|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 高级别胶质瘤放、化疗耐药性可能与microRNAs相关(英文)显示文摘High-grade gliomas(HGGs) are malignant primary brain tumors of glial cell origin.Despite optimal course of treatment,including maximal surgical resection followed by adjuvant chemo-and/or radiotherapy,the prognosis still remains poor.The main reason is the commonly occurring chemo-and radioresistance of these tumors.In recent years,several signaling pathways,especially PI3K/AKT and ATM/CHK2/p53,have been linked to the resistance of gliomas.Moreover,additional studies have shown that these pathways are significantly regulated by microRNAs(miRNAs),short endogenous RNA molecules that modulate gene expression and control many biological processes including apoptosis,proliferation,cell cycle,invasivity,and angiogenesis.MiRNAs are not only highly deregulated in gliomas,their expression signatures have also been shown to predict prognosis and therapy response.Therefore,they present promising biomarkers and therapeutic targets that might overcome the resistance to treatment and improve prognosis of glioma patients.In this review,we summarize the current knowledge of the functional role of miRNAs in gliomas resistance to chemo-and radiotherapy. | Besse A Sana J Fadrus P Slaby O | 2013 | 中华神经外科疾病研究杂志2013，12，2： | 3 |
| 2 | Barriers to health care among people with disa- bilities who are members of underserved racial/ethnic groups : a scoping review of the literature 显示文摘 | PETERSON - BESSE J J WAKSH E S HORNER - JOHN- SON W | 2014 | Med Care2014，52，3： | 1 |
| 3 | Three distinct types of hotspots in the Earth's mantle显示文摘 | Courtillot V Davaille A Besse J | 2003 | Earth and Planetary Science Letters2003，205，： | 1 |
| 4 | The Motivation to Teach显示文摘 | Bess J | | 0，，48： | 1 |
| 5 | Effect of orogeny,plate motion and land-sea distribution on Eurasian climate change over the past 30 million years显示文摘 | FLUTEAU F BESSE J | 1997 | Nature1997，386，： | 1 |
| 6 | The evolving role of histology in the management of advanced non-small-cell lung cancer 显示文摘 | Langer C J Besse B Gualberto A | 2010 | J Clin Oncol2010，28，36： | 1 |
| 7 | Children with minimal sensorineural hearing loss; prevalence,educational performance,and functional status显示文摘 | Bess FH Dodd-Mophy J Parker RA | 1998 | Ear Hear1998，19，5： | 1 |
| 8 | 'Crochetage' ( Notch ) on wave in inferior limb leads: A new independt electrocadiographic sign of atrial septal defect显示文摘 | Heller J Hagege AA Besse B | 1996 | JACC1996，27，4： | 1 |
| 9 | 3xP3-EGFP maker facilitates screening for transgenic silkworm Bombyx moriL, from the embryonic stage onwards 显示文摘 | THOMAS J L DA ROCHA M BESSE A | 2002 | Insect Biochemistry and Molecular Biology2002，32，： | 1 |
| 10 | Polymer interleaved layered double hydroxide: A new emerging class of nanocomposites 显示文摘 | Leroux F Besse J P | 2001 | Chemistry of Materials2001，13，： | 1 |
| 11 | Comparison of screening methods in the detection of bladder cancer显示文摘 | Ramakumar S Bhuiyan J Besse J A | 1999 | J Urol1999，161，： | 1 |
| 12 | Combined paleomagnetic and isotopic data from the Doushantuo carbonate, South China: implication for the ' snowball Earth' hypothesis显示文摘 | MACOUIN M BESSE J ADER M GILDER S YANG Z SUN Z AGRINIER P | 2004 | Earth and Planetary Science Letters2004，224，： | 1 |
| 13 | Neratinib,an irreversible pan-Erb B receptor tyrosine kinase inhibitor;Result of a phaseⅡtrial in patients with advanced non-small-cell lung cancer显示文摘 | Sequist L V Besse B Lynch T J | 2010 | J Clin Oncol2010，28，18： | 1 |
| 14 | Comparison of screening methods in the detection of bladder cancer显示文摘 | Ramakumar S Bhuiyan J Besse JA | | 0，，： | 1 |
| 15 | Synthesis of Al-rich hydrotalcite - like compounds by using the urea hydrolysis reaction -control of size and morphology 显示文摘 | Adachi-pagano M Forano C Besse J | 2003 | Mater Chem2003，13，： | 1 |
| 16 | The future of magnetic sensors 显示文摘 | Popovie R S Flanagan J A Besse P A | 1996 | Sensors Actuators A1996，56，： | 1 |
| 17 | Paleogeographlc maps of the continents bordering the Indian Ocean since the Early Jurassic显示文摘 | Besse J Courtillot V | 1988 | Journal of Geophysi- cal Research1988，93，11： | 1 |
| 18 | Photometric correction and inflight calibration of Chang’E-1Interference Imaging Spectrometer(IIM)data显示文摘 | Wu Y Besse S Li J | 2013 | Icarus2013，222，1： | 1 |
| 19 | Three distinct types of hotspots in the Earth' s mantle显示文摘 | Courtillot V Davaille A Besse J | 2003 | Earth and Planetary Science Letters2003，205，3： | 1 |
| 20 | Delamination of layered double hydroxides by use of surfactants显示文摘 | Adaehi-Pagano M Forano C Besse J P | 2000 | Chem Commun2000，9192，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员