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| 1 | Right ventricular septal pacing: Safety and efficacy in a long term follow up显示文摘AIM: To evaluate the safety and efficacy of the permanent high interventricular septal pacing in a long term follow up, as alternative to right ventricular apical pacing. METHODS: We retrospectively evaluated:(1) 244 patients(74 ± 8 years; 169 men, 75 women) implanted with a single(132 pts) or dual chamber(112 pts) pacemaker(PM) with ventricular screw-in lead placed at the right ventricular high septal parahisian site(SEPTAL pacing);(2) 22 patients with permanent pacemaker and low percentage of pacing(< 20%)(NO pacing);(3) 33 patients with high percentage(> 80%) right ventricular apical pacing(RVA). All patients had a narrow spontaneous QRS(101 ± 14 ms). We evaluated New York Heart Association(NYHA) class, quality of life(Qo L), 6 min walking test(6MWT) and left ventricular function(end-diastolic volume, LV-EDV; end-systolic volume, LVESV; ejection fraction, LV-EF) with 2D-echocardiography. RESULTS: Pacing parameters were stable duringfollow up(21 mo/patient). In SEPTAL pacing group we observed an improvement in NYHA class, Qo L score and 6MWT. While LV-EDV didn't significantly increase(104 ± 40 m L vs 100 ± 37 m L; P = 0.35), LV-ESV slightly increased(55 ± 31 m L vs 49 ± 27 m L; P = 0.05) and LV-EF slightly decreased(49% ± 11% vs 53% ± 11%; P = 0.001) but never falling < 45%. In the RVA pacing control group we observed a worsening of NYHA class and an important reduction of LV-EF(from 56% ± 6% to 43% ± 9%, P < 0.0001).CONCLUSION: Right ventricular permanent high septal pacing is safe and effective in a long term follow up evaluation; it could be a good alternative to the conventional RVA pacing in order to avoid its deleterious effects. | Eraldo Occhetta Gianluca Quirino Lara Baduena Rosaria Nappo Chiara Cavallino Emanuela Facchini Paolo Pistelli Andrea Magnani Miriam Bortnik Gabriella Francalacci Gabriele Dell’Era Laura Plebani Paolo Marino | 2015 | World Journal of Cardiology2015，7，8： | 5 |
| 2 | Future easy and physiological cardiac pacing显示文摘The right atrial appendage (RAA) and right ventricular apex (RVA) have been widely considered as conventional sites for typical dual-chamber atrio-ventricular cardiac (DDD) pacing. Unfortunately conventional RAA pacing seems not to be able to prevent atrial fibrillation in DDD pacing for tachycardia-bradycardia syndrome, and the presence of a left bundle branch type of activation induced by RVA pacing can have negative effects. A new technology with active screw-in leads permits a more physiological atrial and right ventricular pacing. In this review, we highlight the positive effects of pacing of these new and easily selected sites. The septal atrial lead permits a shorter and more homogeneous atrial activation, allowing better prevention of paroxysmal atrial fibrillation. The para-Hisian pacing can be achieved in a simpler and more reliable way with respect to biventricular pacing and direct Hisian pacing. We await larger trials to consider this 'easy and physiological pacing' as a first approach in patients who need a high frequency of pacing. | Eraldo Occhetta Miriam Bortnik Paolo Marino | 2011 | World Journal of Cardiology2011，3，1： | 5 |
| 3 | Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and-resistant triple- negative breast cancer 显示文摘 | Chittaranjan S Bortnik S Dragowska WH | 2014 | Clin Cancer Res2014，20，12： | 1 |
| 4 | Prevention of ventricular desynchronization by permanent para-hisian pacing after atrioventricular node ablation in chronic atrial fibrillation 显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Clil Cardiol2006，47，： | 1 |
| 5 | Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation:a crossover,blinded,randomized study versus apical right ventricular pacing显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Coll Cardiol2006，47，10： | 1 |
| 6 | Ventricular fibrillation in acute mitral valve insufficiency caused by chordae tendineae rupture: report of a surgically corrected case显示文摘 | Bortnik M Leverone M Teodofi G | 2009 | J Cardiovasc Med (Hagersto- wn)2009，10，3： | 1 |
| 7 | Analyzing a X model of a turntable system using spin, CADP and up- paal显示文摘 | BORTNIK E TRICKA N WIJS A J et ai | 2005 | Journal of Logic and Algebraic Programming2005，65，2： | 1 |
| 8 | Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation:a crossover,blinded,randomized study versus apical right ventricular pacing显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Coll Cardiol2006，47，10： | 1 |
| 9 | Electrical breakdown and the similarity law in SF6 AT extra-high-voltages显示文摘 | Bortnik Ivan M Cooke Chathan M | | 0，，05： | 1 |
| 10 | The DDDR closed loop stimulation for the prevention of vasovagal syncope:resuhs from the INVAY prospective feasibility registry显示文摘 | Oechetta E Bortnik M Vassanelli C | 2003 | Europace2003，5，： | 1 |
| 11 | Permanent parahisian pa- cing显示文摘 | Occhetta E Bortnik M Marino P | 2007 | Indian Pacing Electrophysiol J2007，7，2： | 1 |
| 12 | Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation:A crossover, blinded,randomized study versus apical right ventricular pacing显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Coll Cardiol2006，47，10： | 1 |
| 13 | Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioven- tricular node ablation in chronic atrial fibrillation: a crossover, blin- ded, randomized study versus apical right ventricular pacing 显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Coil Cardiol2006，47，10： | 1 |
| 14 | Permanent parahisian pacing显示文摘 | Occhetta E Bortnik M Marian P | 2007 | Indian Pacing Electrophysiol J2007，7，2： | 1 |
| 15 | Permanent parahisian pacing显示文摘 | Occhet a E Bortnik M Marino P | | 0，，02： | 1 |
| 16 | Electrical Breakdown and the Similarity Law in SF6 at Extra-high-voltages显示文摘 | Bortnik I M Cooke C M | 1972 | IEEE Trans- actions on Power Apparatus and Systems1972，91，5： | 1 |
| 17 | Dynamic- range enhancement and linearizatlon in electro-optically modulated coherent optical link显示文摘 | HUNGY C BORTNIK B FETTERMAN H R | 2007 | Journal of Lightwave Technology2007，28，1： | 1 |
| 18 | Permanent parahisan pacing 显示文摘 | Occhetta E Bortnik M Marino P | 2007 | Indian Pacing Electrophysiol J2007，7，2： | 1 |
| 19 | Prevention of ventricular desynchronization by permanent para-Hisian pacing after atrioventricular node ablation in chronic atrial fibrillation : a crossover, blinded, randomized study versus apical right ventricular pacing显示文摘 | Occhetta E Bortnik M Magnani A | 2006 | J Am Coll Cardiol2006，47，： | 1 |
| 20 | Prevention of Ventricular Desynchronization by Permanent Para-Hisian Pacing After Atrioventricular Node Ablation in Chronic Atrial Fibrillation显示文摘 | Eraldo Occhetta Miriam Bortnik Andrea Magnani Gabriella Francalacci Cristina Piccinino Laura Plebani Paolo Marino | 2006 | Journal of the American College of Cardiology2006，，10： | 1 |
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