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| 1 | Sclerosing cholangitis following severe trauma: Description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms显示文摘AIM: Persistent cholestasis is a rare complication of severe trauma or infections, Little is known about the possible pathomechanisms and the clinical course,METHODS: Secondary sclerosing cholangitis was diagnosed in five patients with persistent jaundice after severe trauma (one burn injury, three accidents, one power current injury). Medical charts were retrospectively reviewed with regard to possible trigger mechanisms for cholestasis, and the clinical course was recorded.RESULTS: Diagnosis of secondary sclerosing cholangitis was based in all patients on the primary sclerosing cholangitis (PSC)-like destruction of the intrahepatic bile ducts at cholangiography after exclusion of PSC. In four patients, arterial hypotension with subsequent ischemia may have caused the bile duct damage, whereas in the case of power current injury direct thermal damage was assumed to be the trigger mechanism. The course of secondary liver fibrosis was rapidly progressive and proceeded to liver cirrhosis in all four patients with a follow-up >2 years. Therapeutic possibilities were limited.CONCLUSION: Posttraumatic sclerosing cholangitis is a rare but rapidly progressive disease, probably caused by ischemia of the intrahepatic bile ducts via the peribiliary capillary plexus due to arterial hypotension. Gastroenterologists should be aware of this disease in patients with persistent cholestasis after severe trauma. | Johannes Benninger Rainer Grobholz Yurdaguel Oeztuerk Christoph H.Antoni Eckhart G.Hahn Manfred V.Singer Richard Strauss | 2005 | World Journal of Gastroenterology2005，11，27： | 10 |
| 2 | Pancreatic duct stones in chronic pancreatitis: Criteria for treatment intensity and success显示文摘 | Michael J. Farnbacher Christoph Schoen Thomas Rabenstein Johannes Benninger Eckhart G. Hahn H.Thomas Schneider | 2002 | Gastrointestinal Endoscopy2002，，4： | 2 |
| 3 | Mucosal regeneration of maxillary sinus after surgery显示文摘 | Benninger MS Sebek BA Levine HL | 1989 | Otolaryngol Head Neck Surg1989，101，33： | 1 |
| 4 | Association Between Human Immunodeficiency Virus Infection and Stiffness of the Common Carotid Artery显示文摘 | Eric C. Seaberg Lorie Benning A. Richey Sharrett Jason M. Lazar Howard N. Hodis Wendy J. Mack Mark J. Siedner John P. Phair Lawrence A. Kingsley Robert C. Kaplan | 2010 | Stroke2010，，10： | 1 |
| 5 | Adult chronic rhino-sinusitis: definitions, diagnosis, epidemiology, and pathophysiology 显示文摘 | Benninger MS Ferguson B J Hadtey JA | 2003 | Otolaryngol Head Neck Surg2003，129，： | 1 |
| 6 | Deletion of the mouse SlC30A8 gene encoding zinc transporter-8 results in impaired insulin secretion 显示文摘 | Pound LD Sarkar SA Benninger RK | 2009 | Biochem J2009，421，3： | 1 |
| 7 | Transcranial direct current stimulation for the treatment of Parkinson's disease显示文摘 | Benninger H D | 2010 | J Neurol Neurosurg Psychiatry2010，81，10： | 1 |
| 8 | Vocal fold scarring: Current concepts and management 显示文摘 | Benninger MS Alessi D Archer S | 1996 | Otolaryngol Head Neck Surg1996，115，： | 1 |
| 9 | Symptom-directed selective endoscopy:long-term efficacy显示文摘 | Benninger MS Shariff A Blazoff K | | 0，，07： | 1 |
| 10 | Bacterial interference in upper respiratory tract infections: A systematic review显示文摘 | Benninger M Brook I Bernstein JM | 2011 | American Journal of Rhinology & Allergy2011，25，2： | 1 |
| 11 | Cobla- tion of the canine vocal fold: a histologic study显示文摘 | DIVI V BENNINGER M KIUPEL M | 2012 | J Voice2012，26，： | 1 |
| 12 | Adult chronic rhinosinusitis: Definitions, diagnosis, epidemiology, and pathophysiology显示文摘 | Michael S. Benninger Berrylin J. Ferguson James A. Hadley Daniel L. Hamilos Michael Jacobs David W. Kennedy Donald C. Lanza Bradley F. Marple J.David Osguthorpe James A. Stankiewicz Jack Anon James Denneny Ivor Emanuel Howard Levine | 2003 | Otolaryngology - Head and Neck Surgery2003，，3： | 1 |
| 13 | The endoscopic management of sphenoid and ethmoid mucoceles with orbital and intranasal extension显示文摘 | Benninger M S Marks S | 1995 | Rhinology1995，33，3： | 1 |
| 14 | Increased preva-lence of hyperhomocysteinemia in cervical artery dissection causingstroke:a case-control study显示文摘 | Benninger DH Herrmann FR Georgiadis D | 2009 | Cerebrovasc Dis2009，27，： | 1 |
| 15 | Rhinosinusitis: Establishing definitions for clinical research and patient care显示文摘 | Eli O. Meltzer Daniel L. Hamilos James A. Hadley Donald C. Lanza Bradley F. Marple Richard A. Nicklas Claus Bachert James Baraniuk Fuad M. Baroody Michael S. Benninger Itzhak Brook Badrul A. Chowdhury Howard M. Druce Stephen Durham Berrylin Ferguson Jack | 2004 | The Journal of Allergy and Clinical Immunology2004，，6： | 1 |
| 16 | Seasonal variations in ^7Be activity in the sediments of Cape Lookout Bight, North Carolina 显示文摘 | Canuel E A Martens C S Benninger L K | 1990 | Geochim Cosmochim Acta1990，54，1： | 1 |
| 17 | Arabidopsis research 2001显示文摘 | Eckardt NA Araki T Benning C Cubas P Goodrich J Jacobsen SE Masson P Nambara E Simon R Somerville S Wasteneys G | | 0，，09： | 1 |
| 18 | Review Article A review of multi-channel indices of class separability显示文摘 | I. L. Thomas N. P. Ching V. M. Benning J. A. D’Aguanno | 1987 | International Journal of Remote Sensing1987，，3： | 1 |
| 19 | Accuracy of color duplex ultrasound diagnosis of spontaneous crotid dissection causing ischemia显示文摘 | Benninger DH Georgiadis D Gandjour J | 2006 | Stroke2006，37，2： | 1 |
| 20 | Mucociliary function following sinus mucosal regeneration显示文摘 | 3,Benninger MS Schmidt JL Crissman JD | 1991 | Otolaryngol Head Neck Surg1991，105，： | 1 |
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