with silver and some common bilvalent cation 显示文摘 | Cabrera A M West T S | 1962 | Talanta1962，9，8： | 1 |
| 16 | Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos显示文摘 | WLODARCZYK B J CABRERA R M HILL D S | 2006 | Neurotoxicology2006，27，： | 1 |
| 17 | Exploratory Dijkstra forest based automatic vessel seg- mentation : applications in video indirect ophthalmoscopy (VIO) 显示文摘 | Estrada R Tomasi C Cabrera MT Wallace DK Freedman SF Farsiu S | 2012 | Biomedical Optics Express2012，3，2： | 1 |
| 18 | Oxidation of methanol on platinum, ruthenium and mixed Pt-M metais (M = Ru, Sn) : A theoretical study显示文摘 | ISHIKAWA Y LIAO M S CABRERA C R | 2000 | Surf Sci2000，463，1： | 1 |
| 19 | Dietary fiber and lifestyle influence serum lipids in free living adult men显示文摘 | BALLESTEROS M N CABRERA R M SAUCEDO M S | 2001 | J Am Coll Nutr2001，20，： | 1 |
| 20 | Design, manufacture and testing of a new hybrid column显示文摘 | Mirmiran A Samaan M Cabrera S | 1998 | Construction and building materials1998，12，1： | 1 |
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