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50篇 您的检索式:作者名="Burakoff"
    题名 作者 年代 出处 被引量
1Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58显示文摘Hahn WC Burakoff SJ Bierer BE 1993J Immunol1993,150,7:1
2Targeting Src homology 2 do-main-containing tyrosine phosphatic (SHP-1) into lipid rafts inhibits CD3-induced T cell activation显示文摘Su MW Yu CL Burakoff SJ 2001J Immunol2001,166,6:1
3Lymphoid irradiation results in long-time increase in natural killer cells in patients treated for Hodgkin's disease 显示文摘Macklis R M Manch P M Burakoff S J 1992Cancer1992,69,3:1
4Extraintestinal manifestations of inflammatory bowel disease显示文摘Levine JS Burakoff R 2011Gastroenterol Hepatol2011,7,4:1
5Use of blood based biomarkers in the evaluation of Crohn's disease and ulcerative colitis显示文摘Despite significant improvements in our understanding of Crohn's disease(CD) and ulcerative colitis(UC) in recent years, questions remain regarding the best approaches to assessment and management of these chronic diseases during periods of both relapse and remission. Various serologic biomarkers have been used in the evaluation of patients with both suspected and documented inflammatory bowel disease(IBD), and while each has potential utility in the assessment of patients with IBD, potential limitation remain with each method of assessment. Given these potential shortcomings, there has been increased interest in other means of evaluation of patients with IBD, including an expanding interest in the role of gene expression profiling. Among patients with IBD, gene expression profiles obtained from whole blood have been used to differentiate active from inactive CD, as well as to differentiate between CD, UC, and non-inflammatory diarrheal conditions. There are many opportunities for a non-invasive, blood based test to aid in the assessment of patients with IBD, particularly when considering more invasive means of evaluation including endoscopy with biopsy. Furthermore, as the emphasis on personalized medicine continues to increase, the potential ability of gene expression analysis to predict patient response to individual therapies offers great promise. While whole blood gene expression analysis may not completely replace more traditional means of evaluating patients with suspected or known IBD, it does offer significant potential to expand our knowledge of the underlying genes involved in the development of these diseases.Edward L Barnes Choong-Chin Liew Samuel Chao Robert Burakoff 2015World Journal of Gastrointestinal Endoscopy2015,7,17:1
6The irritable bowel syndrome and food hypersensitivity显示文摘Zwetchkenbaum J Burakoff F 1988Ann Allergy1988,6,1:1
7Pregnancy and nursing显示文摘Burakoff R Opper F 1995Gastroenterol Clin North Am1995,24,:1
8Uncoupling p70 (s6) kinase activation and proliferation:rapamycin-resistant proliferation of human CD8+T lymphocytes显示文摘Slavik J Lim D Burakoff J 2001J Immunol2001,166,5:1
9The role of mesalaminc in the treatment of ulcerative colitis显示文摘Karagozian R Burakoff R 2007Ther Clin Risk Manag2007,3,5:1
10The effect of the immunosuppresant FK-506 on alternate pathways of T cell activation显示文摘BIERER BE SCHREIBER SL BURAKOFF SJ 1991Eur J Immunol1991,21,2:1
11Cytosolic tyrosine dephosphorylation of TAT5:Potential role of SHP-2 in STAT5 regulation显示文摘Yu CL Jin YJ Burakoff SJ 2000J Biol Chem2000,275,1:1
12Wnt-1 and wnt-4 regulate thymic cellularity显示文摘Mulroy T McMahon J A Burakoff S J 2002Eur J Immunol2002,32,4:1
13Pregnancy and nursing显示文摘Burakoff R1 Opper F 1995Gastroenterol Clin North Am1995,24,3:1
14Molecular cloning of a 25-kDahigh affinity ? rapamycin binding protein,FKBP25 显示文摘Jin Y J Burakoff S J Bierer B E 1992J BiolChem1992,267,10:1
15Constitutive activation of the Janus kinase-STAT pathway in T lymphoma overexpressing the lck protein tyrosine kinase显示文摘Yu CL Jove R Burakoff SJ 1997J Immunol1997,159,:1
16The 25-kDa FK506-binding protein is local-ized in the nucleus and associates with casein kinase D and nucle-olin显示文摘Jin Y J Burakoff S J 1993Proc Natl Acad Sci USA1993,90,16:1
17The human HLA specific monoclonal antibody W6/32 recognizes a discontinuous epitope within the α2 domain of murine H-2Db显示文摘Dr. Richard T. Maziarz John Fraser Jack L. Strominger Steven J. Burakoff 1986Immunogenetics1986,,3:1
18显示文摘Su MW Yu CL Burakoff SJ 2001J Immunol2001,166,:1
19A phase 1/2A trial of STA 5326,an oral interleukin-12/23 inhibitor,in patients with active moderate to severe Crohn's disease显示文摘Burakoff R Barish CF Riff D 0,,:1
20Cytolytic pathways in haematopoietic stem-cell transplantation显示文摘van den Brink MR Burakoff SJ 2002Nat Rev Immunol2002,2,4:1
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