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| 1 | A simple scoring system to estimate perioperative mortality following liver resection for primary liver malignancy-the Hepatectomy Risk Score(HeRS)显示文摘Background:Selection of the optimal treatment modality for primary liver cancers remains complex,balancing patient condition,liver function,and extent of disease.In individuals with preserved liver function,liver resection remains the primary approach for treatment with curative intent but may be associated with significant mortality.The purpose of this study was to establish a simple scoring system based on Model for End-stage Liver Disease(MELD)and extent of resection to guide risk assessment for liver resections.Methods:The 2005-2015 NSQIP database was queried for patients undergoing liver resection for primary liver malignancy.We first developed a model that incorporated the extent of resection(1 point for major hepatectomy)and a MELD-Na score category of low(MELD-Na=6,1 point),medium(MELD-Na=7-10,2 points)or high(MELD-Na>10,3 points)with a score range of 1-4,called the Hepatic Resection Risk Score(HeRS).We tested the predictive value of this model on the dataset using logistic regression.We next developed an optimal multivariable model using backwards sequential selection of variables under logistic regression.We performed K-fold cross validation on both models.Receiver operating characteristics were plotted and the optimal sensitivity and specificity for each model were calculated to obtain positive and negative predictive values.Results:A total of 4,510 patients were included.HeRS was associated with increased odds of 30-day mortality[HeRS=2:OR=3.23(1.16-8.99),P=0.025;HeRS=3:OR=6.54(2.39-17.90),P<0.001;HeRS=4:OR=13.69(4.90-38.22),P<0.001].The AUC for this model was 0.66.The AUC for the optimal multivariable model was higher at 0.76.Under K-fold cross validation,the positive predictive value(PPV)and negative predictive value(NPV)of these two models were similar at PPV=6.4%and NPV=97.7%for the HeRS only model and PPV=8.4%and NPV=98.1%for the optimal multivariable model.Conclusions:The HeRS offers a simple heuristic for estimating 30-day mortality after resection of primary liver malignancy.More complicated models offer better performance but at the expense of being more difficult to integrate into clinical practice. | Dimitrios Moris Brian I.Shaw Cecilia Ong Ashton Connor Mariya L.Samoylova Samuel J.Kesseli Nader Abraham Jared Gloria Robin Schmitz Zachary W.Fitch Bryan M.Clary Andrew S.Barbas | 2021 | Hepatobiliary Surgery and Nutrition2021，10，3： | 2 |
| 2 | BIOGENIC MANGANESE OXIDES: Properties and Mechanisms of Formation显示文摘 | Bradley M. Tebo John R. Bargar Brian G. Clement Gregory J. Dick Karen J. Murray Dorothy Parker Rebecca Verity Samuel M. Webb | 2004 | Annual Review of Earth and Planetary Sciences2004，，： | 2 |
| 3 | A comparison of detection per formance for several track-before detect algorithms显示文摘 | Samuel J D Mark G R Brian C | 2008 | Journal on Advances in Signal Processing2008，，： | 1 |
| 4 | A Randomized Trial of Pelvic Radiation Therapy versus No Further Therapy in Selected Patients with Stage IB Carcinoma of the Cervix after Radical Hysterectomy and Pelvic Lymphadenectomy: A Gynecologic Oncology Group Study显示文摘 | Alexander Sedlis Brian N. Bundy Marvin Z. Rotman Samuel S. Lentz Laila I. Muderspach Richard J. Zaino | 1999 | Gynecologic Oncology1999，，2： | 1 |
| 5 | Percutaneous nephrolithotomy for ectopic kidneys: Over, around, or through显示文摘 | Brian R. Matlaga Samuel C. Kim Stephanie L. Watkins Ramsay L. Kuo Larry C. Munch James E. Lingeman | 2006 | Urology2006，，3： | 1 |
| 6 | Prognostic value of Kit mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors显示文摘 | Samuel S Brian PR Marcia LL | 2002 | J Clin Oncol2002，20，： | 1 |
| 7 | Nonlinear dynamics for broadband energy harvesting: Investigation of a bistable piezoelectric inertial generator显示文摘 | Samuel C. Stanton Clark C. McGehee Brian P. Mann | 2010 | Physica D: Nonlinear Phenomena2010，，10： | 1 |
| 8 | A Comparison of Postoperative Pain Control in Patients After Right Lobe Donor Hepatectomy and Major Hepatic Resection for Tumor显示文摘 | Jacek B. Cywinski Brian M. Parker Meng Xu Samuel A. Irefin | 2004 | Anesthesia & Analgesia2004，，6： | 1 |
| 9 | Multicenter phase II trialof ABI - 007,an albumin - bound paclitaxel, in women with meta-static breast cancer显示文摘 | Nuhad K Ibrahim Brian Samuels | 2005 | J Clin Oncol2005，23，： | 1 |
| 10 | Laparoscopic Transumbilical Cholecystectomy Without Visible Abdominal Scars显示文摘 | Ninh T. Nguyen Kevin M. Reavis Marcelo W. Hinojosa Brian R. Smith Samuel E. Wilson | 2009 | Journal of Gastrointestinal Surgery2009，，6： | 1 |
| 11 | Analyzing the representative- ness of intemet political participation 显示文摘 | SAMUEL J B BRIAN S K | 2005 | Political Be- havior2005，27，2： | 1 |
| 12 | Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence显示文摘 | Jorge D. Reyes Brian Carr Igor Dvorchik Samuel Kocoshis Ronald Jaffe David Gerber George V. Mazariegos Javier Bueno Rick Selby | 2000 | The Journal of Pediatrics2000，，6： | 1 |
| 13 | A Comparison of Detection Performance for Several Track-before-detect Al- gorithms显示文摘 | SAMUEL J D MARK G R BRIAN C | 2007 | EURASIP Journal on Advances in Signal Processing2007，，： | 1 |
| 14 | School Climate and Teachers' Beliefs and Attitudes Associated with Implementation of the Positive Action Pro- gram: A Diffusion of Innovations Model显示文摘 | MICHAEL W BEETS BRIAN R FLAY SAMUEL VUCH INICH | 2008 | Prevention Sci- ence2008，9，26： | 1 |
| 15 | Dysregulation of Protein Kinase A Signaling in the Aged Prefrontal Cortex显示文摘 | Brian P. Ramos Shari G. Birnbaum Isabelle Lindenmayer Samuel S. Newton Ronald S. Duman Amy F.T. Arnsten | 2003 | Neuron2003，，4： | 1 |
| 16 | Analyzing the representativeness of internet political participation显示文摘 | Samuel J. Best Brian S. Krueger | 2005 | Political Behavior2005，，2： | 1 |
| 17 | Prospective Multicenter Study of Pregnancy Outcomes in Women With Heart Disease显示文摘 | Samuel C. Siu Mathew Sermer Jack M. Colman A. Nanette Alvarez Lise-Andree Mercier Brian C. Morton Catherine M. Kells M. Lynn Bergin Marla C. Kiess Francois Marcotte Dylan A. Taylor Elaine P. Gordon John C. Spears James W. Tam Kofi S. Amankwah Jeffrey F. S | 2001 | Circulation: Journal of the American Heart Association2001，，5： | 1 |
| 18 | A Randomized Trial of Pelvic Radiation Therapy versus No Further Therapy in Selected Patients with Stage IB Carcinoma of the Cervix after Radical Hysterectomy and Pelvic Lymphadenectomy: A Gynecologic Oncology Group Study显示文摘 | Alexander Sedlis Brian N. Bundy Marvin Z. Rotman Samuel S. Lentz Laila I. Muderspach Richard J. Zaino | 1999 | Gynecologic Oncology1999，，2： | 1 |
| 19 | Evaluation of Comprehensive Treatment Models for Individuals with Autism Spectrum Disorders 显示文摘 | Samuel L Odom Brian A Boyd | 2010 | Journal of antism and developmental disorders2010，40，4： | 1 |
| 20 | Anatomic Segmentectomy in the Treatment of Stage I Non-Small Cell Lung Cancer显示文摘 | Matthew J. Schuchert Brian L. Pettiford Samuel Keeley Thomas A. D’Amato Arman Kilic John Close Arjun Pennathur Ricardo Santos Hiran C. Fernando James R. Landreneau James D. Luketich Rodney J. Landreneau | 2007 | The Annals of Thoracic Surgery2007，，3： | 1 |
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