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| 1 | 肝癌发生过程中转录因子AP-1活化的研究显示文摘目的:检测肝癌及其癌周组织中AP-1活化状态,探索该转录因子在肝癌发生过程中可能的作用。方法:用电泳迁移率转移试验、免疫印迹和RNA酶保护性分析等方法,测定15例原发性肝癌及其癌周组织中AP-1与DNA的结合活性、AP-1复合物的蛋白组成以及细胞增殖状况。结果:与正常肝组织相比,AP-1与DNA结合活性在73%的癌周组织中增高;60%的肝癌组织中AP-1结合活性比癌周组织进一步增高;其AP-1二聚体主要由JunD、c-Jun和c-Fos蛋白参与组成,AP-1结合活性与JunD和c-Jun蛋白表达水平呈正相关。结论:AP-1的激活是肝癌发生过程中的早期频发事件,可能有助于肝细胞恶性转化表型的获得,在肝癌的形成中具有重要作用。 | 刘平 Bernau Dominique | 2004 | 南京医科大学学报(自然科学版)2004，24，1： | 5 |
| 2 | Teacher Motivation Strategies,Student Perceptions,Student Motivation,and English Achievement显示文摘 | Bernaus M Gardner R | | 0，，92： | 1 |
| 3 | Solder doped polycaprolactone scaffold enables reproducible laser tissue soldering 显示文摘 | Bregy A Bogni S Bernau VJ | 2008 | Lasers Surg Med2008，40，10： | 1 |
| 4 | Recommendations of the International Association for the Study of the Liver Subcommittee on nomenclature of acute and subacute liver failure 显示文摘 | TANDON B BERNAU AU J O'GRADY J | 1999 | J Gastroenterol Hepatol1999，14，： | 1 |
| 5 | Myofibroblasts exhibit enhancedfibronectin assembly that is intrinsic to their contractilephenotype显示文摘 | Torr EE Ngam CR Bernau K | 2015 | J Biol Chem2015，290，11： | 1 |
| 6 | Almost f-algebra and d-algebra显示文摘 | Bernau S J Huijsmans C B | 1990 | Math Proc Cambridge Phil Soc1990，107，： | 1 |
| 7 | The Order Bidual of Almost f-algebra and d-algebra 显示文摘 | Bernau S J Huijsmans C B | 1995 | Transactions of the American Mathematical Society1995，347，： | 1 |
| 8 | Almost f-algebra and d-algebra 显示文摘 | Bernau S J Huijsmans C B | 1990 | Mathematical Proceedings of Cambrige Philosophical Socirty1990，107，： | 1 |
| 9 | Affective Factors Influencing Plurilingual Students’ Acquisition of Catalan in a Catalan–Spanish Bilingual Context显示文摘 | MERCèBERNAUS EMILEEMOORE ADRIANA CORDEIROAZEVEDO | 2007 | The Modern Language Journal2007，，2： | 1 |
| 10 | Determination of mercury in polluted soils surrounding a chlor alkali plant Direct speciation by X-ray absorption speetros copy techniques and preliminary geochemical characterisa tion of the area显示文摘 | Anna Bernaus Xavier Gaona Derk van Ree | 2006 | Analytica Chimica Aeta2006，565，： | 1 |
| 11 | Analysis of sorption and bioavailability of different species of mercury on model soil components using XAS techniques and sensor bacteria显示文摘 | Anna Bernaus Xavier Gaona Angela Ivask Anne Kahru Manuel Valiente | 2005 | Analytical and Bioanalytical Chemistry2005，，7： | 1 |
| 12 | Teacher Motivation Strategies, Student Perceptions, Student Motivation, and English Achievement显示文摘 | MERCèBERNAUS ROBERT C.GARDNER | 2008 | The Modern Language Journal2008，，3： | 1 |
| 13 | Orthomorphisms of Archimedean vector lattices显示文摘 | Bernau S J | 1981 | Mathematical Proceedings of Cambridge Philosophical Society1981，89，： | 1 |
| 14 | Carinoeonus iraqiensis (Foraminifera) , a new orbitolinid from the Cenomanian Mishrif Formation of the oil fields of southeastern Iraq 显示文摘 | Bernaus J M Masse P | 2006 | Mieropaleontology2006，52，5： | 1 |
| 15 | Intra-articular sodium hyaluronate in osteoarthritis of the knee: a muhicenter, double-blind study 显示文摘 | Puhl W Bernau A Greiling H | 1993 | Osteoarthritis Cartilage1993，1，4： | 1 |
| 16 | Improved strat- egy for phylogenetic analysis of classical swine fever virus based on full-length E2 encoding sequences显示文摘 | Postel A Schmeiser S Bernau J | 2012 | Vet Res2012，43，： | 1 |
| 17 | Reducing bacterial adhesion to titanium surfaces using low intensity alternating electrical pulses显示文摘BACKGROUND Orthopedic implant-related infection remains one of the most serious complications after orthopedic surgery.In recent years,there has been an increased scientific interest to improve prevention and treatment strategies.However,many of these strategies have focused on chemical measures.AIM To analyze the effect of alternating current electrical fields on bacterial adherence to titanium surfaces.METHODS Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli)were exposed to 6.5 V electrical currents at different frequencies:0.5 Hz,0.1 Hz,and 0.05 Hz.After exposure,a bacterial count was then performed and compared to the control model.Other variables registered included the presence of electrocoagulation of the medium,electrode oxidation and/or corrosion,and changes in pH of the medium.RESULTS The most effective electrical model for reducing S.aureus adhesion was 6.5 V alternating current at 0.05 Hz achieving a 90%adhesion reduction rate.For E.coli,the 0.05 Hz frequency model also showed the most effective results with a 53%adhesion reduction rate,although these were significantly lower than S.aureus.Notable adhesion reduction rates were observed for S.aureus and E.coli in the studied conditions.However,the presence of electrode oxidation makes us presume these conditions are not optimal for in vivo use.CONCLUSION Although our findings suggest electrical currents may be useful in preventing bacterial adhesion to metal surfaces,further research using other electrical conditions must be examined to consider their use for in vivo trials. | Marti Bernaus Jordi Guillem-Marti Adrian Bermúdez-Castel Jose Antonio Calero Diego Torres Margarita Veloso Lluís Font-Vizcarra | 2022 | World Journal of Orthopedics2022，13，6： | 0 |
| 18 | Role of joint aspiration before re-implantation in patients with a cement spacer in place显示文摘BACKGROUND The usefulness of a mandatory joint aspiration before re-implantation in patients with a cement spacer already in place is unclear.AIM To evaluate the role of culturing synovial fluid obtained by joint aspiration before re-implantation in patients who underwent a two-stage septic revision.METHODS A retrospective observational study was conducted,including patients that underwent a two-stage septic revision(hip or knee)from 2010 to 2017.After the first stage revision and according to intraoperative culture results,all patients were treated with an antibiotic protocol for 6-8 wk.Following 2 wk without antibiotics,a culture of synovial fluid was obtained.The results of these cultures were recorded and compared with cultures obtained during re-implantation surgery.RESULTS Forty-one patients(20 hip and 21 knee spacers)were included in the final analysis.In 39 cases,the culture of synovial fluid was negative,while in the remaining 2 cases(knee spacers)no analysis was possible due to dry tap.In 5 of the patients,two or more intraoperative cultures taken during the re-implantation surgery were positive.CONCLUSION We found no evidence to support mandatory joint aspiration before re-implantation in patients with a cement spacer in place. | Sandra Huguet MartíBernaus Lucía Gómez Eva Cuchí Alex Soriano Lluís Font-Vizcarra | 2022 | World Journal of Orthopedics2022，13，6： | 0 |
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